Further investigation on meloxicam contraceptivity in female rabbits: Luteinizing unruptured follicles, a microscopic evidence

Contraception

Volumn 67, Issue 6, 2003, Pages 485-489

  Salhab, A S ^a   Amro, B I ^a   Shomaf, M S ^a  

^a UNIVERSITY OF JORDAN   (Jordan)

Author keywords

Anti inflammatory agents; Contraceptivity; Cyclooxygenase 2 inhibitor; Luteinized unruptured follicles; Meloxicam; Ovulation; Suppository

Indexed keywords

ESTROGEN RECEPTOR; MELOXICAM; PROGESTERONE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTRACEPTION; CONTROLLED STUDY; FEMALE; GRANULOSA CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUTEINIZATION; MALE; NONHUMAN; OVARY; OVARY FOLLICLE CELL; OVULATION; PROGESTERONE BLOOD LEVEL; RABBIT; STAINING; WEIGHT GAIN;

EID: 0037838820     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0010-7824(03)00050-7     Document Type: Article

References (18)

1. Richards J.S., Fitzpatric S.L., Clemenes J.W., Morris J.K., Alliston T., Sirois J. Ovarian cell differentiation a cascade of multiple hormones, cellular signals and regulated genes . Recent Prog Hormone Res. 50:1995;323-354.
2. Tsafiri A. Ovulation as a tissue remodeling process. Proteolysis and cumulus expansion. Exp Med Biol. 377:1995;121-140.
3. Vane J.R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature. 231:1971;232-235.
4. Armstrong D.T., Grinwich D.L. Blockade of spontaneous and LH-induced ovulation in rats by indomethacin, an inhibitor of prostaglandin biosynthesis, prostaglandin biosynthesis. Prostaglandins. 1:1972;21-36.
5. Lau I.F., Saksena S.K., Chang M.C. Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis its reversal by prostaglandins and progesterone in mice . Prostaglandins. 4:1972;794-803.
6. Espey L.L., Stein V.I., Dumitrescu J. Survey of anti-inflammatory agents and related drugs as inhibitors of ovulation in the rabbits. Fertil Steril. 38:1982;238-247.
7. Akinlosotu B.A., Verna O.P. Detection of ovulation in goats by blood prostaglandins concentration. Am J Vet Res. 44:1983;1339-1343.
8. Jaszczak S.E. Anovulatory luteal phase in primates. Contraception. 27:1983;505-514.
9. Killick S., Elestein M. Pharmacologic production of luteinised unruptured follicle by prostaglandin synthetase inhibitors. Fertil Steril. 47:1987;733-737.
10. Pall M., Friden B., Brannstrom M. Induction of follicular rupture in the human by the selective COX-2 inhibitor rofecoxib a randomized double-blind study . Hum Reprod. 16:2001;1323-1328.
11. Salhab A.S., Gharaibeh M.N., Shomaf M.S., Amro B.I. Meloxicam inhibits rabbit ovulation. Contraception. 63:2001;329-339.
12. Kaufman R.A., Savoy-Moore R.T., Subramann M.G., Moghissi K.S. Cocaine inhibits mating-induced, but not human chorionic gonadotropin-stimulated ovulation in the rabbit. Biol Reprod. 46:1992;641-647.
13. 2α Fertil Steril. 29:1978;456-458.
14. O'Grady J.P., Caldwell B.V., Auletta F.J., Speroff L. The effects of an inhibitor of prostaglandin synthesis (indomethacin) on ovulation, pregnancy and pseudopregnancy in the rabbit. Prostaglandins. 1:1972;97-106.
15. Grinwich D.L., Kennedy T.G., Armstrong D.T. Dissociation of ovulatory and steroidogenic action of luteinising hormone in rabbits with indomethacin, an inhibitor of prostaglandin biosynthesis. Prostaglandins. 1:1972;89-96.
16. Smith G., Roberts R., Hall C., Nuki G. Reversible ovulatory failure associated with the development of luteinized unruptured follicles in women with inflammatory arthritis taking non-steroidal anti-inflammatory drugs. Br J Rheumatol. 35:1996;458-462.
17. Akil M., Amos R., Stewart P. Infertility may sometimes be associated with NSAID consumption. Br J Rheumatol. 35:1996;76-78.
18. Manuel D. Meloxicam clinical data on a preferential cyclooxygenase-2 inhibitor. J Clin Rheumatol. 4:1998;S32-S34.