Lerdelimumab: Prevention of corneal scarring

Drugs of the Future

Volumn 28, Issue 4, 2003, Pages 320-322

  Mealy, N E ^a   Bayes M ^a  

^a PROUS SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LERDELIMUMAB; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG ACTIVITY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG TOLERABILITY; EYE DISEASE; GLAUCOMA; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NONHUMAN; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; SCAR FORMATION; SIDE EFFECT; TRABECULECTOMY;

EID: 0037897494     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2003.028.04.726560     Document Type: Article

References (17)

1. 2 (CAT-152): From phage displayed antibody to clinical trials for reduction of scarring following glaucoma filtration surgery. Wound Repair Regen 2000, 8(5): A419.
2. 2 antibody (CAT- 152) as a new post-operative modulator of scarring after experimental glaucoma filtration surgery. Annu Meet Assoc Res Vision Ophthalmol (May 5-10, Fort Lauderdale) 2002, Abst 3332.
3. Elena, P.P., McFarlane, S., Glover, D.R., Amar, T., Caillaud, T. Ocular distribution of CAT-152 after a single subconjunctival injection in a pigmented rabbit model of glaucoma filtration surgery. Annu Meet Assoc Res Vision Ophthalmol (April 29-May 4, Fort Lauderdale) 2001, Abst.
4. 2 monoclonal antibody - a new modulator of wound healing in trabeculectomy: A randomized placebo controlled clinical study. Ophthalmology 2002, 109: 427-31.
5. 2 antibody (CAT-152) as a new modulator of wound healing in glaucoma filtration surgery: Longer term follow up data. Annu Meet Assoc Res Vision Ophthalmol (April 29-May 4, Fort Lauderdale) 2001, Abst.
6. 2 monoclonal antibody (CAT-152): A new modulator of wound healing following trabeculectomy. Invest Ophthalmol Visual Sci 2000, 41(4): Abst 3958.
7. 2 human monoclonal antibody as a novel agent to prevent scarring following phacotrabeculectomy. Annu Meet Assoc Res Vision Ophthalmol (May 5-10, Fort Lauderdale) 2002, Abst 3331.
8. Product pipeline. CAT-152 - treatment for scarring following glaucoma surgery. Cambridge Antibody Technology Web Site March 31, 2003.
9. 2. Annu Meet Asssoc Res Vision Ophthalmol (May 10-15, Fort Lauderdale) 1998, Abst 566.
10. 2 monoclonal antibody on in vitro human conjunctival fibroblast-mediated scarring response. Annu Meet Assoc Res Vision Ophthalmol (May 10-15, Fort Lauderdale) 1998, Abst 5115.
11. 2 human monoclonal antibody. Invest Ophthalmol Visual Sci 1999, 40(4): Abst 2030.
12. 2 mediated effects on human lens epithelial cells by the human monoclonal antibody CAT-152. Annu Meet Assoc Res Vision Ophthalmol (April 29-May 4, Fort Lauderdale) 2001, Abst.
13. 2 and EGF regulation of MMP-2 and -9 expression in the human lens capsular bag. Annu Meet Assoc Res Vision Ophthalmol (April 29-May 4, Fort Lauderdale) 2001, Abst.
14. 2 antagonist on fibrosis in the experimental diabetic rat kidney. Endocr Abstr 2001, 1: Abst P93.
15. 2 antibody attenuates fibrosis in the experimental diabetic rat kidney. J Endocrinol 2001, 170: 647-51.
16. 2-induced matrix modification and cell transdifferentiation in the human lens capsular bag. Invest Ophthalmol Vis Sci 2002, 43: 2301-8.
17. 2 exposure mediates long-term changes in the human lens capsular bag. Annu Meet Assoc Res Vision Ophthalmol (May 5-10, Fort Lauderdale) 2002, Abst 2984.