Direct coupling of thin-layer chromatography: With matrix-assisted laser desorption/ionization mass spectrometry

American Laboratory

Volumn 30, Issue 12, 1998, Pages 30-38

  Mehl, John T ^a   Nicola, Anthony J ^a   Isbell, Donna T ^c   Gusev, Arkady I ^a,d,e,f,g   Hercules, David M ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b Intl Assoc Environ Analyt C

^c Dept of Tech Sci Lit Services ^*  (United States)

^d ROHM AND HAAS COMPANY   (United States)

^e NATIONAL SCIENCE FOUNDATION   (United States)

^f Whatman Ltd   (United States)

^g PERKINELMER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIZATION; DESORPTION; IMAGING TECHNIQUES; IONIZATION; LASER APPLICATIONS; MASS SPECTROMETRY; OPTICAL RESOLVING POWER; SENSITIVITY ANALYSIS; SEPARATION; SOLVENT EXTRACTION;

ANALYTE EXTRACTION; MATRIX ASSISTED LASER DESORPTION IONIZATION; MULTIPHOTON IONIZATION;

THIN LAYER CHROMATOGRAPHY;

EID: 0037881793     PISSN: 00447749     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (11)

1. Busch KL. Thin layer chromatography coupled with mass spectrometry. In: Sherma J, Fried B, eds. Handbook of thin layer chromatography. New York: Marcel Dekker, 1991:183.
2. Hillenkamp F, Karas M, Beavis RC, Chait TC. Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers. Anal Chem 1991; 63(24):1193A-202A.
3. Gusev AI, Proctor A, Rabinovich YI, Hercules DM. Thin-layer chromatography combined with matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem 1995; 67(11):1805-14.
4. Gusev IA, Vasseur OJ, Proctor A, Sharkey AG, Hercules DM. Imaging of thin-layer chromatograms using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem 1995; 67(24):4565-70.
5. Isbell TD, Gusev AI, Taranenko NI, Chen CH, Hercules DM. Separation and detection of carcinogen-adducted oligonucleotides. Rap Commun Mass Spectrom (submitted).
6. Nicola AJ, Gusev AI, Hercules DM. Direct quantitative analysis from thin-layer chromatography plates using matrix-assisted laser desorption/ionization mass spectrometry. Appl Spectrosc 1996; 50(12):1479-82.
7. Gusev AI, Wilkinson WR, Proctor A. Hercules DM. Improvement of signal reproducibility and matrix/comatrix effects in MALDI analysis. Anal Chem 1995;67(6):1034-41.
8. Mehl JT, Gusev AI, Hercules DM. Coupling protocol for thin layer chromatography/matrix-assisted laser desorption ionization. Chromatographia 1997; 46:358-64.
9. Isbell TD, Gusev AI, Taranenko NI, Chen CH, Hercules DM. Analysis of nucleotides directly from TLC plates using MALDI-MS detection. Fresenius J Anal Chem (submitted).
10. Dreisewerd K, Schürenberg M, Karas M, Hillenkamp F. Influence of the laser intensity and spot size on the desorption of molecules and ions in matrix-assisted laser desorption/ionization with a uniform beam profile. Int J Mass Spectrom, Ion Processes 1995; 141:127-48.
11. Nicola AJ, Gusev AI, Proctor A, Jackson EK, Hercules DM. Application of the fast-evaporation sample preparation method for improving quantification of angiotensin II by matrix-assisted laser desorption. Rap Commun Mass Spectrom 1995; 9:1164-71.