Genetic analysis of a Theiler-like virus isolated from rats

Comparative Medicine

Volumn 53, Issue 2, 2003, Pages 191-196

  Ohsawa, Kazutaka ^a   Watanabe, Yoji ^a   Miyata, Hironori ^a   Sato, Hiroshi ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC RNA; NUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVIRUS; CONTROLLED STUDY; FEMALE; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; MALE; MENGO VIRUS; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; PREDICTION; PROTEIN SECONDARY STRUCTURE; RAT; RNA TRANSLATION; SEQUENCE HOMOLOGY; SPECIES DIFFERENTIATION; VIRUS GENE; VIRUS IDENTIFICATION; VIRUS ISOLATION; VIRUS MUTANT; VIRUS STRAIN;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARDIOVIRUS INFECTIONS; FEMALE; GENES, VIRAL; GENOME, VIRAL; IMMUNOBLOTTING; MALE; MICE; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; THEILOVIRUS;

EID: 0037947763     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Theiler, M. and S. Gard. 1940. Encephalomyelitis of mice. I. Characteristics and pathogenesis of the virus. J. Exp. Med. 72:49-67.
2. Daniels, J. B., A. M. Pappenheimer, and S. Richardson. 1952. Observations of encephalomyelitis of mice (DA strain). J. Exp. Med. 96:517-530.
3. Wroblewska, Z., D. H. Gilden, M. Wellish, L. B. Rorke, K. G. Warren, and J. S. Wolinsky. 1977. Virus-specific intracytoplasmic inclusions in mouse brain produced by a newly isolated strain of Theiler virus. Lab. Invest. 37:595-602.
4. Rozhon E. J., J. D. Kratochvil, and H. L. Lipton. 1983. Analysis of genetic variation in Theiler's virus during persistent infection in the mouse central nervous system. Virology 128:16-32.
5. Casals, J. Immunological characterization of Vilyuisk human encephalomyelitis virus. 1963. Nature 200:339-341.
6. McConnell, S. J., D. L. Huxsoll, F. M. Garner, R. O. Spertzel, A. R. Warner, Jr., and R. H. Yager. 1964. Isolation and characterization of a neurotropic agent (MHG virus) from adult rats. Exp. Biol. Med. 115:362-367.
7. Pritchard, A. E., T. Strom, and H. L. Lipton. 1992. Nucleotide sequence identifies Vilyuisk virus as a divergent Theiler's virus. Virol. 191:469-472.
8. Jacoby, R. O. and J. R. Lindsey. 1998. Risks of infection among laboratory rats and mice at major biomedical research institutions. ILAR J. 39:266-271.
9. Nicklas, W., P. Baneux, R. Boot, T. Decelle, A. A. Deeny, M. Fumanelli, B. Illgen-Wilcke. 2002. Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab. Anim. 36:20-42.
10. Ohsawa, K., Y. Watanabe, H. Miyata, and H. Sato. 1998. Genetic analysis of TMEV-like virus isolated from rats: nucleic acid characterization of 3-D protein region. Lab. Anim. Sci. (Abstr.) 48:418-419.
11. Miyata, H. and H. Sato. 1990. Theiler's murine encephalomyelitis virus-characterization of newly isolated viruses from Japanese mouse colonies. Exp. Anim. 39:539-548.
12. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
13. Puissant, C. and L. M. Houdebine. 1990. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques 8:148-149.
14. Kumar, S., K. Tamura, I. B. Jakobsen, and M. Nei. 2001. MEGA2: molecular evolutionary genetics analysis software. Arizona State University, Tempe, Ariz.
15. Hemelt, I. E., D. L. Huxsoll, and A. R. Warner Jr. 1974. Comparison of MHG virus with mouse encephalomyelitis viruses. Lab. Anim. Sci. 24:523-529.
16. Lipton, H. L., A. Friedmann, P. Sethi, and J. R. Crowther. 1983. Characterization of Vilyuisk virus as a picornavirus. J. Med. Virol. 12:195-203.
17. Kong, W. P. and R. P. Roos. 1991. Alternative translation initiation site in the DA strain of Theiler's murine encephalomyelitis virus. J. Virol. 65:3395-3399.
18. Chen, H.-H., W. P. Kong, L. Zhang, P. L. Ward, and R. P. Roos. 1995. A picornaviral protein synthesized out of frame with the polyprotein plays a key role in a virus-induced immune-mediated demyelinating disease. Nature Med. 1:927-931.
19. Ghadge, G. D. L., S. Ma, J. Sato, J. Kim, and R. P. Roos. 1998. A protein critical for a Theiler's virus-induced immune system-mediated demyelinating disease has a cell type-specific antiapoptotic effect and a key role in virus persistence. J. Virol. 72:8605-8612.
20. Obuchi, M., J. Yamamoto, T. Odagiri, M. N. Uddin, H. Iizuka, Y. Ohara. 2000. L* protein of Theiler's murine encephalomyelitis virus is required for virus growth in a murine macrophage-like cell line. J. Virol. 74:4898-4901.
21. Le, S. Y., A. Siddiqui, and J. V. Maizel, Jr. 1996. A common structural core in the internal ribosome entry sites of picornavirus, hepatitis C virus, and pestivirus. Virus Genes 12:135-147.