Effect of extraction of myosin binding protein C on contractility of rat heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 2 54-2, 2003, Pages

  Kulikovskaya, I ^a   McClellan, G ^a   Levine, R ^b   Winegrad, S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiomyopathy; Filament stability; Thick filament structure

Indexed keywords

CALCIUM; MYOSIN BINDING PROTEIN C;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART DILATATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

EID: 0037962159     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00841.2002     Document Type: Article

References (24)

1. 2+ in intact rat ventricular myocytes. J Physiol 528: 151-156, 2000.
2. Carrier L, Bonne G, Bahrend E, Yu B, Richard P, Niel F, Hainque B, Cruard C, Gary F, Labiet S, Bouhour JB, Dubourg O, Desnos M, Hagege AA, Trent RJ, Komajda M, Fiszman M, and Schwartz K. Organization and sequence of human cardiac myosin binding protein C gene (MyBP-C3) and identification of the mutations predicted to produce truncated proteins in familial hypertrophic cardiomyopathy. Circ Res 80: 427-434, 1997.
3. Flavigny J, Souchet M, Sebillon P, Berrebi-Bertrand I, Hainque B, Mallet A, Bril A, Schwartz K, and Carrier L. COOH-terminal truncated cardiac myosin binding protein C mutants resulting from familial hypertrophic cardiomyopathy mutations exhibit altered expression and/or incorporation into fetal rat cardiomyocytes. J Mol Biol 294: 443-456, 1999.
4. Gautel M, Zuffardi O, Freiberg A, and Labeit S. Phosphorylation switches specific for the cardiac isoform of myosin binding protein C: moderator of cardiac contraction? EMBO J 14: 1952-1960, 1995.
5. Gruen M and Gautel M. Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin binding protein C. J Mol Biol 286: 933-949, 1999.
6. Harris SP, Bartley CR, Hacker TA, McDonald KS, Douglas PS, Greaser ML, Powers PA, and Moss RL. Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. Circ Res 90: 594-601, 2002.
7. Hartzell HC and Glass DB. Phosphorylation of purified cardiac muscle C-protein by purified cAMP-dependent and endogenous calmodukin-dependent protein kinase. J Biol Chem 259: 15587-15596, 1984.
8. Hofmann PA, Hartzell HC, and Moss RL. Alterations in Ca sensitive tension due to partial extraction of C-protein from rat skinned cardiac myocytes and rabbit skeletal muscle fibers. J Gen Physiol 97: 1141-1163, 1991.
9. Koretz JF. Effects of C-protein on synthetic myosin filament structure. Biophys J 27: 433-446, 1979.
10. Kunst G, Kress KR, Gruen M, Uttenweiler D, Gautel M, and Fink RH. Myosin binding protein C, a phosphorylation-dependent force regulator in muscle that controls the attachment of myosin heads by its interaction with myosin, S2. Circ Res 86: 51-58, 2000.
11. Levine RJC, Weisberg A, Kulikovskaya I, McClellan G, and Winegrad S. Multiple structures of thick filaments in resting cardiac muscle and their influence on cross bridge interactions. Biophys J 81: 1070-1082, 2001.
12. Lin LE, McClellan G, Weisberg A, and Winegrad S. Physiological basis for variation in the contractile properties of isolated rat heart. J Physiol 441: 73-79, 1991.
13. Lin Z, Lu MH, Schultheiss T, Choi J, Holtzer S, DiLuulo C, Fischman DA, and Holtzer H. Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: evidence for a conserved myoblast differentiation program in skeletal muscle. Cell Motil Cytoskeleton 29: 1-19, 1994.
14. Matsubara I. X-ray diffraction studies of the heart. Annu Rev Biophys Bioeng 9: 81-105, 1980.
15. McClellan G, Kulikovskaya I, and Winegrad S. Structural and functional responses of the contractile proteins to changes in calcium concentration in the heart. Biophys J 81: 1083-1092, 2001.
16. McClellan G, Weisberg A, and Winegrad S. cAMP can raise or lower cardiac actomyosin ATPase activity depending on alpha adrenergic activity. Am J Physiol Heart Circ Physiol 267: H431-H442, 1994.
17. Offer G, Moos C, and Starr R. A new protein of the thick filaments of vertebrate skeletal myofibrils. Extraction, purification and characterization. J Mol Biol 74: 653-676, 1973.
18. Rhee D, Sanger JM, and Sanger JW. The premyofibril: evidence for its role in myofibrillogenesis. Cell Motil Cytoskeleton 28: 1-24, 1994.
19. Rottbauer W, Gautel M, Zehelein J, Labeit S, Franz WM, Fischer C, Vollrath B, Mall G, Dietz R, Kubler W, and Katus HA. Novel splice donor site mutation in the cardiac myosin-binding protein C gene in familial hypertrophic cardiomyopathy. Characterization of cardiac transcript and protein. J Clin Invest 100: 475-482, 1997.
20. Seiler SH, Fischman DA, and Leinwand LA. Modulation of myosin filament organization by C protein family members. Mol Biol Cell 7: 113-127, 1996.
21. Watkins H, Conner D, Thierfelder L, Jarcho JA, MacCrea C, McKenna WJ, Maron BJ, Seidman JG, and Seidman CE. Mutations in the cardiac myosin-binding protein C on chromosome 11 cause familial hypertrophic cardiomyopathy. Nat Genet 11: 433-438, 1995.
22. Weisberg A and Winegrad S. Alteration in myosin cross bridges by phosphorylation of myosin-binding protein C in cardiac muscle. Proc Natl Acad Sci USA 93: 8999-9003, 1996.
23. Weisberg A and Winegrad S. Relation between cross bridge structure and actomyosin ATPase activity in rat heart. Circ Res 83: 60-72, 1998.
24. Yang Q, Saribe A, Osinska H, Hewitt TE, Klevitsky R, and Robbins J. A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy J. Clin Investig 102: 1292-1300, 1998.