Trapping and extraction of target DNA molecules using periodically crossed electrophoresis in the micropillar array

Proceedings of the IEEE Micro Electro Mechanical Systems (MEMS)

Volumn , Issue , 2003, Pages 231-234

  Yi, Soyeon ^a   Seo, Kyoung Sun ^a   Cho, Young Ho ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRIC FIELDS; ELECTROPHORESIS; EXTRACTION; MICROMACHINING; MOLECULES;

DNA MICROEXTRACTORS; MICROPILLAR ARRAY;

DNA;

EID: 0037818317     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (9)

1. M.W. McDonell, M.N. Simon and F.W. Studier, "Analysis of Restriction Fragments of T7 DNA and Determination of Molecular Weights by Electrophoresis in Neutral and Alkaline Gels," J. Mol. Biol., Vol.110 (1977) pp.119-146.
2. D. Ertas, "Lateral Separation of Macromolecules and Polyelectrolytes in Microlithographic Arrays," Phys. Rev. Lett., Vol.80 (1998) pp.1548-1551.
3. W.D. Volkmuth and R.H. Austin, "DNA Electrophoresis in Microlithographic Arrays," Nature, Vol.358 (1992) pp. 600-602.
4. T.A.J. Duke, R.H. Austin, E.C. Cox and S.S. Chan, "Pulsed-field Electrophoresis in Microlithographic Arrays," Electrophoresis, Vol.17 (1996) pp.1075-1079.
5. O. Bakajin, T.A.J. Duke, J. Tegenfeldt, C. Chou, S.S. Chan, R.H. Austin and E.C. Cox, "Separation of 100-Kilobase DNA Molecules in 10 Seconds," Anal. Chem., Vol.73 (2000) pp. 6053-6056.
6. J. Han and H.G. Craighead, "Separation of Long DNA Molecules in a Microfabricated Entropic Trap Array," Science, Vol.288 (2000), pp.1026-1029.
7. B. Akerman and M. Jonsson, "Reorientational Dynamics and Mobility of DNA during Pulsed-Field Agarose Gel Electrophoresis," J. Phys. Chem., Vol.94 (1990) pp.3828-3838
8. J.L. Viovy, "Reptation-breathing Theory of Pulsed Electrophoresis: Dynamic Regimes, Antiresonance and Symmetry Breakdown Effects," Electrophoresis, Vol.10 (1989) pp.429-441.
9. H.P. Chou, C. Spence, A. Scherer and S. Quake, "A Microfabricated Device for Sizing and Sorting DNA Molecules," Proc. Natl. Acad. Sci., Vol.96 (1999) pp.11-13