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Volumn 29, Issue 3, 2003, Pages 123-131

A new therapeutic approach: Topotecan plus gemcitabine in the treatment of patients with relapsed ovarian cancer after failure of first-line chemotherapy with paclitaxel and platinum

Author keywords

Chemotherapy; Gemcitabine; Ovarian cancer; Topotecan

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CARBOPLATIN; GEMCITABINE; PACLITAXEL; PLATINUM; SEROTONIN 3 ANTAGONIST; TOPOTECAN; VISCUM ALBUM LECTIN; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; PLATINUM DERIVATIVE;

EID: 0037968836     PISSN: 13418076     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1341-8076.2003.00087.x     Document Type: Article
Times cited : (9)

References (44)
  • 1
    • 0003319761 scopus 로고    scopus 로고
    • GLOBOCAN 2000. Cancer incidence, mortality and prevalence worldwide, Version 1.0
    • Lyon: IARCPress
    • Ferlay JF, Pisani P, Parkin DM. GLOBOCAN 2000. Cancer incidence, mortality and prevalence worldwide, Version 1.0. IARC Cancerbase No. 5. Lyon: IARCPress, 2001.
    • (2001) IARC Cancerbase , Issue.5
    • Ferlay, J.F.1    Pisani, P.2    Parkin, D.M.3
  • 2
    • 0032933511 scopus 로고    scopus 로고
    • Advanced epithelial ovarian cancer: 1998 consensus statements
    • Berek JS, Bertelsen K, Du Bois A et al. Advanced epithelial ovarian cancer: 1998 consensus statements. Ann Oncol 1999; 10 (Suppl.): 87-92.
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL. , pp. 87-92
    • Berek, J.S.1    Bertelsen, K.2    Du Bois, A.3
  • 3
    • 0032439994 scopus 로고    scopus 로고
    • Operative results after primary and secondary debulking-operations in advanced ovarian cancer
    • Lichtenegger W, Sehouli J, Buchmann E. Operative results after primary and secondary debulking-operations in advanced ovarian cancer. J Obstet Gyn Res 1998; 24: 447-451.
    • (1998) J Obstet Gyn Res , vol.24 , pp. 447-451
    • Lichtenegger, W.1    Sehouli, J.2    Buchmann, E.3
  • 4
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and IV ovarian cancer
    • McGuire PW, Hoskins WJ, Brady MF. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and IV ovarian cancer. N Engl J Med 1996; 334: 1-6.
    • (1996) N Engl J Med , vol.334 , pp. 1-6
    • McGuire, P.W.1    Hoskins, W.J.2    Brady, M.F.3
  • 5
    • 0000012867 scopus 로고    scopus 로고
    • Cisplatin/paclitaxel vs carboplatin/paclitaxel in ovarian cancer: Update of an Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group trial
    • abstract 1374
    • Du Bois A, Lueck HJ, Meier W. Cisplatin/paclitaxel vs carboplatin/paclitaxel in ovarian cancer: Update of an Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group trial. Proceedings of the American Society of Clinical Oncology 1999; 19, abstract 1374.
    • (1999) Proceedings of the American Society of Clinical Oncology , vol.19
    • Du Bois, A.1    Lueck, H.J.2    Meier, W.3
  • 6
    • 0031745255 scopus 로고    scopus 로고
    • Chemotherapy of advanced ovarian cancer
    • McGuire PW & Ozols RF. Chemotherapy of advanced ovarian cancer. Seminars Oncol 1998; 25: 340-348.
    • (1998) Seminars Oncol , vol.25 , pp. 340-348
    • McGuire, P.W.1    Ozols, R.F.2
  • 7
    • 0000121237 scopus 로고    scopus 로고
    • Randomized phase III study of cisplatin (CIS)/paclitaxel (PAC) vs carboplatin (CARBO)/paclitaxel (PAC) in optimal Stage III epithelial ovarian cancer (GOG 158)
    • abstract 1373
    • Ozols RF, Bundy BN, Fowler J. Randomized phase III study of cisplatin (CIS)/paclitaxel (PAC) vs carboplatin (CARBO)/paclitaxel (PAC) in optimal Stage III epithelial ovarian cancer (GOG 158). Proceedings of the American Society of Clinical Oncology 1999; 18, abstract 1373.
