Double-blind, randomized, placebo-controlled trial to determine the efficacy of eutectic lidocaine/prilocaine (EMLA) cream for decreasing pain during local anaesthetic infiltration for out-patient haemorrhoidectomy

Asian Journal of Surgery

Volumn 26, Issue 1, 2003, Pages 26-30

  Roxas, M Francisco T ^a   Talip, Babie Normita F ^a   Crisostomo, Armando C ^a  

^a UNIVERSITY OF THE PHILIPPINES MANILA   (Philippines)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; EMLA; LIDOCAINE; LOCAL ANESTHETIC AGENT; PLACEBO; PRILOCAINE;

ADULT; AGED; AMBULATORY SURGERY; ANESTHESIA INDUCTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HEMORRHOID; HEMORRHOIDECTOMY; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTPATIENT; PAIN; PATIENT CARE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; LOCAL ANESTHESIA; PAIN ASSESSMENT; TREATMENT OUTCOME;

ADULT; AMBULATORY SURGICAL PROCEDURES; ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; DOUBLE-BLIND METHOD; FEMALE; HEMORRHOIDS; HUMANS; LIDOCAINE; MALE; PAIN MEASUREMENT; PRILOCAINE; TREATMENT OUTCOME;

EID: 0037842036     PISSN: 10159584     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1015-9584(09)60211-6     Document Type: Article

References (18)

1. Gutierrez R, Recio P, Guerra B, et al. The merit of the use of local anaesthesia in anorectal surgery. Philippine Journal of Surgical Specialties 1970;25:97-101.
2. Barrios G, Recio P. Hemorrhoidectomy in the ambulatory patient. Philippine Journal of Surgical Specialties 1973;28:34-39.
3. Lim F, Navarro N. Out-patient surgical hemorrhoidectomy. Philippine Journal of Surgical Specialties 1989;44:67-71.
4. Lacerda-Filho A, Cunha-Melo J. Outpatient hemorrhoidectomy under local anaesthesia. Eur J Surg 1997;163:935-40.
5. Cataldo TE. Anaesthetic management. In: Beck DE, ed. Handbook of Colorectal Surgery. St. Louis, Missouri, Quality Medical Publishing; 1997:146-60.
6. Nivatvongs S. Local anaesthesia in anorectal surgery. In: Gordon PH, Nivatvongs S, eds. Principles and Practice of Surgery for the Colon, Rectum and Anus. St. Louis, Missouri, Quality Medical Publishing; 1992:139-48.
7. th edition. St. Louis, Missouri, Mosby;1998:267-72.
8. Taddio A, Ohlsson A. Lidocaine-prilocaine cream (EMLA) to reduce pain in male neonates undergoing circumcision (Cochrane Review). In: The Cochrane Library, Issue 3, 1998, Oxford.
9. Vaghadia H, Al Ahdal-OA, Nevin K. EMLA patch for intravenous cannulation in adult surgical patients. Can J Anaesth 1997;44:798-802.
10. Sharma SK, Gajraj NM, Sidawi JE. EMLA cream effectively reduces the pain of spinal needle anaesthesia. Reg Anesth 1996;21:561-4.
11. Himelstein BP, Cnaan A, Blackall CS, et al. Topical application of lidocaine-prilocaine (EMLA) cream reduces the pain of intramuscular infiltration of saline solution. J Pediatr 1996;129:718-21.
12. Elson JA, Paech MJ. EMLA cream prior to insertion of elective epidurals. Anesth Intens Care 1995;23:339-41.
13. Raveh T, Weinberg A, Sibirski O, et al. Efficacy of the topical anaesthetic cream, EMLA, in alleviating both needle insertion and injection pain. Ann Plast Surg 1995;35:576-9.
14. Nott MR, Peacock JL. Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture. Anaesthesia 1990;45:772-4.
15. Ehrenstrom-Reiz G, Reiz S, Stockman O. Topical anaesthesia with EMLA, a new lidocaine-prilocaine cream and the Cusum technique for detection of minimal application time. Acta Anaesthesiol Scand 1983;27:510-2.
16. Ho KS, Eu KW, Heah SM, et al. Randomized clinical trial of haemorrhoidectomy under a mixture of local anaesthesia versus general anaesthesia. Br J Surg 2000;87:410-3.
17. Lal MK, McClelland J, Phillips J, et al. Comparison of EMLA cream versus placebo in children receiving distraction therapy for venipuncture. Acta Paediatr 2001;90:154-9.
18. Tritrakam T, Lertakyamanee J, Koompong P, et al. Both EMLA and placebo cream reduced pain during extracorporeal piezoelectric shock wave lithotripsy with the Piezolith 2300. Anesthesiology 2000;92:1049-54.