Patatin, the tuber storage protein of potato (Solanum tuberosum L.), exhibits antioxidant activity in vitro

Journal of Agricultural and Food Chemistry

Volumn 51, Issue 15, 2003, Pages 4389-4393

  Liu, Yen Wenn ^a   Han, Chuan Hsiao ^a   Lee, Mei Hsien ^a   Hsu, Feng Lin ^a   Hou, Wen Chi ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

1,1 diphenyl 2 picrylhydrazyl (DPPH); Antioxidant; Electron paramagnetic resonance (EPR); Hydroxyl radical; Solanum tuberosum; Storage protein

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; DIHYDRORHODAMINE 123; IODOACETAMIDE; LOW DENSITY LIPOPROTEIN; N BROMOSUCCINIMIDE; PATATIN; PEROXYNITRITE; PROTEIN; RADICAL; RHODAMINE 123; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ASSAY; DNA DAMAGE; ELECTRON SPIN RESONANCE; FOOD COMPOSITION; IC 50; IN VITRO STUDY; LIPID PEROXIDATION; MOLECULAR WEIGHT; POTATO; PROTEIN CONTENT; PROTEIN PURIFICATION;

ANIMALS; ANTIOXIDANTS; CARBOXYLIC ESTER HYDROLASES; CATTLE; COPPER; DNA DAMAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; HUMANS; HYDROXYL RADICAL; LIPID PEROXIDATION; LIPOPROTEINS, LDL; PICRATES; PLANT PROTEINS; SOLANUM TUBEROSUM; THYMUS GLAND;

SOLANUM; SOLANUM TUBEROSUM;

EID: 0037816591     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf030016j     Document Type: Article

References (24)

1. Harman, D. Role of antioxidant nutrients in aging: overview. Age 1995, 18, 51-62.
2. Ames, B. N. Dietary carcinogens and anticarcinogens: oxygen radicals and degenerative diseases. Science 1983, 221, 1256-1264.
3. Gey, K. F. The antioxidant hypothesis of cardiovascular disease: epidemiology and mechanisms. Biochem. Soc. Trans. 1990, 18, 1041-1045.
4. Yen, G. C.; Chuang, D. Y. Antioxidant properties of water extracts from Cassia tora L. in relation to the degree of roasting. J. Agric. Food Chem. 2000, 48, 2760-2765.
5. Rice-Evans, C. A.; Miller, N. J.: Paganga, G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997, 2, 152-159.
6. Hou, W. C.; Chen, Y. C.; Chen, H. J.; Lin, Y. H.; Yang, L. L.; Lee, M. H. Antioxidant activities of trypsin inhibitor, a 33 kDa root storage protein of sweetpotato (Ipomoea batatas (L.) Lam cv. Tainong 57). J. Agric. Food Chem. 2001, 49, 2978-2981.
7. Hou, W. C.; Lee, M. H.; Chen, H. J.; Liang, W. L.; Han, C. H.; Liu, Y. W.; Lin, Y. H. Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber. J. Agric. Food Chem. 2001, 49, 4956-4960.
8. Allen, J. C.; Wrieden, W. L. Influence of milk proteins on lipid oxidation in aqueous emulsion I. Casein, whey protein and α-lactalbumin. J. Dairy Res. 1982, 49, 239-248.
9. Allen, J. C.; Wrieden, W. L. Influence of milk proteins on lipid oxidation in aqueous emulsion II. Lactoperoxidase, lactoferrin, superoxide dismutase and xanthine oxidase. J. Dairy Res. 1982, 49, 249-263.
10. Andrews, D. L.; Beames, B.; Summers, M. D.; Park, W. D. Characterization of the lipid acyl hydrolase activity of the major potato (Solanum tuberosum) tuber protain, patatin, by cloning and abundant expression in a baculovirus vector. Biochem. J. 1988, 252, 199-206.
11. Al-Saikhan, M. S.; Howard, L. R.; Miller, J. C., Jr. Antioxidant activity and total phenolics in different genotypes of potato (Solanum tuberosum, L.) J. Food Sci. 1995, 60, 341-343, 347.
12. Racusen, D.; Foote, M. A major soluble glycoprotein of potato tubers. J. Food Biochem. 1980, 4, 43-52.
13. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
14. Neuhoff, V.; Stamm, R.; Eibl, H. Clear background and highly sensitive protein staining with Coomassie blue dyes in polyacrylamide gels: a systematic analysis. Electrophoresis 1985, 6, 427-448.
15. Hou, W. C.; Hsu, F. L.; Lee, M. H. Yam (Dioscorea batatas Decne) tuber mucilage exhibited antioxidant activities in vitro. Planta Med. 2002, 68, 1072-1076.
16. Kohno, M.; Yamada, M.; Mitsuta, K.; Mizuta, Y.; Yoshikawa, T. Spin-trapping studies on the reaction of iron complexes with peroxides and the effects of water-soluble antioxidants. Bull. Chem. Soc. Jpn. 1991, 64, 1447-1453.
17. Wen, L.; Miao, Z. W.; Qing, W. D. Chemical modification of xylanase from Trichosporon cutaneum shows the presence of carboxyl groups and cysteine residues essential for enzyme activity. J. Protein Chem. 1999, 18, 677-686.
18. Uhteg, L. C.; Lundblad, R. L. The modification of tryptophan in bovine thrombin. Biochim. Biophys. Acta 1977, 491, 551-557.
19. Yan, L. J.; Droy-Lefaix, T.; Packer, L. Ginkgo biloba extract (Egb 761) protects human low-density lipoproteins against oxidative modification mediated by copper. Biochem. Biophys. Res. Commun. 1995, 212, 360-366.
20. Kooy, N. W.; Royall, J. A.; Ischiropoulos, H.; Beckman, J. S. Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radical Biol. Med. 1994, 16, 149-156.
21. Yan, X.; Suzuki, M.; Ohnish-Kameyama, M.; Sada, Y.; Nakanishi, T.; Nagata, T. Extraction and identification of antioxidants in roots of yacon (Smallanthus sonchifolius). J. Agric. Food Chem. 1999, 47, 4711-4713.
22. Steinbrecher, U. P. Oxidation of human low-density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J. Biol. Chem. 1987, 262, 3603-3608.
23. Halliwell, B. Food-derived antioxidants. Evaluation their importance in food and in vivo. Food Sci. Agric. Chem. 1999, 1, 67-109.
24. Brannan, R. G.; Connolly, B. J.; Decker, E. A. Peroxynitrite: a potential initiator of lipid oxidation in food. Trends Food Sci. Technol. 2001, 12, 164-173.