Emotions are building up in the field of extracellular proteolysis

Trends in Molecular Medicine

Volumn 9, Issue 5, 2003, Pages 183-185

  Madani, Rime ^a   Nef, Serge ^b   Vassalli, Jean Dominique ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMIN; TISSUE PLASMINOGEN ACTIVATOR;

CENTRAL NERVOUS SYSTEM; EMOTION; HUMAN; LEARNING; MEMORY; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; PROTEIN DEGRADATION; REVIEW;

EID: 0037833494     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(03)00050-9     Document Type: Review

References (21)

1. Sappino, A.P. et al. (1993) Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92, 679-685
2. Madani, R. et al. (1999) Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice. EMBO J. 18, 3007-3012
3. Pawlak, R. et al. (2003) Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior. Nat. Neurosci. 6, 168-174
4. Qian, Z. et al. (1993) Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457
5. Huarte, J. et al. (1987) Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA. Genes Dev. 1, 1201-1211
6. Salles, F.J. and Strickland, S. (2002) Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus. J. Neurosci. 22, 2125-2134
7. Strickland, S. (2001) Tissue plasminogen activator in nervous system function and dysfunction. Thromb. Haemost. 86, 138-143
8. Gualandris, A. et al. (1996) Membrane depolarization induces calciumdependent secretion of tissue plasminogen activator. J. Neurosci. 16, 2220-2225
9. Mansuy, I.M. et al. (1993) Variable and multiple expression of protease nexin-1 during mouse organogenesis and nervous system development. Development 119, 1119-1134
10. Krueger, S.R. et al. (1997) Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse. J. Neurosci. 17, 8984-8996
11. Zhuo, M. et al. (2000) Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation. J. Neurosci. 20, 542-549
12. Nicole, O. et al. (2001) The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nat. Med. 7, 59-64
13. Steward, O. and Schuman, E.M. (2001) Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. 24, 299-325
14. Huang, Y. et al. (1996) Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. U. S. A. 93, 8699-8704
15. Gabriel, C. et al. (2003) Transforming growth factor α-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity. FASEB J. 17, 277-279
16. Madani, R. et al. Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin. Mol. Cell. Neurosci. (in press)
17. Pawlak, R. et al. (2002) Tissue plasminogen activator and seizures: a clot-buster's secret life. J. Clin. Invest. 109, 1529-1531
18. Cinelli, P. et al. (2001) Neuroserpin, a neuroprotective factor in focal ischemic stroke. Mol. Cell. Neurosci. 18, 443-457
19. Tucker, H.M. et al. (2000) The plasmin system is induced by and degrades amyloid-β aggregates. J. Neurosci. 20, 3937-3946
20. Molinari, F. et al. (2002) Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation. Science 298, 1779-1781
21. Davis, R.L. et al. (1999) Familial encephalopathy with neuroserpin inclusion bodies. Am. J. Pathol. 155, 1901-1913