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Volumn 148, Issue 2, 2003, Pages

Discovery and mechanism of action of pegvisomant

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; GROWTH HORMONE; HORMONE ANTAGONIST; PEGVISOMANT;

EID: 0037847547     PISSN: 08044635     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (46)

References (24)
  • 1
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    • Okada, S.1    Kopchick, J.J.2
  • 2
  • 5
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    • Growth hormone receptor and serum binding protein: Purification, cloning and expression
    • Leung DW, Spencer SA, Cachianes G, Hammonds RG, Collins C, Henzel WJ et al. Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 1987 330 537-543.
    • (1987) Nature , vol.330 , pp. 537-543
    • Leung, D.W.1    Spencer, S.A.2    Cachianes, G.3    Hammonds, R.G.4    Collins, C.5    Henzel, W.J.6
  • 6
    • 0026346040 scopus 로고
    • Crystals of the complex between human growth hormone and the extracellular domain of its receptor
    • Ultsch M, De Vos AM & Kossiakoff AA. Crystals of the complex between human growth hormone and the extracellular domain of its receptor. Journal of Molecular Biology 1991 222 865-868.
    • (1991) Journal of Molecular Biology , vol.222 , pp. 865-868
    • Ultsch, M.1    De Vos, A.M.2    Kossiakoff, A.A.3
  • 7
    • 0026332810 scopus 로고
    • Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
    • Cunningham BC, Ultsch M, De Vos AM, Mulkerrin MG, Clauser KR & Wells JA. Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 1991 254 821-825.
    • (1991) Science , vol.254 , pp. 821-825
    • Cunningham, B.C.1    Ultsch, M.2    De Vos, A.M.3    Mulkerrin, M.G.4    Clauser, K.R.5    Wells, J.A.6
  • 8
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • De Vos AM, Ultsch M & Kossiakoff AA. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 1992 255 306-312.
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 10
    • 0025322555 scopus 로고
    • Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice
    • Chen WY, Wight DC, Wagner TE & Kopchick JJ. Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice. PNAS 1990 87 5061-5065.
    • (1990) PNAS , vol.87 , pp. 5061-5065
    • Chen, W.Y.1    Wight, D.C.2    Wagner, T.E.3    Kopchick, J.J.4
  • 11
    • 0026048419 scopus 로고
    • Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice
    • Chen WY, White ME, Wagner TE & Kopchick JJ. Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice. Endocrinology 1991 129 1402-1408.
    • (1991) Endocrinology , vol.129 , pp. 1402-1408
    • Chen, W.Y.1    White, M.E.2    Wagner, T.E.3    Kopchick, J.J.4
  • 13
    • 0035040522 scopus 로고    scopus 로고
    • Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer
    • Ross RJ, Leung KC, Maamra M, Bennett W, Doyle N, Waters MJ et al. Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer. Journal of Clinical Endocrinology and Metabolism 2001 86 1716-1723.
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , pp. 1716-1723
    • Ross, R.J.1    Leung, K.C.2    Maamra, M.3    Bennett, W.4    Doyle, N.5    Waters, M.J.6
  • 15
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    • In vitro and in vivo studies of the antagonistic effects of human growth hormone analogs
    • Chen WY, Chen N, Yun J, Wagner TE & Kopchick JJ. In vitro and in vivo studies of the antagonistic effects of human growth hormone analogs. Journal of Biological Chemistry 1994 269 15892-15897.
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    • Chen, W.Y.1    Chen, N.2    Yun, J.3    Wagner, T.E.4    Kopchick, J.J.5
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    • Van Der Lely, A.J.1    Hutson, R.2    Trainer, P.J.3    Besser, G.M.4    Barkan, A.5    Katznelson, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.