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1
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0027422191
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Mortality and morbidity after hip fractures
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PID: 8166806, COI: 1:STN:280:DyaK2c7gvVartw%3D%3D
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Keene GS, Parker MJ, Pryor GA: Mortality and morbidity after hip fractures. BMJ 1993, 307:1248–1250.
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BMJ
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Keene, G.S.1
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2
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0029800194
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Vertebral fracture and other predictors of physical impairment and health care utilization
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Huang C, Ross PD, Wasnich RD: Vertebral fracture and other predictors of physical impairment and health care utilization. Arch Intern Med 2003, 156:2469–2475. DOI: 10.1001/archinte.156.21.2469
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Arch Intern Med
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Huang, C.1
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Wasnich, R.D.3
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3
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0029904225
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Vertebral fractures and other predictors of back pain among older women
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Huang C, Ross PD, Wasnich RD: Vertebral fractures and other predictors of back pain among older women. J Bone Miner Res 2003, 11:1026–1032.
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J Bone Miner Res
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Huang, C.1
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Wasnich, R.D.3
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4
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0033550968
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Mortality after all major types of osteoporotic fracture in men and women: an observational study
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PID: 10093980, COI: 1:STN:280:DyaK1M7ptFOlug%3D%3D, A study from Australia that shows that fractures are associated with increased mortality compared with the general population; the mortality men with fractures is higher than women with fractures
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Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA: Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 1999, 353:878–882. A study from Australia that shows that fractures are associated with increased mortality compared with the general population; the mortality in men with fractures is higher than in women with fractures. DOI: 10.1016/S0140-6736(98)09075-8
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Lancet
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Center, J.R.1
Nguyen, T.V.2
Schneider, D.3
Sambrook, P.N.4
Eisman, J.A.5
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5
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-
0034022117
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Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group
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PID: 10733048, COI: 1:STN:280:DC%2BD3c7psFWrtA%3D%3D
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Ensrud KE, Thompson DE, Cauley JA, et al.: Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group. J Am Geriatr Soc 2000, 48:241–249.
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J Am Geriatr Soc
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Ensrud, K.E.1
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Cauley, J.A.3
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6
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0034739277
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Alendronate for the treatment of osteoporosis in men
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PID: 10979796, COI: 1:CAS:528:DC%2BD3cXmsFSqs7k%3D, The first randomized, placebo-controlled intervention trial men with osteoporosis that shows fracture risk reduction with alendronate of similar magnitude to fracture risk reduction women
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Orwoll E, Ettinger M, Weiss S, et al.: Alendronate for the treatment of osteoporosis in men. N Engl J Med 2000, 343:604–610. The first randomized, placebo-controlled intervention trial in men with osteoporosis that shows fracture risk reduction with alendronate of similar magnitude to fracture risk reduction in women. DOI: 10.1056/NEJM200008313430902
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N Engl J Med
, vol.343
, pp. 604-610
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Orwoll, E.1
Ettinger, M.2
Weiss, S.3
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7
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0004851872
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Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
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Black DM, Cummings SR, Karpf DB, et al.: Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 2003, 348:1535–1541. DOI: 10.1016/S0140-6736(96)07088-2
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Lancet
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Black, D.M.1
Cummings, S.R.2
Karpf, D.B.3
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8
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0032896590
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Multinational, placebocontrolled, randomized trial of the effects of alendronate on bone density and fracture risk in postmenopausal women with low bone mass: results of the FOSIT study. Foxamax International Trial Study Group
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PID: 10550467, COI: 1:CAS:528:DyaK1MXkt1CktrY%3D, Randomized, placebo-controlled trial of alendronate women with low BMD showing significant efficacy reducing incidence of nonvertebral fractures
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Pols HA, Felsenberg D, Hanley DA, et al.: Multinational, placebocontrolled, randomized trial of the effects of alendronate on bone density and fracture risk in postmenopausal women with low bone mass: results of the FOSIT study. Foxamax International Trial Study Group. Osteoporos Int 1999, 9:461–468. Randomized, placebo-controlled trial of alendronate in women with low BMD showing significant efficacy in reducing incidence of nonvertebral fractures. DOI: 10.1007/PL00004171
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(1999)
Osteoporos Int
, vol.9
, pp. 461-468
