Improvement of regional cerebral blood flow after treatment with branched-chain amino acid solutions in patients with cirrhosis

European Journal of Gastroenterology and Hepatology

Volumn 15, Issue 7, 2003, Pages 733-737

  Iwasa, Motoh ^a   Matsumura, Kaname ^a   Watanabe, Yuri ^a   Yamamoto, Mika ^a   Kaito, Masahiko ^a   Ikoma, Jiro ^a   Gabazza, Esteban C ^a   Takeda, Kan ^a   Adachi, Yukihiko ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Branched chain amino acids; Cerebral blood flow; Liver cirrhosis; Single photon emission computed tomography

Indexed keywords

BRANCHED CHAIN AMINO ACID;

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; BRAIN MAPPING; BRAIN PERFUSION; CEREBELLUM; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FRONTAL LOBE; HUMAN; LIVER CIRRHOSIS; MALE; OCCIPITAL LOBE; PARIETAL LOBE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL LOBE;

EID: 0037825911     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.meg.0000059162.46867.f0     Document Type: Article

References (18)

1. Iwasa M, Matsumura K, Kaito M, Ikoma J, Kobayashi Y, Nakagawa N, et al. Decrease of regional cerebral blood flow in liver cirrhosis. Eur J Gastroenterol Hepatol 2000; 12:1001-1006.
2. Rodriguez G, Testa R, Celle G, Gris A, Marenco S, Nobili F, et al. Reduction of cerebral blood flow in subclinical hepatic encephalopathy and its correlation with plasma-free tryptophan. J Cereb Blood Flow Metab 1987; 7:768-772.
3. 99mTc-HMPAO single-photon emission computed tomography: effect of liver transplantation. J Hepatol 1998; 29:78-84.
4. Guevara M, Bru C, Gines P, Fernadez-Esparrach G, Sort P, Bataller R, et al. Increased cerebrovascular resistance in cirrhotic patients with ascites. Hepatology 1998; 28:39-44.
5. Kawamura-Yasui N, Kaito M, Nakagawa N, Fujita N, Ikoma J, Gabazza EC, et al. Evaluating response to nutritional therapy using the branched-chain amino acid/tyrosine ratio in patients with chronic liver disease. J Clin Lab Anal 1999; 13:31-34.
6. Chang LT. A method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci Soc 1979; 25:638-643.
7. Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab 1991; 11:690-699.
8. Friston KJ, Holmes AP, Worsley KJ. Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 1995; 26:265-277.
9. Naylor CD, O'Rourke K, Detsky AS, Baker JP. Parenteral nutrition with branched-chain amino acids in hepatic encephalopathy. Gastroenterology 1989; 97:1033-1042.
10. Rossi Fanelli F, Cangiano C, Capocaccia L, Cascino A, Ceci F, Muscaritoli M, et al. Use of branched chain amino acids for treating hepatic encephalopathy: clinical experiences. Gut 1986; 27:111-115.
11. Fraser CL, Arieff AI. Hepatic encephalopathy. N Engl J Med 1985; 313:865-873.
12. Ichida T, Shibasaki K, Muto Y, Muto Y, Satoh S, Watanabe A, et al. Clinical study of an enteral branched-chain amino acid solution in decompensated liver cirrhosis with hepatic encephalopathy. Nutrition 1995; 11:238-244.
13. Plauth M, Egberts EH, Hamster W, Torok M, Muller PH, Brand O, et al. Long-term treatment of latent portosystemic encephalopathy with branched-chain amino acids. A double-blind placebo-controlled crossover study. J Hepatol 1993; 17:308-314.
14. Egberts EH, Schomerus H, Hamster W, Jurgens P. Branched-chain amino acids in the treatment of latent portosystemic encephalopathy. A double-blind placebo-controlled crossover study. Gastroenterology 1985; 88:887-895.
15. Wright PD, Holdsworth JD, Dionigi P, Clague MB, James OF. Effect of branched chain amino acid infusions on body protein metabolism in cirrhosis of liver. Gut 1986; 27:96-102.
16. Reutens DC, McHugh MD, Toussaint PJ, Evans AC, Gjedde A, Meyer E, et al. L-Arginine infusion increases basal but not activated cerebral blood flow in humans. J Cereb Blood Flow Metab 1997; 17:309-315.
17. Pardo JV, Fox PT, Raichle ME. Localization of a human system for sustained attention by positron emission tomography. Nature 1991; 349:61-64.
18. Corbetta M, Shulman GL, Miezin FM, Petersen SE. Superior parietal codex activation during spatial attention shifts and visual feature conjunction. Science 1995; 270:802-805.