Enantioselective synthesis of clavepictine analogues and evaluation of their cytotoxic activity

European Journal of Organic Chemistry

Volumn , Issue 11, 2003, Pages 2062-2070

  Agami, Claude ^a   Couty, François ^b   Evano, Gwilherm ^a   Darro, Francis ^c   Kiss, Robert ^c  

^a SORBONNE UNIVERSITÉ   (France)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Cytotoxic compounds; Human cancer cell lines; Iminium ions; Quinolizidines

Indexed keywords

3 HYDROXY 4 METHYL 6 PHENYLETHYNYLOCTAHYDROQUINOLIZIDINE; 6 (DEC 1 ENYL) 3 HYDROXY 4 METHYLOCTAHYDROQUINOLIZIDINE; 6 (DEC 3 EN 1 YNYL) 3 HYDROXY 4 METHYLOCTAHYDROQUINOLIZIDINE; 6 DECYL 3 HYDROXY 4 METHYLOCTAHYDROQUINOLIZIDINE; 6 ETHYNYL 3 HYDROXY 6 METHYLOCTAHYDROQUINOLIZIDINE; 7 HYDROXY 6 METHYLOCTAHYDROQUINOLIZIDINE 4 CARBONITRILE; ALKALOID DERIVATIVE; AMINONITRILE; CLAVEPICTINE DERIVATIVE; CYTOTOXIC AGENT; DOXORUBICIN; ETOPOSIDE; IRINOTECAN; NITRILE; OXAZOLIDINE DERIVATIVE; QUINOLIZIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CLAVELINA PICTA; COLON CANCER; COLORIMETRY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; LUNG CANCER; STEREOCHEMISTRY; UROCHORDATA;

EID: 0037934623     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ejoc.200300057     Document Type: Article

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