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Pols, H.A.1
Felsenberg, D.2
Hanley, D.A.3
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9
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0032583492
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Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial
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PID: 9875874, COI: 1:CAS:528:DyaK1MXjsVWruw%3D%3D
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Cummings SR, Black DM, Thompson DE, et al.: Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA 1998, 280:2077–2082. DOI: 10.1001/jama.280.24.2077
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JAMA
, vol.280
, pp. 2077-2082
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Cummings, S.R.1
Black, D.M.2
Thompson, D.E.3
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10
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0028851590
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Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group
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PID: 7477143, COI: 1:CAS:528:DyaK28XkslehtA%3D%3D
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Liberman UA, Weiss SR, Broll J, et al.: Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group. N Engl J Med 1995, 333:1437–1443. DOI: 10.1056/NEJM199511303332201
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Liberman, U.A.1
Weiss, S.R.2
Broll, J.3
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11
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0033552255
-
Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group
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PID: 10527181, COI: 1:CAS:528:DyaK1MXmvFansr0%3D, A double blind, randomized, placebo-controlled trial that shows that risedronate can reduce the incidence of vertebral and nonvertebral fractures women with multiple vertebral fractures
-
Harris ST, Watts NB, Genant HK, et al.: Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 1999, 282:1344–1352. A double blind, randomized, placebo-controlled trial that shows that risedronate can reduce the incidence of vertebral and nonvertebral fractures in women with multiple vertebral fractures. DOI: 10.1001/jama.282.14.1344
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(1999)
JAMA
, vol.282
, pp. 1344-1352
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Harris, S.T.1
Watts, N.B.2
Genant, H.K.3
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12
-
-
12944291524
-
Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
-
PID: 10663363, COI: 1:CAS:528:DC%2BD3cXhvFGgsr0%3D, Randomized, placebo-controlled trial that shows that risedronate can reduce the incidence of vertebral fracture women with osteoporosis
-
Reginster J, Minne HW, Sorensen OH, et al.: Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group. Osteoporos Int 2000, 11:83–91. Randomized, placebo-controlled trial that shows that risedronate can reduce the incidence of vertebral fracture in women with osteoporosis. DOI: 10.1007/s001980050010
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Osteoporos Int
, vol.11
, pp. 83-91
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Reginster, J.1
Minne, H.W.2
Sorensen, O.H.3
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13
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0035253489
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Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group
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PID: 11172164, COI: 1:CAS:528:DC%2BD3MXht1Wlu7g%3D, The first randomized, placebo-controlled trial of bisphosphonate therapy women with osteoporosis, with hip fracture reduction as the primary endpoint. Showed that, if risedronate was targeted on basis of low BMD, bisphosphonate therapy could reduce hip fracture incidence. Hip fracture reduction is not seen if treatment is targeted on basis of non-BMD fracture risk factors
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McClung MR, Geusens P, Miller PD, et al.: Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med 2001, 344:333–340. The first randomized, placebo-controlled trial of bisphosphonate therapy in women with osteoporosis, with hip fracture reduction as the primary endpoint. Showed that, if risedronate was targeted on basis of low BMD, bisphosphonate therapy could reduce hip fracture incidence. Hip fracture reduction is not seen if treatment is targeted on basis of non-BMD fracture risk factors. DOI: 10.1056/NEJM200102013440503
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(2001)
N Engl J Med
, vol.344
, pp. 333-340
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McClung, M.R.1
Geusens, P.2
Miller, P.D.3
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14
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0025334778
-
Intermittent cyclical etidronate treatment of postmenopausal osteoporosis
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PID: 2113611, COI: 1:STN:280:DyaK3c3psVyluw%3D%3D
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Watts NB, Harris ST, Genant HK, et al.: Intermittent cyclical etidronate treatment of postmenopausal osteoporosis. N Engl J Med 1990, 323:73–79. DOI: 10.1056/NEJM199007123230201
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Watts, N.B.1
Harris, S.T.2
Genant, H.K.3
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15
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0033581212
-
Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
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PID: 10517716, COI: 1:CAS:528:DyaK1MXlvVKqurg%3D, Randomized, placebo-controlled trial of the first selective estrogen receptor modulator women with osteoporotic fractures. Fracture efficacy is restricted to vertebral fracture risk reduction
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Ettinger B, Black DM, Mitlak BH, et al.: Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. JAMA 1999, 282:637–645. Randomized, placebo-controlled trial of the first selective estrogen receptor modulator in women with osteoporotic fractures. Fracture efficacy is restricted to vertebral fracture risk reduction. DOI: 10.1001/jama.282.7.637
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(1999)
JAMA
, vol.282
, pp. 637-645
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Ettinger, B.1
Black, D.M.2
Mitlak, B.H.3
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16
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0033829969
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A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study
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COI: 1:CAS:528:DC%2BD3cXms1Wku70%3D
-
Chesnut CH III, Silverman S, Andriano K, et al.: A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group. Am J Med 2000, 109:267–276.