    • (1999) Proceedings of the American Society of Clinical Oncology , vol.18
    • Ozols, R.F.1    Bundy, B.N.2    Fowler, J.3
  • 10
    • 0034884941 scopus 로고    scopus 로고
    • Second-line treatment and consolidation therapies in advanced ovarian cancer
    • Conte PF, Gadducci A, Cianci C. Second-line treatment and consolidation therapies in advanced ovarian cancer. Int J Gynecol Cancer 2001; 11 (S1): 52-56.
    • (2001) Int J Gynecol Cancer , vol.11 , Issue.S1 , pp. 52-56
    • Conte, P.F.1    Gadducci, A.2    Cianci, C.3
  • 11
    • 0001076840 scopus 로고    scopus 로고
    • Lack of improvement in survival in patients with relapsed or refractory epithelial ovarian cancer, 1980-1997
    • abstract 1385
    • Knopf K, Brown M, Kohn EC. Lack of improvement in survival in patients with relapsed or refractory epithelial ovarian cancer, 1980-1997. ASCO Proceedings 1998; 17: abstract 1385, 359.
    • (1998) ASCO Proceedings , vol.17 , pp. 359
    • Knopf, K.1    Brown, M.2    Kohn, E.C.3
  • 12
    • 0026086870 scopus 로고
    • Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin
    • Markman M, Rothman R, Hakes T et al. Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin. J Clin Oncol 1991; 9: 389-393.
    • (1991) J Clin Oncol , vol.9 , pp. 389-393
    • Markman, M.1    Rothman, R.2    Hakes, T.3
  • 13
    • 0011930044 scopus 로고    scopus 로고
    • Development of a Symptom-Check-List for patients with advanced ovarian cancer. Results from a phase I and II clinical trial
    • abstract 2531
    • Walle U, Sehouli J, Stengel D et al. on behalf of the NOGGO Study Group, Charite. Virchow University Hospital, Berlin, Germany. Development of a Symptom-Check-List for patients with advanced ovarian cancer. Results from a phase I and II clinical trial. Proceedings of ASCO 2001 20: abstract 2531.
    • (2001) Proceedings of ASCO , vol.20
    • Walle, U.1    Sehouli, J.2    Stengel, D.3
  • 14
    • 0031786482 scopus 로고    scopus 로고
    • Topotecan for the treatment of advanced epithelial ovarian cancer: An open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel
    • Bookman MA, Malmstrom H, Bolis G et al. Topotecan for the treatment of advanced epithelial ovarian cancer: An open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel. J Clin Oncol 1998; 16: 3345-3352.
    • (1998) J Clin Oncol , vol.16 , pp. 3345-3352
    • Bookman, M.A.1    Malmstrom, H.2    Bolis, G.3
  • 15
    • 0034886499 scopus 로고    scopus 로고
    • Developmental chemotherapy in advanced ovarian cancer: Incorporation of topoisomerase-I inhibitors and perspective of the Gynecologic Oncology Group
    • Bookman MA. Developmental chemotherapy in advanced ovarian cancer: Incorporation of topoisomerase-I inhibitors and perspective of the Gynecologic Oncology Group. Int J Gynecol Cancer 2001; 11: (S1): 42-51.
    • (2001) Int J Gynecol Cancer , vol.11 , Issue.S1 , pp. 42-51
    • Bookman, M.A.1
  • 17
    • 10544229791 scopus 로고    scopus 로고
    • Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: Results of a large European phase II study
    • Creemers GJ, Bolis G, Gore M et al. Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: Results of a large European phase II study. J Clin Oncol 1996; 14: 3056-3061.
    • (1996) J Clin Oncol , vol.14 , pp. 3056-3061
    • Creemers, G.J.1    Bolis, G.2    Gore, M.3
  • 18
    • 9244247616 scopus 로고    scopus 로고
    • Phase II study of intravenous topotecan as a 5-day infusion for refractory epithelial ovarian carcinoma
    • Kudelka AP, Tresukosol D, Edwards CL et al. Phase II study of intravenous topotecan as a 5-day infusion for refractory epithelial ovarian carcinoma. J Clin Oncol 1996; 14: 1552-1557.
