-
1
-
-
0020071965
-
Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma
-
Filley WV. Holley KE, Kephart GM, Gleich GJ. Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet 1982;2:11-16.
-
(1982)
Lancet
, vol.2
, pp. 11-16
-
-
Filley, W.V.1
Holley, K.E.2
Kephart, G.M.3
Gleich, G.J.4
-
2
-
-
0023875104
-
Purifed interleukin-5 supports the terminal differentiation and proliferation of murine eosinophil precursors
-
Yamaguchi Y, Duda T, Suda J, Eguchi M, Miura Y, Harada N, Tominaga A, Takatsu K. Purifed interleukin-5 supports the terminal differentiation and proliferation of murine eosinophil precursors. J Exp Med 1988; 167:43-56.
-
(1988)
J Exp Med
, vol.167
, pp. 43-56
-
-
Yamaguchi, Y.1
Duda, T.2
Suda, J.3
Eguchi, M.4
Miura, Y.5
Harada, N.6
Tominaga, A.7
Takatsu, K.8
-
3
-
-
0026755576
-
Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects
-
Sehmi R, Wardlaw AJ, Cromwell O, Kurihara K, Waltmann P, Kay AB. Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood 1992;79:2952-2959.
-
(1992)
Blood
, vol.79
, pp. 2952-2959
-
-
Sehmi, R.1
Wardlaw, A.J.2
Cromwell, O.3
Kurihara, K.4
Waltmann, P.5
Kay, A.B.6
-
4
-
-
0024330415
-
IL-5 dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity and sustained antibody-dependent cytotoxicity
-
Rothenberg ME, Petersen J, Stevens RL, Silberstein DS, McKenzie DT, Austen KF, Owen WF. IL-5 dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity and sustained antibody-dependent cytotoxicity. J Immunol 1989;143:2311-2316.
-
(1989)
J Immunol
, vol.143
, pp. 2311-2316
-
-
Rothenberg, M.E.1
Petersen, J.2
Stevens, R.L.3
Silberstein, D.S.4
McKenzie, D.T.5
Austen, K.F.6
Owen, W.F.7
-
5
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie MJ, Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, Mathur AK, Cowley HC, Chung KF, Djukanovic R, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000;356:2114-2116.
-
(2000)
Lancet
, vol.356
, pp. 2114-2116
-
-
Leckie, M.J.1
Brinke, A.2
Khan, J.3
Diamant, Z.4
O'Connor, B.J.5
Walls, C.M.6
Mathur, A.K.7
Cowley, H.C.8
Chung, K.F.9
Djukanovic, R.10
-
6
-
-
0038643527
-
The effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: A pilot study
-
Kips JC, O'Connor BJ, Langley SJ, Woodcock A, Kerstjens HAM, Postma DS, Danzig M, Cuss F, Pauwels RA. The effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am J Respir Crit Care Med 2003;167:1655-1659.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1655-1659
-
-
Kips, J.C.1
O'Connor, B.J.2
Langley, S.J.3
Woodcock, A.4
Kerstjens, H.A.M.5
Postma, D.S.6
Danzig, M.7
Cuss, F.8
Pauwels, R.A.9
-
7
-
-
0037438409
-
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
-
Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 2003;167:199-204.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 199-204
-
-
Flood-Page, P.T.1
Menzies-Gow, A.N.2
Kay, A.B.3
Robinson, D.S.4
-
8
-
-
0036126726
-
The IL-5 receptor on human bronchus selectively primes for hyperresponsiveness
-
Rizzo CA, Yang R, Greenfeder S, Egan RW, Pauwels RA, Hey JA. The IL-5 receptor on human bronchus selectively primes for hyperresponsiveness. J Allergy Clin Immunol 2002;109:404-409.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 404-409
-
-
Rizzo, C.A.1
Yang, R.2
Greenfeder, S.3
Egan, R.W.4
Pauwels, R.A.5
Hey, J.A.6
-
9
-
-
0038360363
-
Anti-IL-5 (mepolizumab) reduces the expression of tenascin, procollagen III and lumican in the reticular basement membrane of human atopic asthmatics
-
Phipps S, Flood-Page P, Menzies-Gow A, Wangoo A, Barnes N, Barkans J, Robinson DS, Kay AB. Anti-IL-5 (mepolizumab) reduces the expression of tenascin, procollagen III and lumican in the reticular basement membrane of human atopic asthmatics. J Allergy Clin Immunol 2003:111:S278.
-
(2003)
J Allergy Clin Immunol
, vol.111
-
-
Phipps, S.1
Flood-Page, P.2
Menzies-Gow, A.3
Wangoo, A.4
Barnes, N.5
Barkans, J.6
Robinson, D.S.7
Kay, A.B.8
-
10
-
-
0036884942
-
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I: Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge
-
Liu LY, Sedgwick JB, Bates ME, Vrtis RF, Gern JE, Kita H, Jarjou NN, Busse WW, Kelly EA. Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I: loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge. J Immunol 2002;169:6452-6458.
-
(2002)
J Immunol
, vol.169
, pp. 6452-6458
-
-
Liu, L.Y.1
Sedgwick, J.B.2
Bates, M.E.3
Vrtis, R.F.4
Gern, J.E.5
Kita, H.6
Jarjou, N.N.7
Busse, W.W.8
Kelly, E.A.9
-
11
-
-
85087538495
-
Differential regulation of human eosinophil IL-3, IL-5 and GM-CSF receptor alpha chain expression by cytokines: IL-3, IL-5 or GM-CSF down regulate IL-5Ra expression with loss of IL-5 responsiveness, but up-regulate IL-3Ra expression
-
In press
-
Gregory B, Kirchem A, Phipps S, Gevaert P, Pridgeon C, Rankin SM, Robinson DS. Differential regulation of human eosinophil IL-3, IL-5 and GM-CSF receptor alpha chain expression by cytokines: IL-3, IL-5 or GM-CSF down regulate IL-5Ra expression with loss of IL-5 responsiveness, but up-regulate IL-3Ra expression. J Immunol (In press).
-
J Immunol
-
-
Gregory, B.1
Kirchem, A.2
Phipps, S.3
Gevaert, P.4
Pridgeon, C.5
Rankin, S.M.6
Robinson, D.S.7
-
12
-
-
0036216507
-
Interleukin-5 and eosinophils as therapeutic targets for asthma
-
Foster PS, Hogan SP, Yang M, Mattes J, Young IG, Matthaei KI, Kumar RK, Mahalingham S, Webb DC. Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends Mol Med 2002;8:162-167.
-
(2002)
Trends Mol Med
, vol.8
, pp. 162-167
-
-
Foster, P.S.1
Hogan, S.P.2
Yang, M.3
Mattes, J.4
Young, I.G.5
Matthaei, K.I.6
Kumar, R.K.7
Mahalingham, S.8
Webb, D.C.9
-
13
-
-
0035105111
-
Elemental signals regulating eosinophil accumulation in the lung
-
Foster PS, Mould AW, Yang M, Mackenzie J, Mattes J, Hogan SP, Mahalingham S, Mckenzie AN, Rothenberg ME, Young IG, et al. Elemental signals regulating eosinophil accumulation in the lung. Immunol Rev 2001;179:173-181.
-
(2001)
Immunol Rev
, vol.179
, pp. 173-181
-
-
Foster, P.S.1
Mould, A.W.2
Yang, M.3
Mackenzie, J.4
Mattes, J.5
Hogan, S.P.6
Mahalingham, S.7
Mckenzie, A.N.8
Rothenberg, M.E.9
Young, I.G.10
|