Autism and mental retardation: The genetic relationship and contribution

Eastern Mediterranean Health Journal

Volumn 7, Issue 3, 2001, Pages 536-543

  El Hazmi, M A F ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; CHROMOSOME 13; CHROMOSOME 15; CHROMOSOME 7; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MENTAL DEFICIENCY; PEDIGREE; POPULATION GENETICS; REVIEW; RISK FACTOR; TWINS;

AUTISTIC DISORDER; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; HUMANS; LINKAGE (GENETICS); MALE; MENTAL RETARDATION; PEDIGREE; RISK FACTORS; TWIN STUDIES;

EID: 0037837515     PISSN: 10203397     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (47)

1. Lelord G et al. L'autisme de l'enfant: une déficience relationnelle liée a un trouble du développement du système nerveux central. [Childhood autism: a relating deficiency due to a developmental disorder of the central nervous system.] Bulletin de l'Académie Nationale de Médecine, 1993, 177(8):1423-30.
2. Minshew NJ, Sweeney JA, Bauman ML Neurological aspects of autism. In: Cohen DJ, Volkmar FR, eds. Handbook of autism and pervasive developmental disorders, 2nd ed. New York, John Wiley and Sons, 1997:344-69.
3. Rapin I. Autism. New England journal of medicine, 1997, 337:97-104.
4. Goldstein G, Minshen NJ, Siegel DJ. Age differences in academic achievement in high-functioning autistic individuals. Journal of clinical and experimental neuropsychology, 1994, 16(5):671-80.
5. Minshen NJ, Payton JB. New prospectus in autism. Part I: the clinical spectrum of infantile autism. Current problems in pediatrics, 1988, 18:561-610.
6. Klin A. Auditory brain stem responses in autism: brain stem dysfunction or peripheral hearing loss? Journal of autism and developmental disorders, 1993, 23:15-35.
7. Klein SK et al. Electrophysiologic manifestations of impaired temporal lobe auditory processing in verbal auditory agnosia. Brain and language, 1995, 51:383-405.
8. Tuchman RF, Rapin I, Shinnar S. Autistic and dysphasic children. I. Clinical characteristics. Pediatrics, 1991, 88:1211-8.
9. Rapin I, Dunn M. Language disorders in children with autism. Seminars in pediatric neurology, 1997, 4:86-92.
10. Wainwright L, Fein D. Play. In: Rapin I, ed. Preschool children with inadequate communication: developmental language disorder, autism, low IQ. London, MacKeith Press, 1996:173-89.
11. Tuchman RF, Rapin I. Regression in pervasive developmental disorders: seizures and epileptiform EEG correlates. Pediatrics, 1997, 99:560-6.
12. Nelson KB. Prenatal and perinatal factors in the etiology of autism. Pediatrics, 1991, 87:761-6.
13. Cohen IL et al. Why are autism and fragile-X syndrome associated? Conceptual and methodological issues. American journal of human genetics, 1991, 48:195-202.
14. Plomin R, Own MJ, McGuffin P. The genetic basis of complex human behaviors. Science, 1994, 264:1733-9.
15. Bishop DVM. Autism, Asperger's syndrome and semantic-pragmatic disorder: where are the boundaries? British journal of disorders of communication, 1989, 24:107-21.
16. Thomsen P. Obsessive-compulsive disorder in children and adolescents: a review of the literature. European child and adolescent psychiatry, 1994, 3:138-58.
17. DeLong GR. Children with autistic spectrum disorder and a family history of affective disorder. Developmental medicine and child neurology, 1994, 36:674-88.
18. Summers JA et al. Behaviour problems in Angelman syndrome. Journal of intellectual disability research, 1995, 39:97-106.
19. Smalley SL et al. Autism and tuberous sclerosis. Journal of autism and developmental disorders, 1992, 22:339-55.
20. Chess S, Korn SJ, Fernandez PB. Psychiatric disorders of children with congenital rubella. New York, Brunner/ Mazel, 1971.
21. Gillberg C, Coleman M. The biology of the autistic syndromes, 2nd ed. London, MacKeith Press, 1992.
22. Fernell E, Gillberg C, von Wendt L. Autistic symptoms in children with infantile hydrocephalus. Acta paediatrica scandinavica, 1991, 80:451-7.