    • (1996) J Clin Oncol , vol.14 , pp. 1552-1557
    • Kudelka, A.P.1    Tresukosol, D.2    Edwards, C.L.3
  • 19
    • 0030900145 scopus 로고    scopus 로고
    • Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer
    • Ten Bokkel Huinink W, Gore M, Carmichael J et al. Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer. J Clin Oncol 1997; 15: 2183-2193.
    • (1997) J Clin Oncol , vol.15 , pp. 2183-2193
    • Ten Bokkel Huinink, W.1    Gore, M.2    Carmichael, J.3
  • 20
    • 0035300609 scopus 로고    scopus 로고
    • Clinical evidence for topotecan-paclitaxel non-cross-resistance in ovarian cancer
    • Gore M, Ten Bokkel Huinink W, Carmichael J et al. Clinical evidence for topotecan-paclitaxel non-cross-resistance in ovarian cancer. J Clin Oncol 2001; 19: 1893-1900.
    • (2001) J Clin Oncol , vol.19 , pp. 1893-1900
    • Gore, M.1    Ten Bokkel Huinink, W.2    Carmichael, J.3
  • 21
    • 0028024504 scopus 로고
    • Preclinical and phase I trials of topoisomerase I inhibitors
    • Von Hoff DD, Burris HA, Eckardt J. Preclinical and phase I trials of topoisomerase I inhibitors. Cancer Chemother Pharmacol 1994; 34 (Suppl.): 41-45.
    • (1994) Cancer Chemother Pharmacol , vol.34 , Issue.SUPPL. , pp. 41-45
    • Von Hoff, D.D.1    Burris, H.A.2    Eckardt, J.3
  • 22
    • 4243212488 scopus 로고    scopus 로고
    • Sequential topotecan and etoposid in pretreated ovarian cancer: A GINECO phase II study
    • abstract 1371
    • Ganem G, Gladieff L, Guastalla JP. Sequential topotecan and etoposid in pretreated ovarian cancer: A GINECO phase II study. Proceedings of ASCO 1998; 18: abstract 1371.
    • (1998) Proceedings of ASCO , vol.18
    • Ganem, G.1    Gladieff, L.2    Guastalla, J.P.3
  • 23
    • 0011960370 scopus 로고    scopus 로고
    • A phase I study of sequential topotecan and infusional etoposide phosphate in recurrent ovarian cancer
    • abstract 871
    • Madhusudan S & Deplanque G, Levitt NA. A phase I study of sequential topotecan and infusional etoposide phosphate in recurrent ovarian cancer. Proceedings of ASCO 2001; 21: abstract 871.
    • (2001) Proceedings of ASCO , vol.21
    • Madhusudan, S.1    Deplanque, G.2    Levitt, N.A.3
  • 24
    • 10544249871 scopus 로고    scopus 로고
    • Sequences of topotecan and cisplatin: Phase I, pharmacologic and in vitro studies to examine sequence dependence
    • Rowinsky EK, Kaufmann SH, Baker SD et al. Sequences of topotecan and cisplatin: Phase I, pharmacologic and in vitro studies to examine sequence dependence. J Clin Oncol 1996; 14: 3074-3084.
    • (1996) J Clin Oncol , vol.14 , pp. 3074-3084
    • Rowinsky, E.K.1    Kaufmann, S.H.2    Baker, S.D.3
  • 25
    • 0011982368 scopus 로고    scopus 로고
    • Phase I trial of topotecan in combination with gemcitabine in platinum and paclitaxel refractory ovarian cancer
    • abstract 1482
    • Sehouli J, Lichtenegger W, Schnborn J. Phase I trial of topotecan in combination with gemcitabine in platinum and paclitaxel refractory ovarian cancer. Proceedings of ASCO 1999; 18: abstract 1482.
