Effects of epistasis on phenotypic robustness in metabolic pathways

Mathematical Biosciences

Volumn 184, Issue 1, 2003, Pages 27-51

  Bagheri Chaichian, Homayoun ^a,b   Hermisson, Joachim ^b   Vaisnys, Juozas R ^b,c   Wagner, Günter P ^b  

^a SANTA FE INSTITUTE   (United States)

^b YALE UNIVERSITY   (United States)

^c Yale University   (United States)

Author keywords

Dominance; Epistasis; Metabolic control analysis; Robustness; Summation theorem

Indexed keywords

COMPUTER SIMULATION; ENZYME KINETICS; GENETIC ENGINEERING; MATHEMATICAL MODELS;

EVOLUTIONARY MODIFICATIONS;

PHYSIOLOGY;

ENZYME;

EPISTASIS; GENE EXPRESSION; METABOLISM; PHENOTYPE;

EPISTASIS; GENOTYPE PHENOTYPE CORRELATION; MATHEMATICAL MODEL; METABOLIC REGULATION; MOLECULAR EVOLUTION; REVIEW;

EID: 0037971416     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0025-5564(03)00057-9     Document Type: Review

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