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PROOF Study Group. Am J Med
, vol.109
, pp. 267-276
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Chesnut, C.H.1
Silverman, S.2
Andriano, K.3
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17
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0030873404
-
Guidelines for diagnosis and management of osteoporosis. The European Foundation for Osteoporosis and Bone Disease
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PID: 9373575, COI: 1:STN:280:DyaK1c%2FktV2jtA%3D%3D
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Kanis JA, Delmas P, Burckhardt P, et al.: Guidelines for diagnosis and management of osteoporosis. The European Foundation for Osteoporosis and Bone Disease. Osteoporos Int 1997, 7:390–406. DOI: 10.1007/BF01623782
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Osteoporos Int
, vol.7
, pp. 390-406
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Kanis, J.A.1
Delmas, P.2
Burckhardt, P.3
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19
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0034022318
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Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis
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PID: 10780864, COI: 1:STN:280:DC%2BD3c3ktFOktA%3D%3D
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Klotzbuecher CM, Ross PD, Landsman PB, et al.: Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 2000, 15:721–739. DOI: 10.1359/jbmr.2000.15.4.721
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J Bone Miner Res
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Klotzbuecher, C.M.1
Ross, P.D.2
Landsman, P.B.3
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20
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0036342982
-
Does a Fracture at one site predict later fractures at other sites? A British Cohort Study
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PID: 12181620, A study that gives further insight into the risk of fractures at any site after a previous fracture at any site. This increased fracture risk holds true postmenopausal women, premenopausal women, and men. Provides useful actual 5-year fracture risks after fracture at different ages
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van Staa TP, Leufkens HG, Cooper C: Does a Fracture at one site predict later fractures at other sites? A British Cohort Study. Osteoporos Int 2002, 13:624–629. A study that gives further insight into the risk of fractures at any site after a previous fracture at any site. This increased fracture risk holds true in postmenopausal women, premenopausal women, and in men. Provides useful actual 5-year fracture risks after fracture at different ages. DOI: 10.1007/s001980200084
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(2002)
Osteoporos Int
, vol.13
, pp. 624-629
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van Staa, T.P.1
Leufkens, H.G.2
Cooper, C.3
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21
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0036250406
-
Fractures before menopause: a red flag for physicians
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PID: 12030549, COI: 1:STN:280:DC%2BD383ptVCitw%3D%3D
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Hosmer WD, Genant HK, Browner WS: Fractures before menopause: a red flag for physicians. Osteoporos Int 2002, 13:337–341. DOI: 10.1007/s001980200035
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(2002)
Osteoporos Int
, vol.13
, pp. 337-341
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Hosmer, W.D.1
Genant, H.K.2
Browner, W.S.3
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22
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0037074201
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Fractures between the ages of 20 and 50 years increase women’s risk of subsequent fractures
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PID: 11784217
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Wu F, Mason B, Horne A, et al.: Fractures between the ages of 20 and 50 years increase women’s risk of subsequent fractures. Arch Intern Med 2002, 162:33–36. DOI: 10.1001/archinte.162.1.33
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Arch Intern Med
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Wu, F.1
Mason, B.2
Horne, A.3
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0032862178
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Vertebral fractures predict subsequent fractures
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PID: 10525713
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Melton LJ III, Atkinson EJ, Cooper C, et al.: Vertebral fractures predict subsequent fractures. Osteoporos Int 1999, 10:214–221. DOI: 10.1007/s001980050218
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, vol.10
, pp. 214-221
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Melton, L.J.1
Atkinson, E.J.2
Cooper, C.3
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24
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0028262189
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Risk of hip fracture in women with vertebral fracture
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PID: 8053387, COI: 1:STN:280:DyaK2czjtVeqsA%3D%3D
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Kotowicz MA, Melton LJ III, Cooper C, et al.: Risk of hip fracture in women with vertebral fracture. J Bone Miner Res 1994, 9:599–605. DOI: 10.1002/jbmr.5650090503
