Effect of Gymnema montanum on blood glucose, plasma insulin, and carbohydrate metabolic enzymes in alloxan-induced diabetic rats

Journal of Medicinal Food

Volumn 6, Issue 1, 2003, Pages 43-49

  Ananthan, Rajendran ^a   Latha, Muniappan ^b   Pari, Leelavinothan ^b   Ramkumar, Kunga Mohan ^b   Baskar, Chokkanna Gounder ^a   Bai, Vengatesh Narmatha ^a  

^a BHARATHIAR UNIVERSITY   (India)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; GLIBENCLAMIDE; GLUCOSE; GYMNEMA MONTANUM EXTRACT; INSULIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG EFFICACY; GLUCOSE BLOOD LEVEL; GYMNEMA MONTANUM; INSULIN BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; RAT;

ANIMALIA; GYMNEMA;

EID: 0037951503     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/109662003765184732     Document Type: Article

References (33)

1. American Diabetes Association: Clinical practice recommendations. Diabetes Care 2002;25:S1-S147.
2. Tiwari AK, Madhusudana Rao J: Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr Sci 2002;83:30-38.
3. Marx J: Unravelling the causes of diabetes. Science 2002;296:686-689.
4. Rang HP, Dale MM: The Endocrine System Pharmacology, 2nd ed. Longman, Harlow, London, 1991, pp 504-508.
5. Gupta D, Raju J, Jaya Prakash R, Baquer NZ: Changes in the lipid profile, lipogenic and related enzymes in the liver of experimental diabetic rats: effect of insulin and vanadate. Diabetes Res Clin Pract 1999;46:1-7.
6. Sochor M, Baquer NZ, McLean P: Glucose underutilization in diabetes: Comparative studies on the changes in the activities of enzymes of glucose metabolism in rat kidney and liver. Mol Physiol 1985;7: 51-68.
7. Warier PK: Eugenia jambolana Linn. In: Indian Medicinal Plants. (Warier PK, Nambiar VPK, Ramankutty C, eds.). Orient Longman, Madras, 1995, pp 48-51.
8. Srivastava Y, Bhat HV, Verma Y, Venkaidh K: Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-289.
9. Hooker JD: Asclepiadaceae. In: Hooker's Flora of British India, vol. 4. International Book Distributors, Dehradun, India, 1883, p 31.
10. Swarupanandan K: An analysis of physical basis and causes of rarity in the Asclepiadaceae. R Br Ss 1 of Kerala. The Proceedings of the Symposium on Rare, Endangered and Endemic Plants of the Western Ghats. 1991.
11. Niyonzima G, Vlietinck AJ: Hypoglycaemic activity of Spathodea campanulata stem bark decoction in mice. Phytother Res 1993;7:64-67.
12. Hossain, MZ, Shibib BA, Rahman R: Hypoglycemic effects of Coccinia indica: Inhibition of key gluconeogenic enzyme, glucose-6-phosphatase. Ind J Exp Biol 1992;10:418-420.
13. Al-Shamaony L, Al-Khazraji SM, Twaiji HA: Hypoglycaemic effect of Artemisia herba alba II: Effect of a valuable extract on some blood parameters in diabetic animals. J Ethnopharmacol 1994;43:167-171.
14. Gupta MP, Solis NG, Esposito M, Sanchez S: Hypoglycemic activity of Neurolaena lobata (L). R Br J Ethnopharmacol 1984;10:323-327.
15. Pari L, Uma Maheswari J: Antihyperglycemic activity of Musa sapientum flowers: Effect on lipid peroxidation in alloxan diabetic rats. Phytother Res 2000;14: 1-3.
16. Sasaki T, Masty S, Sonae A: Effect of acetic acid concentration on the colour reaction in the O-toluidine boric acid method for blood glucose estimation. Rinshbo Kagaku 1972;1:346-353.
17. Brandstrup N, Kirk JE, Bruni C: Determination of hexokinase in tissues. J Gerontol 1957;12:166-171.
18. Baginsky ES, Foa PP, Zak B: Glucose-6-phosphatase. In: Methods of Enzymatic Analysis, 2nd ed., vol. 2. (Bergymeyer HU, ed.). Academic Press, New York, 1974, pp 788-792.
19. Gancedo JM, Gancedo C: Fructose-1,6-diphosphatase, phospho-fructokinase and glucose-6-phosphate dehydrogenase from fermenting and non-fermenting yeasts. Arch Microbiol 1971;76:132-138.
20. Fiske CH, Subbarow J: The colorimetric determination of phosphorus. J Biol Chem 1925;66:375-400.
21. Ellis HA, Kirkman HN: A colorimetric method for assay of erythrocyte glucose-6-phosphatase dehydrogenase. Proc Soc Exp Biol Med 1961;106:607-609.
22. Morales MA, Jabbagy AJ, Tenenzi HP: Mutations affecting accumulation of glycogen. Neurospora News Lett 1973;20:24-25.
23. Lowry OH, Roesborough MJ, Farr AL, Randall RJ: Protein measurement with Folin-Phenol reagent. J Biol Chem 1951;193:265-275.
24. Duncan BD: Multiple range tests for correlated and heteroscedastic means. Biometrics 1957;13:359-364.
25. West KM: Hyperglycemia as a cause of long-term complications. In: Complications of Diabetes, 2nd ed. (Keen H, Jarret J, eds.). Edward Arnold, London, 1982, pp 3-18.
26. University Group Diabetes Program: A study of the effects of hypoglycaemia agents as vascular complication in patients with adult onset diabetes: Section V. Evaluation of phenformin therapy. Diabetes 1974; 24:65-184.
27. Knatterud G, Klimt CR, Levin ME, Jacobson ME, Goldner MG: Effect of hypoglycaemia agents on vascular complication in patients with adult onset diabetes: Section VIII. Mortality and selected non-fatal events with insulin treatment. JAMA 1978;240:37-42.
28. Murakami N, Murakami T, Kadoya M, Matsuda H, Yamahara J, Yoshikawa M: New hypoglycaemic constituents in 'gymnemic acid" from Gymnema sylvestere. Chem Pharm Bull 1996;44:469-471.
29. Welihinda J, Karunanayake EH: Extra-pancreatic effects of Eugenia jambolana in rats. J Ethnopharmacol 1986;17:247-255.
30. Lolitkar MM, Rao MRR: Pharmacology of a hypoglycaemic principle isolated from the fruits of Eugenia jambolana Linn. Ind J Pharm 1966;28:129-133.
31. Saxena AK, Srivastava P, Baquer NZ: Effects of vanadate on glycolytic enzymes and malic enzyme in insulin-dependent and independent tissues of diabetic rats. Eur J Pharmacol 1992;216:123-126.
32. Sheela GC, Augusti KT: Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn. Ind J Exp Biol 1992;30:523-526.
33. Baquer NZ, Gupta D, Raju J: Regulation of metabolic pathways in liver and kidney during experimental diabetes: Effects of antidiabetic compounds. Ind J Clin Biochem 1998;13:63-80.