Spontaneous dyskinesia in first-degree relatives of chronically ill, never-treated people with schizophrenia

British Journal of Psychiatry

Volumn 183, Issue JULY, 2003, Pages 45-49

  McCreadie, Robin G ^a   Thara, Rangaswamy ^b   Srinivasan, Tirupati N ^b   Padmavathi, Ramachandra ^b  

^a Crichton Royal Hospital   (United Kingdom)

^b SCHIZOPHRENIA RESEARCH FOUNDATION   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; DYSKINESIA; FEMALE; HUMAN; INDIA; INVOLUNTARY MOVEMENT; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; PARKINSONISM; PREVALENCE; RELATIVE; SCHIZOPHRENIA; SIBLING;

ADULT; AGED; CHRONIC DISEASE; DYSKINESIAS; FEMALE; HUMANS; INDIA; MALE; MIDDLE AGED; PARKINSONIAN DISORDERS; PREVALENCE; SCHIZOPHRENIA; SIBLINGS;

EID: 0037963734     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.183.1.45     Document Type: Article

References (18)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). Washington, DC: APA.
2. Cantor-Graae, E., Ismail, B. & McNeil, T. F. (2000) Are neurological abnormalities in schizophrenic patients and their siblings the result of perinatal trauma. Acta Psychiatrica Scandinavica, 101, 142-147.
3. Egan, M. E., Hyde, T. M., Bonomo, J. B., et al (2001) Relative risk of neurological signs in siblings of patients with schizophrenia. American Journal of Psychiatry, 158, 1827-1834.
4. Ismail, B., Cantor-Graae, E. & McNeil, T. F. (1990) Neurological abnormalities in schizophrenic patients and their siblings. American Journal of Psychiatry, 155, 84-89.
5. _ & _ (2001) Neurodevelopmental origins of tardivelike dyskinesia in schizophrenia patients and their siblings. Schizophrenia Bulletin, 27, 629-641.
6. Kay, S. R., Fiszbein, A. & Opler, L. A. (1907) The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276.
7. Kinney, D. K., Woods, B. T. & Yurgelun-Todd, M. A. (1906) Neurological abnormalities in schizophrenic patients and their families. Archives of General Psychiatry, 43, 665-668.
8. Lerer, R., Segman, R. H., Fangerau, H., et al (2002) Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene ser9gly polymorphism Neuropsychopharmacology, 27, 105- 119.
9. Lovlie, R., Thara, R., Padmavathi, R., et al (2001) Ser9Gly dopamine D3 receptor polymorphism and spontaneous dyskinesia in never-medicated schizophrenic patients. Molecular Psychiatry, 6, 6-7.
10. McCreadie, R. G., Thara, R., Kamath, S., et al (1996) Abnormal movements in never-medicated Indian patients with schizophrenia. British Journal of Psychiatry, 168, 221-226.
11. _, Latha, S., Thara, R., et al (1997) Poor memory, negative symptoms and abnormal movements in never-treated Indian patients with schizophrenia. British Journal of Psychiatry, 171, 360-363.
12. _, Thara, R., Padmavathi, R., et al (2002a) Structural brain differences between never treated people with schizophrenia, with and without dyskinesia, and normal control subjects. A magnetic resonance imaging study. Archives of General Psychiatry, 59, 332-336.
13. _, Padmavathi, R., Thara, R., et al (2002b) Spontaneous dyskinesia and parkinsonism in never-medicated chronically ill patients with schizophrenia: 18-month follow-up. British Journal of Psychiatry, 181, 135-137.
14. Nilsson, A., Waller, L., Rosengreen, A., et al (1997) Cigarette smoking is associated with abnormal involuntary movements in the general male population - a study of men born in 1933. Biological Psychiatry, 41, 717-723.
15. Schooler, N. R. & Kane, J. M. (1902) Research diagnoses for tardive dyskinesia. Archives of General Psychiatry, 39, 486-487.
16. Silverman, J. M., Siever, L. J., Horvath, T. B., et al (1993) Schizophrenia-related and affective personality disorder traits in relatives of probands with schizophrenia and personality disorders. American Journal of Psychiatry, 150, 435-442
17. Simpson, G. M. & Angus, J. W. S. (1970) A rating scale for extrapyramidal side effects. Acta Psychiatrica Scandinavica Supplementum, 212, 11-19.
18. US Department of Health, Education and Welfare (1976) Abnormal Involuntary Movements Scale (AIMS). In ECDEU Assessment Manual for Pharmacology (ed. W Guy). Rockville, MD: US Department of Health, Education and Welfare.