Effect of correction of anemia with erythropoietin and intravenous iron in resistant heart failure in octogenarians

Israel Medical Association Journal

Volumn 5, Issue 5, 2003, Pages 337-339

  Silverberg, Donald S ^a   Wexler, Dov ^a   Blum, Miriam ^a   Schwartz, Doron ^a   Keren, Gad ^a   Sheps, David ^a   Iaina, Adrian ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Anemia; Elderly; Erythropoietin; Heart failure; Iron; Octogenarians; Renal failure

Indexed keywords

DRUG THERAPY; ENZYME INHIBITION; HEMOGLOBIN; PATIENT MONITORING; SUGAR (SUCROSE);

HEART FAILURE;

PATIENT TREATMENT;

CREATININE; ERYTHROPOIETIN; FERRIC HYDROXIDE SUCROSE; FERRITIN; FUROSEMIDE; HEMOGLOBIN; IRON;

ADULT; AGED; ANEMIA; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE RESISTANCE; DISEASE SEVERITY; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFECT; DYSPNEA; ELDERLY CARE; FATIGUE; FEMALE; GERIATRIC PATIENT; HEART FAILURE; HEART FUNCTION; HEMOGLOBIN DETERMINATION; HOSPITALIZATION; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; QUALITY OF LIFE;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANEMIA; DRUG THERAPY, COMBINATION; ERYTHROPOIETIN; FEMALE; FERRIC COMPOUNDS; GLOMERULAR FILTRATION RATE; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; HUMANS; INFUSIONS, INTRAVENOUS; KIDNEY FAILURE; MALE; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0037983911     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Miller LW, Missov ED. Epidemiology of heart failure. Cardiol Clin 2001;19:547-55.
2. Rich MW. Heart failure in the 21st century: A cardiogeriatric syndrome. J Gerontol 2001;56A:M88-96.
3. Krumholz, Parent EM, Tu N, et al. Readmission after hospitalizations for congestive heart failure among medicare beneficiaries. Arch Intern Med 1997;157:99-104.
4. Croft JB, Giles WH, Pollard RA, et al. Heart failure survival among older adults in the United States. Arch Intern Med 1999;159:505-10.
5. Mac Intyre K, Capewell S, Stewart S, et al. Evidence of improving prognosis in heart failure. Circulation 2000;102:1126-31.
6. Feldman DE, Thivirerge C, Guerard L, et al. Changing trends for mortality and admissions to hospital for elderly with congestive heart failure in Montreal. Can Med Assoc J 2001;165:1033-6.
7. Ceia F, Fonseca C, Mota T, et al. Prevalence of chronic heart failure in Southwestern Europe: The EPICA Study. Eur J Heart Fail 2002;4:531-9.
8. Silverberg DS, Wexler D, Blum M, et al. The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function, functional cardiac class, and markedly reduces hospitalizations. J Am Coll Cardiol 2000;35:1737-44.
9. Kratz A, Lewandrowski KB. Normal reference laboratory values. N Engl J Med 1998;339:1063-72.
10. Silverberg DS, Iaina A, Wexler D, et al The pathological consequences of anaemia. Clin Lab Haematol 2001;23:1-6.
11. Tong EM, Nissenson AR. Erythropoietin and anemia. Semin Nephrol 2001;21:190-203.
12. Sunder-Plassmann G, Horl WH. Effect of erythropoietin on cardiovascular diseases. Am J Kidney Dis 2001;38(Suppl 1):S20-5.
13. Silverberg DS, Wexler D, Sheps D, et al. The effect of correction of mild anemia in severe resistant heart failure using subcutaneous erythropoietin and intravenous iron: A randomized controlled study. J Am Coll Cardiol 2001;37:1775-80.
14. Silverberg DS, Wexler D, Blum M, et al. The effect of correction of anemia in diabetic and non diabetic with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron. Nephrol Dial Transplant 2003;19:141-6.
15. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
16. St. Peter WL, Xue J, Ebben J, Collins A. Pre-end stage renal disease erythropoietin use predicts hospitalization in the periods before and after end-stage renal disease diagnosis. J Am Soc Nephrol 2001;12:Abstr. 1274.
17. Khand AU, Gemmell I, Rankin AC, Cleland JGF. Clinical events leading to the progression of heart failure: Insights from a national database of hospital discharges. Eur Heart J 2001;22:153-64.
18. Al-Ahmad A, Levey A, Rand W, et al. Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction. J Am Coll Cardiol 2001;38:955-62.
19. Horwich TB, Fonarow GC, Hamilton MA, et al. Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J Am Coll Cardiol 2002;39:1780-6.
20. McClellan WM, Flanders WD, Langston RD, et al. Anemia and renal insufficiency are independent risk factors for death among patients with congestive heart failure admitted to community hospitals: A population-based study. J Am Soc Nephrol 2002;13:1928-36.
21. Alexander M, Grumbach K, Remy L. et al. Congestive heart failure hospitalizations and survival in California: Patterns according to race/ethnicity. Am Heart J 1999;137:919-27.
22. Polanczyk CA, Newton C, Dec GC, et al. Quality of care and hospital readmission in congestive heart failure: An explicit review process. J Card Fail 2001;7:289-98.
23. Wu W-C, Rathore SS, Wang Y, et al. Blood transfusion in elderly patients with acute myocardial infarction. N Engl J Med 2001;345:1230-6.