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J Bone Miner Res
, vol.9
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Kotowicz, M.A.1
Melton, L.J.2
Cooper, C.3
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25
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0035086120
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Prevalent vertebral deformity predicts incident hip though not distal forearm fracture: results from the European Prospective Osteoporosis Study
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PID: 11303719, COI: 1:STN:280:DC%2BD3M3oslaltg%3D%3D
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Ismail AA, Cockerill W, Cooper C, et al.: Prevalent vertebral deformity predicts incident hip though not distal forearm fracture: results from the European Prospective Osteoporosis Study. Osteoporos Int 2001, 12:85–90. DOI: 10.1007/s001980170138
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Osteoporos Int
, vol.12
, pp. 85-90
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Ismail, A.A.1
Cockerill, W.2
Cooper, C.3
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26
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0035071033
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Acute and long-term increase in fracture risk after hospitalization for vertebral fracture
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PID: 11315239, COI: 1:STN:280:DC%2BD3M3oslKrsA%3D%3D, A study that highlights the early increased risk of fractures seen after discharge after vertebral fracture requiring hospitalization. reality, few patients with vertebral fractures are admitted, but they are at very high risk of early, further fractures
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Johnell O, Oden A, Caulin F, Kanis JA: Acute and long-term increase in fracture risk after hospitalization for vertebral fracture. Osteoporos Int 2001, 12:207–214. A study that highlights the early increased risk of fractures seen after discharge after vertebral fracture requiring hospitalization. In reality, few patients with vertebral fractures are admitted, but they are at very high risk of early, further fractures. DOI: 10.1007/s001980170131
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(2001)
Osteoporos Int
, vol.12
, pp. 207-214
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Johnell, O.1
Oden, A.2
Caulin, F.3
Kanis, J.A.4
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27
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17344374995
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Epidemiology of vertebral osteoporosis
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PID: 1385718
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Kanis JA, McCloskey EV: Epidemiology of vertebral osteoporosis. Bone 1992, 13(suppl):S1-S10. DOI: 10.1016/8756-3282(92)90189-4
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(1992)
Bone
, vol.13
, pp. S1-S10
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Kanis, J.A.1
McCloskey, E.V.2
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28
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0035086805
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Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women
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PID: 11305078, COI: 1:STN:280:DC%2BD3M3ivFKhtg%3D%3D, Important study that adds useful information about lifetime fracture risk
-
Doherty DA, Sanders KM, Kotowicz MA, Prince RL: Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women. Osteoporos Int 2001, 12:16–23. Important study that adds useful information about lifetime fracture risk. DOI: 10.1007/s001980170152
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(2001)
Osteoporos Int
, vol.12
, pp. 16-23
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Doherty, D.A.1
Sanders, K.M.2
Kotowicz, M.A.3
Prince, R.L.4
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29
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0036147146
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Usefulness of bone densitometry in postmenopausal women with clinically diagnosed vertebral fractures
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PID: 11779765, COI: 1:STN:280:DC%2BD38%2FltlGrtg%3D%3D, Study confirming the high prevalence of osteoporosis patients presenting with clinical vertebral fractures
-
Nolla JM, Gomez-Vaquero C, Fiter J, et al.: Usefulness of bone densitometry in postmenopausal women with clinically diagnosed vertebral fractures. Ann Rheum Dis 2002, 61:73–75. Study confirming the high prevalence of osteoporosis in patients presenting with clinical vertebral fractures. DOI: 10.1136/ard.61.1.73
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Ann Rheum Dis
, vol.61
, pp. 73-75
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Nolla, J.M.1
Gomez-Vaquero, C.2
Fiter, J.3
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30
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0037169899
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Osteoporosis intervention following distal forearm fractures
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PID: 11863474
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Cuddihy MT, Gabriel SE, Crowson CS, et al.: Osteoporosis intervention following distal forearm fractures. Arch Intern Med 2002, 162:421–426. DOI: 10.1001/archinte.162.4.421
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Arch Intern Med
, vol.162
, pp. 421-426
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Cuddihy, M.T.1