23. Klin A et al. Validity and neuropsychological characterization of Asperger syndrome: convergence with nonverbal learning disabilities syndrome. Journal of child psychology and psychiatry, 1995, 36:1127-40.
24. Frith U. Autism. Scientific American, 1993, 268:108-14.
25. Tierney E et al. Behavior phenotype in the RSH/Smith-Lenli-Optiz syndrome. American journal of medicine and genetics, 2001, 93(2):191-200.
26. Ozonoff S et al. Behavior phenotype of FG syndrome: cognition, personality and behavior: eleven affected boys. American journal of medicine and genetics, 2000, 97(2):112-8.
27. Persico AM et al. Adenosine deaminase alleles and autistic disorder: case - control and family-based association studies. American journal of medicine and genetics, 2000, 96(6):784-90.
28. McIntosh H. Autism is likely to be linked to several genes. American Psychological Association monitor, 1998, 29(11):1-4.
29. Gillberg C et al. Autism associated with marker chromosome. Journal of the American Academy of Child and Adolescent Psychiatry, 1991, 30(3):489-94.
30. Baker P et al. Brief report: duplication of chromosome 15q11-13 in two individuals with autistic disorder. Journal of autism and developmental disorders, 1994, 24:529-35.
31. McIntosh H. Autism is likely to be linked to several genes. American Psychological Association, 1998, 28:1-3.
32. Schroer RJ et al. Autism and maternally derived aberrations of chromosome 15q. American journal of medicine and genetics, 1998, 76(4):327-36.
33. Martinsson T et al. Maternal origin of inv dup(15) chromosomes in infantile autism. European child and adolescent psychiatry, 1996, 5(4):185-92.
34. Coom Jr EH et al. Autism or atypical autism in maternally but not paternally derived proximal 15q duplication. American journal of human genetics, 1997, 60(4):928-34.
35. Schroer RJ et al. Autism and maternally derived aberrations of chromosome 15q. American Journal of medicine and genetics, 1998, 76(4):327-36.
36. Fleijter WL et al. Cytogenetic and molecular analysis of inv dup (15) chromosomes observed in two patients with autistic disorder and mental retardation. American journal of medicine and genetics, 1996, 61(2):182-7.
37. International Molecular Genetic Study of Autism Consortium. A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Human molecular genetics, 1998, 7(3):571-8.
38. Ritvo E. First reported chromosome 13 and recessive form of autism. FEATNEWS-EAST digest, 1999.
39. Vincent JB et al. Identification of a novel gene on chromosome 7q31 that is interrupted by a translocation breakpoint in an autistic individual. American journal of human genetics, 2000, 67:510-4.
40. Park JP et al. Smith-Magenis syndrome resulting from a de novo direct insertion of proximal 17q into 17p11.2. American journal of medicine and genetics, 1998, 77(1):23-7.
41. Jayakar P et al. Fra(2)(q13) and inv(9)(p11q12) in autism: causal relationship? American journal of medical genetics, 1986, 23(1-2):381-92.
42. Monaghan KG et al. Cytogenetic and clinical findings in a patient with a deletion of 16q23.1: first report of bilateral cataracts and a 16q deletion. American Journal of medical genetics, 1997, 73(2):180-3.
43. Ishikawa-Brush Y et al. Autism and multiple exostoses associated with an X;8 translocation occurring within the GHPR gene and 3′ to the SDC2 gene. Human molecular genetics, 1997, 6(8):1241-50.
44. Shaffer LG et al. A clinical and molecular study of mosaicism for trisomy 17. Human genetics, 1996, 97(1):69-72.
45. Scourfield J, McGuffin P, Thapar A. Genes and social skills. BioEssays, 1997, 19(12):1125-7.
46. Fischer KM. Genes for Prader-Willi syndrome/Angelman syndrome and fragile X syndrome are homologous, with genetic imprinting and unstable trinucleotide repeats causing mental retardation, autism and aggression. Medical hypotheses, 1996, 47(4):289-98.
47. Herault J et al. Possible association of c-Harvey-ras-1 (HRAS-1) marker with autism. Psychiatry research, 1993, 46(3): 261-7.