Synthesis of spirodienones by intramolecular ipso-cyclization of N-methoxy-(4-halogenophenyl)amides using [hydroxy(tosyloxy)iodo]benzene in trifluoroethanol

Journal of Organic Chemistry

Volumn 68, Issue 13, 2003, Pages 5429-5432

  Miyazawa, Etsuko ^a   Sakamoto, Takeshi ^a   Kikugawa, Yasuo ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTRAMOLECULAR IPSO-CYCLIZATION;

IONS; MOLECULES; SYNTHESIS (CHEMICAL);

ORGANIC COMPOUNDS;

1 METHOXY 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; 1 METHOXY 7 METHYL 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; 1 OXO 2 METHOXY 3,4 DIHYDRO 2H ISOQUINOLINE 3 SPIRO 1' (CYCLOHEXA 2',5' DIEN 4' ONE); 6 CHLORO 1 METHOXY 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; 6 FLUORO 1 METHOXY 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; 6,7 DIFLUORO 1 METHOXY 1H QUINOLIN 2 ONE; 7 CHLORO 1 METHOXY 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; 7 FLUORO 1 METHOXY 1 AZASPIRO[4.5]DECA 6,9 DIENE 2,8 DIONE; [HYDROXY(TOSYLOXY)IODO]BENZENE; ALKADIENE; AMIDE; BENZENE DERIVATIVE; HALOGEN; IODINE DERIVATIVE; SPIRO COMPOUND; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ALKALOIDS; AMIDES; AZA COMPOUNDS; CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; HYDROCARBONS, HALOGENATED; MOLECULAR STRUCTURE; ORGANOPHOSPHORUS COMPOUNDS; SPIRO COMPOUNDS;

EID: 0037870758     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo034318w     Document Type: Article

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