Effect of catechol derivatives on cell growth and lipoxygenase activity

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 15, 2003, Pages 2435-2439

  Simpson, Julie ^a   Forrester, Rebecca ^a   Tisdale, Michael J ^a   Billington, David C ^a,b   Rathbone, Daniel L ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b L'Oréal Advanced Research   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,5 TRIMETHYL 6 (3 PYRIDYLMETHYL) 1,4 BENZOQUINONE; ANTINEOPLASTIC AGENT; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; BAICALEIN; CATECHOL DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FISETIN; LIPOXYGENASE INHIBITOR; LUTEOLIN; PHENOL DERIVATIVE; SALICYLIC ACID DERIVATIVE;

ANIMAL; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL DIVISION; COLON TUMOR; CONFORMATION; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; IC 50; IN VITRO STUDY; METABOLISM; MOUSE; NONHUMAN; RABBIT; RETICULOCYTE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL; TUMOR CELL LINE;

MURINAE; ORYCTOLAGUS CUNICULUS;

EID: 0037972031     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00528-6     Document Type: Article

References (19)

1. Rioux N., Castonguay A. Carcinogenesis. 19:1998;1393.
2. Bandyopadhyay G.K., Imagawa N., Wallace D.R., Nandi S. J. Biol. Chem. 263:1988;7567.
3. Honn K.V., Tang D.G., Gao X., Butovich I.A., Liu B., Timar J., Hagmann W. Cancer Metastasis Rev. 13:1994;365.
4. Liu B., Maler R.J., Hannun Y.A., Porter A.T., Honn K.V. J. Natl. Cancer Inst. 86:1994;1145.
5. Honn K.V., Tang D.G., Duniec Z.M., Grossi I.M., Timar J., Renaud C., Leithauser M., Blair I., Diglio C.A., Kimler V.A., Taylor J.D., Marnett L.J. Cancer Res. 54:1994;565.
6. Lysz T.W., Arora J.K., Lin C., Zelenka P.S. Cell Growth Differ. 5:1994;1069.
7. Tang D.G., Gunn K.-L., Li L., Honn K.V., Chen Y.Q., Rice R.L., Taylor J.D., Porter A.T. Int. J. Cancer. 72:1997;1078.
8. Ding X.-Z., Kuszynski C.A., El-Metivally T.H., Adrian T.E. Biochem. Biophys. Res. Commun. 266:1999;392.
9. Hussey H.J., Tisdale M.J. Br. J. Cancer. 74:1996;683.
10. Hussey H.J., Bibby M.C., Tisdale M.J. Br. J. Cancer. 73:1996;1187.
11. Hussey H.J., Tisdale M.J. Br. J. Cancer. 75:1997;845.
12. Hussey H.J., Tisdale M.J. Br. J. Cancer. 74:1996;1349.
13. Cho H., Ueda M., Tamaoka M., Hamaguchi M., Aisaka K., Kiso Y., Inoue T., Ogino R., Tatsuoka T., Ishihara T. J. Med. Chem. 34:1991;1503.
14. Tait B.D., Dyer R.D., Auerbach B.J., Bornemeier D., Guilds-Zamarka L., Oxender M., Roth B.D., Trevedi B.K., Cornicelli J.A. Bioorg. Med. Chem. Lett. 6:1996;93.
15. Pegorier L., Petit Y., Larcheveque M. Chem. Commun. 1994;633.
16. 4 cells per well (MAC16) in 1 mL of growth medium and left for 24 h before drug addition. All drugs were dissolved in DMSO and diluted in culture medium such that the final concentration of DMSO did not exceed 1%. Control wells contained solvent alone. Cell numbers were determined 72 h after drug addition using a Coulter Counter model ZM.
17. 50 determination (n=2) on rabbit reticulocyte 15-lipoxygenase.
18. Sadik D.D., Sies H., Schewe T. Biochmem Pharmacol. 2003;773.
19. 11. Radioactivity and UV absorbance at 237 nm were monitored. Peaks were identified based on the retention times of authentic standards.