Potential inhibitors of angiogenesis. Part I: 3-(Imidazol-4(5)-ylmethylene)indolin-2-ones

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 3, 2003, Pages 243-252

  Braud, Emmanuelle ^a   Duflos, Muriel ^a   Nourrisson, Marie Renee ^a   Tonnerre, Alain ^a   Picot, Carine ^a   Le Baut, Guillaume ^a   Renard, Pierre ^b   Pfeiffer, Bruno ^b   Tucker, Gordon ^c  

^a UNIVERSITÉ DE NANTES   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

3 (imidazol 4(5) ylmethylene)indolin 2 one; Angiogenesis; Cancer; Epidermal growth factor (EGF); Indolin 2 one; Vascular density index (VDI)

Indexed keywords

1 METHOXY 3 (1 IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 2,4 DIMETHYL 5 (2 OXO 1H INDOL 3 YLMETHYLENE) 3 PYRROLEPROPIONIC ACID; 3 (1 METHYLIMIDAZOL 4 YLMETHYLENE) 4 TRIFLUOROMETHYLINDOLIN 2 ONE; 3 (1 METHYLIMIDAZOL 4 YLMETHYLENE) 6 TRIFLUOROMETHYLINDOLIN 2 ONE; 3 (1 METHYLIMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 3 (IMIDAZOL 4 YLMETHYLENE) 6 PHENYLINDOLIN 2 ONE; 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 4 ACETYLAMINO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 4 AMINO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 4 BROMO 3 (1 IMIDAZOL 4 YLMETHYLENE) 1 METHOXYINDOLIN 2 ONE; 4 BROMO 3 (1 METHYLIMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 4 BROMO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 5 BROMO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 5 CHLORO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 6 BROMO 3 (1 METHYLIMIDAZOL 5 YLMETHYLENE)INDOLIN 2 ONE; 6 BROMO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 6 CHLORO 3 (1 METHYLIMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; 6 CHLORO 3 (IMIDAZOL 4 YLMETHYLENE)INDOLIN 2 ONE; ANGIOGENESIS INHIBITOR; CILENGITIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; FUMAGILLOL CHLOROACETYLCARBAMATE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; KETONE DERIVATIVE; PROTEIN TYROSINE KINASE INHIBITOR; PYRROLE DERIVATIVE; SEMAXANIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VATALANIB;

ANGIOGENESIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; KNOEVENAGEL CONDENSATION; MANNICH REACTION; METHYLATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANGIOGENESIS INHIBITORS; ANIMALS; AORTA; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; INDOLES; MALE; METHYLATION; MODELS, CHEMICAL; NITROGEN; PROTEIN-TYROSINE KINASES; PYRROLES; RATS; RATS, INBRED F344; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 0037820400     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636031000106575     Document Type: Article

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