    • (1999) Proceedings of ASCO , vol.18
    • Sehouli, J.1    Lichtenegger, W.2    Schnborn, J.3
  • 26
    • 1542667103 scopus 로고    scopus 로고
    • Topotecan (T) and cyclophosphamide (Cy) in second line treatment of advanced ovarian cancer (AOC): A GINECO phase II trial
    • abstract 811
    • Vannetzel JM, Fabbro M, Weber B. Topotecan (T) and cyclophosphamide (Cy) in second line treatment of advanced ovarian cancer (AOC): A GINECO phase II trial. Proceedings of ASCO 2001; 20: abstract 811.
    • (2001) Proceedings of ASCO , vol.20
    • Vannetzel, J.M.1    Fabbro, M.2    Weber, B.3
  • 27
    • 0025325071 scopus 로고
    • Evaluation of the antitumor activity of gemcitabine
    • Hertel L, Boder GB, Kroin JS. Evaluation of the antitumor activity of gemcitabine. Cancer Res 1990; 50: 4417-4422.
    • (1990) Cancer Res , vol.50 , pp. 4417-4422
    • Hertel, L.1    Boder, G.B.2    Kroin, J.S.3
  • 28
    • 0038562886 scopus 로고    scopus 로고
    • Phase II study: Gemcitabine in refractory metastatic prostatic carcinoma
    • abstract 1109
    • Morant R. Phase II study: Gemcitabine in refractory metastatic prostatic carcinoma. Proceedings of ASCO 1997; 16: abstract 1109.
    • (1997) Proceedings of ASCO , vol.16
    • Morant, R.1
  • 29
    • 0000128382 scopus 로고    scopus 로고
    • Gemcitabine, carboplatin, and paclitaxel (GCP) as first-line treatment of ovarian cancer FIGO stages IIB-IV
    • abstract 1395
    • Hansen SW, Anderson H, Boman K, Hansen MI. Gemcitabine, carboplatin, and paclitaxel (GCP) as first-line treatment of ovarian cancer FIGO stages IIB-IV. Proceedings of the Ann Meet Am Soc Clin Oncol 1999; 18: abstract 1395.
    • (1999) Proceedings of the Ann Meet Am Soc Clin Oncol , vol.18
    • Hansen, S.W.1    Anderson, H.2    Boman, K.3    Hansen, M.I.4
  • 30
    • 0028020890 scopus 로고
    • Phase II study of gemcitabine (2′2′-difluorodeooxycytidine) in previously treated ovarian cancer patients
    • Lund B, Hensen OP, Theilade K. Phase II study of gemcitabine (2′2′-difluorodeooxycytidine) in previously treated ovarian cancer patients. J Natl Cancer Inst 1994; 86: 1530-1533.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1530-1533
    • Lund, B.1    Hensen, O.P.2    Theilade, K.3
  • 31
    • 0030272511 scopus 로고    scopus 로고
    • Activity of gemcitabine in patients with advanced ovarian cancer. Responses seen following platinum and paclitaxel
    • Shapiro JD, Millward MJ, Rischin D. Activity of gemcitabine in patients with advanced ovarian cancer. Responses seen following platinum and paclitaxel. Gynecol Oncol 1996; 63: 89-93.
    • (1996) Gynecol Oncol , vol.63 , pp. 89-93
    • Shapiro, J.D.1    Millward, M.J.2    Rischin, D.3
  • 34
    • 0028060511 scopus 로고
    • Practical modifications of the continual reassessment method for phase 1 cancer clinical trials
    • Faries D. Practical modifications of the continual reassessment method for phase 1 cancer clinical trials. J Biopharm 1994; 4: 147-164.
    • (1994) J Biopharm , vol.4 , pp. 147-164
    • Faries, D.1
  • 35
    • 7044220940 scopus 로고
    • Common toxicity criteria
    • In: Perry MC, eds.; Baltimore: Williams & Wilkins
    • National Cancer Institute. Common toxicity criteria. In: Perry MC, eds. The Chemotherapy Source Book. Baltimore: Williams & Wilkins, 1990, 1133-1140.
    • (1990) The Chemotherapy Source Book , pp. 1133-1140
  • 36
    • 0034575304 scopus 로고    scopus 로고
    • Antagonistic effect of the combination of gemcitabine/topotecan in ovarian cancer cells
    • Distefano M, Ferlini C, De-Vincenzo R, Gaggini C, Manusco S, Scambia G. Antagonistic effect of the combination of gemcitabine/topotecan in ovarian cancer cells. Oncol Res 2001; 12: 355-359.