Gabriel, S.E.2
Crowson, C.S.3
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31
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0031819691
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Prescribing by general practitioners after an osteoporotic fracture
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PID: 9771215, COI: 1:STN:280:DyaK1cvksVWmtg%3D%3D
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Torgerson DJ, Dolan P: Prescribing by general practitioners after an osteoporotic fracture. Ann Rheum Dis 1998, 57:378–379. DOI: 10.1136/ard.57.6.378
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Ann Rheum Dis
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Torgerson, D.J.1
Dolan, P.2
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32
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0036120358
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Evaluation of osteoporosis treatment in seniors after hip fracture
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PID: 11991439, COI: 1:STN:280:DC%2BD383ltVGitw%3D%3D
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Juby AG, Geus-Wenceslau CM: Evaluation of osteoporosis treatment in seniors after hip fracture. Osteoporos Int 2002, 13:205–210. DOI: 10.1007/s001980200015
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Osteoporos Int
, vol.13
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Juby, A.G.1
Geus-Wenceslau, C.M.2
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A 28-month audit of the efficacy of the fracture liaison service in offering secondary prevention for patients with osteoporotic fractures [abstract]
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McLellan AR, Fraser M: A 28-month audit of the efficacy of the fracture liaison service in offering secondary prevention for patients with osteoporotic fractures [abstract]. J Bone Miner Res 2002, 17:S385.
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, vol.17
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McLellan, A.R.1
Fraser, M.2
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34
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0026691295
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Treatment of postmenopausal osteoporosis with transdermal estrogen
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PID: 1534476, COI: 1:STN:280:DyaK383otFaltA%3D%3D
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Lufkin EG, Wahner HW, O’Fallon WM, et al.: Treatment of postmenopausal osteoporosis with transdermal estrogen. Ann Intern Med 1992, 117:1–9.
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Ann Intern Med
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Lufkin, E.G.1
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O’Fallon, W.M.3
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35
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0034097152
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Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group
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PID: 10746426, COI: 1:CAS:528:DC%2BD3cXitVCns7g%3D
-
Schnitzer T, Bone HG, Crepaldi G, et al.: Therapeutic equivalence of alendronate 70 mg once-weekly and alendronate 10 mg daily in the treatment of osteoporosis. Alendronate Once-Weekly Study Group. Aging 2000, 12:1–12.
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Aging
, vol.12
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Schnitzer, T.1
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36
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0037125379
-
Risks and benefits of estrogen plus progestin in healthy postmenopausal women
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Study that defines the risks and benefits of hormone replacement therapy use normal, healthy postmenopausal women. Confirms that, even normal women, 5 years of hormone replacement can reduce the incidence of hip and other fractures. Overall, with 5 years of hormone replacement therapy, the risks may outweigh the benefits
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Writing Group for the Women’s Health Initiative Investigators: Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 2002, 288:321–333. Study that defines the risks and benefits of hormone replacement therapy use in normal, healthy postmenopausal women. Confirms that, even in normal women, 5 years of hormone replacement can reduce the incidence of hip and other fractures. Overall, with 5 years of hormone replacement therapy, the risks may outweigh the benefits. DOI: 10.1001/jama.288.3.321
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(2002)
JAMA
, vol.288
, pp. 321-333
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37
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0028295830
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Effect of calcium and cholecalciferol treatment for three years on hip fractures in elderly women
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PID: 8173430, COI: 1:STN:280:DyaK2c3islKnuw%3D%3D
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Chapuy MC, Arlot ME, Delmas PD, Meunier PJ: Effect of calcium and cholecalciferol treatment for three years on hip fractures in elderly women. BMJ 1994, 308:1081–1082.
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38
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0030678609
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Hip fracture in elderly men: prognostic factors and outcomes
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