Limited proteolysis of Escherichia coli cytidine 5′-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis

European Journal of Biochemistry

Volumn 270, Issue 10, 2003, Pages 2195-2206

  Simard, Dave ^a   Hewitt, Kerry A ^a   Lunn, Faylene ^a   Iyengar, Akshai ^a   Bearne, Stephen L ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Activation; Amidotransferase; CTP synthase; Glutaminase; Proteolysis; Site directed mutagenesis

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMIDE; AMMONIA; ARGININE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CYTIDINE TRIPHOSPHATE; GLUTAMINASE; GLUTAMINE; GUANOSINE TRIPHOSPHATE; LYSINE; TRYPSIN; URIDINE TRIPHOSPHATE;

ALLOSTERISM; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONCENTRATION RESPONSE; EFFECTOR CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; RESIDUE ANALYSIS; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SEQUENCE; ARGININE; BINDING SITES; CARBON-NITROGEN LIGASES; CATALYSIS; CIRCULAR DICHROISM; CYTIDINE TRIPHOSPHATE; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ESCHERICHIA COLI; GLUTAMINASE; GLUTAMINE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; KINETICS; LYSINE; MODELS, CHEMICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; TRYPSIN;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0037854730     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03588.x     Document Type: Article

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