Determinants of symptoms and exercise capacity in aortic stenosis: A comparison of resting haemodynamics and valve compliance during dobutamine stress

European Heart Journal

Volumn 24, Issue 13, 2003, Pages 1254-1263

  Das, Paul ^a,c   Rimington, Helen ^a   Smeeton, Nigel ^b   Chambers, John ^a  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c WYTHENSHAWE HOSPITAL   (United Kingdom)

Author keywords

Aortic stenosis; Stress echocardiography; Valve compliance

Indexed keywords

DOBUTAMINE;

ADULT; AGED; AORTA STENOSIS; AORTA VALVE; ARTICLE; ECHOCARDIOGRAPHY; EXERCISE; EXERCISE TEST; FEMALE; HEART MUSCLE COMPLIANCE; HEART VALVE; HEART VENTRICLE FUNCTION; HEMODYNAMICS; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REST; TREADMILL; WORKLOAD;

ADULT; AGED; AGED, 80 AND OVER; AORTIC VALVE STENOSIS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPLIANCE; ECHOCARDIOGRAPHY, STRESS; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART RATE; HUMANS; MALE; MIDDLE AGED; REST; STROKE VOLUME;

EID: 0037929695     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-668X(03)00235-5     Document Type: Article

References (28)

1. Otto CM. Valvular aortic stenosis: which measure of severity is best? Am Heart J 1998;136:940-2.
2. Otto CM. The difficulties in assessing patients with moderate aortic stenosis. Heart 1999;82:5-6.
3. Lester SJ, Heilbron B, Gin K et al. The natural history and rate of progression of aortic stenosis. Chest 1998; 113:1109-14.
4. Chambers JB, Sprigings DC, Cochrane T et al. Continuity equation and Gorlin formula compared with directly observed orifice area in native and prosthetic aortic valves. Br Heart J 1992;67:193-9.
5. Voelker W, Reul H, Nienhaus G et al. Comparison of valvular resistance, stroke work loss, and Gorlin valve area for the quantification of aortic stenosis. Circulation 1995; 91:1196-204.
6. Shively BK, Charlton GA, Crawford MH et al. Flow dependence of valve area in aortic stenosis: relation to valve morphology. JACC 1998;31:654-60.
7. Bermejo J, Garcia-Fernandez MA, Torrecilla EG et al. Effects of dobutamine on Doppler echocardiographic indexes of aortic stenosis. JACC 1996;28:1206-13.
8. Lin SS, Roger VL, Pascoe R et al. Dobutamine stress Doppler hemodynamics in patients with aortic stenosis: feasibility, safety and surgical considerations. Am Heart J 1998; 136:1010-6.
9. Otto CM, Burwash IG, Legget ME et al. Prospective study of asymptomatic valvular aortic stenosis. Clinical, echocardiographic, and exercise predictors of outcome. Circulation 1997;95:2262-70.
10. Rosenhek R, Binder T, Porenta G et al. Predictors of outcome in severe, asymptomatic aortic stenosis. N Engl J Med 2000;343:611-7.
11. Otto CM, Pearlman AS, Kraft CD et al. Physiologic changes with maximal exercise in asymptomatic valvular aortic stenosis assessed by Doppler echocardiography. J Am Coll Cardiol 1992;20:1160-7.
12. Amoto MCM, Moffa PJ, Werner KE et al. Treatment decision in asymptomatic aortic stenosis: the role of exercise testing. Heart 2001;86:381-6.
13. Sahn DJ, De Maria A, Kisslo J. The Committee on M-mode Standardization of the American Society of Echocardiography: recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:1072-81.
14. Gibbons RJ. ACC/AHA Guidelines for exercise testing. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Exercise Testing). JACC 1997;30:260-315.
15. Bruce RA. Exercise testing methods and interpretation. Adv Cardiol 1978;24:6-15.
16. Iung B, Gohlke-Bärwolf C, Tornos P et al. on behalf of the ESC Working Group on Valvular Heart Disease Recommendations on the management of the asymptomatic patient with valvular heart disease. Eur Heart J 2002;23:1253-66 doi:10.1053/euhj.2002.3320.
17. deFilippi CR, DuWayne LW, Brickner ME et al. Usefulness of dobutamine echocardiography in distinguishing severe from nonsevere valvular aortic stenosis in patients with depressed Left ventricular function and low transvalvular gradients. Am J Cordial 1995;75:192-4.
18. Monin J, Monchi M, Gest V et al. Aortic stenosis with severe left ventricular dysfunction and low transvalvular pressure gradients. Risk stratification by low-dose dobutamine echocardiography. JACC 2001;37:2101-7.
19. Bermejo J, Antoranz JC, Garcia-Fernandez MA et al. Flow dynamics of stenotic aortic valves assessed by signal processing of Doppler spectograms. Am J Cardiol 2000; 85:611-7.
20. Bermejo J, Antoranz JC, Burwash IG et al. In-vivo analysis of the instantaneous transvalvular pressure difference-flow relationship in aortic stenosis: implications of the unsteady fluid-dynamics for the clinical assessment of disease severity. J Heart Valve Dis 2002;11:557-66.
21. Sprigings DC, Chambers JB, Cochrane T et al. Ventricular stroke work loss: validation of a method of quantifying the severity of aortic stenosis and derivation of an orifice formula. JACC 1990;16:1608-14.
22. Tardif J, Rodrigues AG, Hardy JF et al. Simultaneous determination of aortic valve area by the Gorlin formula and by transoesophageal echocardiography under different transvalvular flow conditions. J Am Coll Cardiol 1997;29:1296-302.
23. Arsenault M, Masani N, Magni G et al. Variation of anatomic valve area during ejection in patients with valvular aortic stenosis evaluated by two-dimensional echocardiographic planimetry: comparison with traditional Doppler data. J Am Coll Cardiol 1998;32:1931-7.
24. Heinrich RS, Marcus RH, Ensley AE et al. Valve orifice area alone is an insufficient index of aortic stenosis severity: effects of the proximal and distal geometry on transaortic energy loss. J Heart Valve Dis 1999;8:509-15.
25. Otto CM, Pearlman AS, Gardner CL. Haemodynamic progression of aortic stenosis in adults assessed by Doppler echocardiography. JACC 1989;13:545-50.
26. Otto CM, Nishimura RA, Davis KB et al. Doppler echocardiographic findings in adults with severe symptomatic valvular aortic stenosis. Balloon Valvuloplasty Registry Echocardiographers. Am J Cardiol 1991;68:1477-84.
27. Takeda S, Rimington H, Chambers JB. The relation between transaortic pressure difference and flow during dobutamine stress echocardiography in patients with aortic stenosis. Heart 1999;82:11-4.
28. Silove ED, Vogel JHK, Grover RF. The pressure gradient in ventricular outflow obstruction: influence of peripheral resistance. Cardiovasc Res 1968;3:234-42.