    • (2001) Oncol Res , vol.12 , pp. 355-359
    • Distefano, M.1    Ferlini, C.2    De-Vincenzo, R.3    Gaggini, C.4    Manusco, S.5    Scambia, G.6
  • 37
    • 0031456165 scopus 로고    scopus 로고
    • Life-threatening myelosuppression in patients with occult renal impairment receiving topotecan
    • O'Reilly S, Armstrong DK, Grochow LB. Life-threatening myelosuppression in patients with occult renal impairment receiving topotecan. Gynecol Oncol 1997; 67: 329-330.
    • (1997) Gynecol Oncol , vol.67 , pp. 329-330
    • O'Reilly, S.1    Armstrong, D.K.2    Grochow, L.B.3
  • 38
    • 0038224173 scopus 로고    scopus 로고
    • Phase I trial of topotecan and gemcitabine for patients with previously treated, advanced non-small cell cancer
    • abstract 1930
    • Cole JL, Rinaldi DA, Lormand NA. Phase I trial of topotecan and gemcitabine for patients with previously treated, advanced non-small cell cancer. Proceedings of ASCO 1999; 18: abstract 1930.
    • (1999) Proceedings of ASCO , vol.18
    • Cole, J.L.1    Rinaldi, D.A.2    Lormand, N.A.3
  • 39
    • 0003256828 scopus 로고    scopus 로고
    • Combined therapy with topotecan and gemcitabine in patients with inoperable or metastatic NSCLC
    • abstract 1930
    • Dabrow MB, Gilman PB, Meyer TJ. Combined therapy with topotecan and gemcitabine in patients with inoperable or metastatic NSCLC. Proceedings of ASCO 1999; 18: abstract 1930.
    • (1999) Proceedings of ASCO , vol.18
    • Dabrow, M.B.1    Gilman, P.B.2    Meyer, T.J.3
  • 41
    • 0035878628 scopus 로고    scopus 로고
    • A phase I trial of topotecan and gemcitabine administered weekly for 3 consecutive weeks to patients with advanced tumors
    • Sun W, Stevenson JP, Gallagher M et al. A phase I trial of topotecan and gemcitabine administered weekly for 3 consecutive weeks to patients with advanced tumors. Cancer 2001; 92: 414-419.
    • (2001) Cancer , vol.92 , pp. 414-419
    • Sun, W.1    Stevenson, J.P.2    Gallagher, M.3
  • 42
    • 0035165048 scopus 로고    scopus 로고
    • Topotecan and gemcitabine in platinum/paclitaxel-resistant ovarian cancer
    • Greggi S, Salerno MG, D'Agostino G et al. Topotecan and gemcitabine in platinum/paclitaxel-resistant ovarian cancer. Oncology 2001; 60: 19-23.
    • (2001) Oncology , vol.60 , pp. 19-23
    • Greggi, S.1    Salerno, M.G.2    D'Agostino, G.3
  • 43
    • 0033816778 scopus 로고    scopus 로고
    • A dose escalating study of topotecan preceding cisplatin in previously untreated patients with small-cell lung cancer
    • Sorensen M, Jensen PB, Herrstedt H et al. A dose escalating study of topotecan preceding cisplatin in previously untreated patients with small-cell lung cancer. Ann Oncol 2000; 11: 829-835.
    • (2000) Ann Oncol , vol.11 , pp. 829-835
    • Sorensen, M.1    Jensen, P.B.2    Herrstedt, H.3
  • 44
    • 0036862310 scopus 로고    scopus 로고
    • A phase II study of topotecan plus gemcitabine in the treatment of patients with relapsed ovarian cancer after failure of first-line chemotherapy
    • Sehouli J, Stengel D, Oskay G et al. A phase II study of topotecan plus gemcitabine in the treatment of patients with relapsed ovarian cancer after failure of first-line chemotherapy. Ann Oncol 2002; 13: 1749-1755.
    • (2002) Ann Oncol , vol.13 , pp. 1749-1755
    • Sehouli, J.1    Stengel, D.2    Oskay, G.3


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