Construction of a new model for screening antiarrhythmic drugs

Chinese Pharmacological Bulletin

Volumn 19, Issue 2, 2003, Pages 217-221

  Yang, Bao Feng ^a   Shan, Hong Li ^a   Zhou, Yu Hong ^a   Gong, Dong Mei ^a   Dong, De Li ^a   Du, Zhi Min ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Aconitine; Antiarrhythmia; Ionic channels; Model

Indexed keywords

ACONITINE; ANTIARRHYTHMIC AGENT; CALCIUM CHANNEL L TYPE; INWARDLY RECTIFYING POTASSIUM CHANNEL; QUINIDINE; VERAPAMIL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DISSOCIATION; DRUG EFFECT; EVALUATION; ION CURRENT; MUSCLE CELL; NONHUMAN; PATCH CLAMP; RAT; REPOLARIZATION; SODIUM CURRENT;

EID: 0037994294     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Nattel S, Singh BN. Evolution, mechanisms and classification of antiarrhythmic drugs: Focus on class III actions. Am J Cardiol, 1999;84(9A):11R-9R
2. Yang BF, Xu CQ, Li YR et al. Inhibitory effects of artemisine on cloned inward rectifier potassium channels. Chin J Pharmacol Toxicol, 1999;13:245-8
3. k and HERG channels of cardiac myocytes. Acta Pharmacol Sin, 2001;22(2):125-31
4. + currents in mammalian ventricular myocytes. Acta Pharmacol Sin. 1999:20(11):961-9
5. + channel, toxicity and antinociceptive properties. Eur J Pharmacol, 1997;337(2-3)3:165-74
6. Yeih DF, Chiang FT, Huang SK. Successful treatment of aconitine induced life threatening ventricular tachyarrhythmia with amiodarone, Heart, 2000;84(4):E8