A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria

Southeast Asian Journal of Tropical Medicine and Public Health

Volumn 33, Issue 3, 2002, Pages 525-531

  Krudsood, S ^a   Buchachart, K ^a   Chalermrut, K ^b   Charusabha, C ^a   Treeprasertsuk, S ^a   Haoharn, O ^b   Duangdee, C ^b   Looareesuwan, S ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; AZITHROMYCIN; DIHYDROQUINGHAOSU; MEFLOQUINE; SESQUITERPENE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COMBINATION; FEMALE; HUMAN; MALARIA FALCIPARUM; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE; NONPARAMETRIC TEST; THAILAND;

ADOLESCENT; ADULT; AGED; ANTIMALARIALS; ARTEMISININS; AZITHROMYCIN; DRUG COMBINATIONS; DRUG RESISTANCE, MULTIPLE; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; MEFLOQUINE; MIDDLE AGED; SESQUITERPENES; STATISTICS, NONPARAMETRIC; THAILAND;

EID: 0037812498     PISSN: 01251562     EISSN: 26975718     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Andersen SL, Ager AL, McGreevy P, et al. Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. Am J Trop Med Hyg 1994a; 52: 159-60.
2. Andersen SL, Ager AL. McGreevy P, Schuster BG, Ellis W, Berman J. Efficacy of azithromycin as a casual prophylactic agent against murine malaria. Antimicrob Agents Chemother 1994b; 38: 1862-3.
3. Andersen SL, Berman J, Kuschner R, et al. Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. Ann Intern Med 1995; 123: 771-3.
4. Biswas S. In-vitro antimalarial activity of azithromycin against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. J Postgrad Med 2001; 47: 240-3.
5. De Mol P, Alimenti A, Franchart G, Waelbroeck A, Lery J. Azithromycin versus erythromycin in the treatment of lower respiratory tract infections in children. ICMAS 1996: 76-7.
6. Gingras BA, Jansen JB. Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. Am J Trop Med Hyg 1993; 49: 101-5.
7. Harinasuta T, Bunnag D, Vanijanonta S, et al. Mefloquine, sulfadoxine and pyrimethamine in the treatment of symptomatic falciparum malaria: a double-blind trial for determining the most effective dose. Bull WHO 1987; 63: 363-7.
8. Kain KC, Shanks GD, Keystone JS. Malaria chemoprophylaxis in the age of drug resistant. I. Currently recommended drug regimens. Clin Infect Dis 2001; 33: 226-34.
9. Klayman DL. Qinghaosu (artemisinin): an antimalarial drug from China. Science 1985; 228: 1049-55.
10. Krudsood S, Silachamroon U, Wilairatana P, et al. A randomized clinical trial of combinations of artesunate and azithromycin for treatment of uncomplicated Plasmodium falciparum malaria in Thailand. Southeast Asian J Trop Med Public Health 2000; 31: 801-7.
11. Kushner RA, Heppner DG, Andersen SL, et al. Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. Lancet 1994; 343: 1396-7.
12. Looareesuwan S, Harinasuta T, Chongsuphajaisiddhi T. Drug resistant malaria with special reference to Thailand. Southeast Asian J Trop Med Public Health 1992a; 23: 621-34.
13. Looareesuwan S, Wilairatana P, Vanijanonta S, et al. Efficacy of quinine-tetracycline for acute uncom-plicated falciparum malaria in Thailand. Lancet 1992b; 339: 69.
14. Looareesuwan S, Kyle DE, Viravan C, et al. Treatment of patients with recrudescent falciparum malaria with a sequential combination of artesunate and mefloquine. Am J Trop Med Hyg 1992c; 74: 794-9.
15. Looareesuwan S, Vanijanonta S, Viravan C, et al. Randomized trial of mefloquine-tetracycline and quinine-tetracycline for acute uncomplicated falciparum malaria. Acta Trop 1994a; 57: 47-53.
16. Looareesuwan S, Vanijanonta S, Viravan C, Wilairatana P, Charoenlarp P, Andrial M. Randomized trial of mefloquine alone, and artesunate followed by mefloquine for the treatment of acute uncomplicated falciparum malaria. Ann Trop Med Parasitol 1994b; 88: 131-6.
17. Looareesuwan S. Viravan C, Vanijanonta S, Wilairatana P, Pittisuthithum P, Andrial M. Comparative clinical trial of artesunate followed by mefloquine in the treatment of uncomplicated falciparum malaria: two and three-day regimens. Am J Trop Med Hyg 1996a; 54: 210-3.
18. Looareesuwan S, Wilairatana P, Vanijanonta S, et al. Treatment of acute uncomplicated falciparum malaria with oral dihydroartemisinin. Ann Trop Med Parasitol 1996b; 90: 21-8.
19. Luxemburger C, Nosten F, White NJ, et al. Oral artesunate in the treatment of uncomplicated hyperparastemic falciparum malaria. Am J Trop Med Hyg 1995; 53: 522-25.
20. Na-Bangchang K, Kanda T, Tipawangso P, et al. Activity of artemether-azithromycin versus artemether-doxycycline in the treatment of multiple drug resistant falciparum malaria. Southeast Asian J Trop Med Public Heath 1996; 27: 522-5.
21. Noedl H, Wernsdorfer WH, Krudsood S. et al. Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. Acta Trop 2001; 80: 39-44.
22. Nosten F, Imvithaya S, Vincenti M, et al. Malaria on the Thai-Burmese border: treatment of 5,192 patients with mefloquine-sulfadoxine-pyrimethamine. Bull WHO 1987; 65: 891-6.
23. Nosten F, Luxemburger C, ter Kuile F, et al. Optimum artesunate-mefloquine combination for the treatment of multidrug resistant Plasmodium falciparum malaria. J Infect Dis 1994; 170: 971-7.
24. Nosten F, ter Kuile F, Chongsuphajaisiddhi T, et al. Mefloquine-resistant falciparum malaria on the Thai-Burmese border. Lancet 1991; i: 1140-3.
25. Peters DH, Friedel A, McTavish D. Azithromycin: a review of its antimicrobial activity, pharmocokinetic properties and clinical efficacy. Drugs 1992; 44: 750-9.
26. Prince RN, Nosten F, Luxemburger C, et al. Artesunate versus artemether in combination with mefloquine for the treatment of multidrug resistant falciparum malaria. Trans R Soc Trop Med Hyg 1995; 89: 523-7.
27. Prince RN, Nosten F, Luxenburger C, et al. Artesunate-mefloquine treatment of 1967 pateints with multidrug resistant falciparum malaria. Trans R Soc Trop Hyg 1997; 91: 574-7.
28. Taylor WR, Richie TL, Fryauff DJ, et al. Malaria prophylaxis using azithromycin: a double blind, placebo-controlled trial in Irian Jaya, Indonesia. Clin Infect Dis 1999; 28: 74-81.
29. th ed. USA: McGraw-Hill. 1998: 1180-9.
30. Wilairatana P, Chantavanich P, Singhasivanon P, et al. A comparison of three different dihydroartemisinin formulations for the treatment of acute uncomplicated falciparum malaria in Thailand. Int J Parasitol 1998; 28: 1213-18.
31. nd ed. Geneva: WHO, 2000.