A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein

Vox Sanguinis

Volumn 84, Issue 2, 2003, Pages 141-

  Kamesaki, T ^a   Kumada, M ^a   Omi, T ^a   Okuda, H ^a   Iwamoto, S ^a   Takahashi, J ^b   Kimura, K ^b   Hirayama, F ^b   Kamata, H ^c   Obara, K ^d   Taniguchi, M ^b   Tani, Y ^b   Kajii, E ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b SUWA RED CROSS HOSPITAL   (Japan)

^c Akita Red Cross Hospital   (Japan)

^d Iwate Blood Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GREEN FLUORESCENT PROTEIN; PROTEIN; PROTEIN RHD; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; EXON; GENE MUTATION; GENE SEQUENCE; HUMAN; JAPAN; LETTER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; SINGLE STRAND CONFORMATION POLYMORPHISM; SITE DIRECTED MUTAGENESIS;

HLA-D ANTIGENS; HUMANS; JAPAN; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RH-HR BLOOD-GROUP SYSTEM;

EID: 0037989810     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.2003.00274.x     Document Type: Letter

References (4)

1. Wagner FF, Gassner C, Muller TH, Schonitzer D, Schunter F, Flegel WA: Molecular basis of weak D phenotypes. Blood 1999; 93:385-393
2. Wagner FF, Frohmajer A, Ladewig B, Eicher NI, Lonicer CB, Muller TH, Siegel MH, Flegel WA: Weak D alleles express distinct phenotypes. Blood 2000; 95:2699-2708
3. Kamesaki T, Iwamoto S, Kumada M, Omi T, Okuda H, Tanaka M, Takahashi J, Obara K, Seno T, Tani Y, Kajii E: Molecular characterization of weak D phenotypes by site-directed mutagenesis and expression of mutant Rh-green fluorescence protein fusions in K562 cells. Vox Sang 2001; 81:254-258
4. Wagner FF, Flegel WA: The RhesusBase. Ulm, DRK-Blutspendedienst Baden-Wuerttemberg 2001. Available at http://www.uniulm.de/~fwagner/RH/RB