Identification and cloning of jipA encoding a polypeptide that interacts with a homolog of yeast Rad6, UVSJ in Aspergillus nidulans

Journal of Microbiology

Volumn 41, Issue 1, 2003, Pages 46-51

  Cho, Jae Han ^a   Yun, Seok Soong ^a   Jang, Young Kug ^a,b   Cha, Mee Jeong ^a   Kwon, Nak Jung ^a   Chae, Suhn Kee ^a  

^a PaiChai University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Aspergillus nidulans; DNA repair; RAD6; TIP41; TOR pathway; UvsJ

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; FUNGAL PROTEIN; MUTANT PROTEIN; POLYPEPTIDE; PROTEIN RAD18; PROTEIN RAD6; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ASPERGILLUS NIDULANS; CARBOXY TERMINAL SEQUENCE; CHROMOSOME; DNA LIBRARY; DNA STRAND BREAKAGE; FUNGAL GENETICS; FUNGUS IDENTIFICATION; GENE LIBRARY; GENE SEQUENCE; GENETIC CODE; GENETIC TRANSCRIPTION; GENOME; IN VITRO STUDY; INTRON; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; TWO HYBRID SYSTEM; YEAST;

ASPERGILLUS; EMERICELLA NIDULANS; EUKARYOTA; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0037804656     PISSN: 12258873     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Abraham, R. 2002. Identification of TOR signaling complexes. more TORC for the cell growth engine. Cell 4, 9-12.
2. Bailly, V., J. Bailly, P. Lamb, S.P. Sung, and L. Prakash. 1994. Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites. Genes Dev. 8, 811-820.
3. Bailly, V., S. Prakash, and L. Prakash. 1997. Domains required for dimerization of yeast Rad6 ubiquitin-conjugating enzyme and Rad18 DNA-binding protein. Mol. Cell. Biol. 17, 4536-4543.
4. Chae, S.-K. and E. Kafer. 1993. uvsI mutants defective in UV mutagenesis define a fourth epistatic group of uvs genes in Aspergillus. Curr. Genet. 24, 67-74.
5. Dohmen, R.J., K. Madura, B. Bartel, and A. Varshavsky. 1991. The N-end rule is mediated by the UBC2 (RAD6) ubiquitin-conjugating enzyme. Proc. Natl. Acad. Sci. U.S.A. 88, 7351-7355.
6. Friedberg, E.C. 1988. Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae. Microbiol Rev. 52, 70-102.
7. Goldman, G.H., S.L. McGuire, and S.D. Harris. 2002. The DNA damage response in filamentous fungi. Fungal. Genet. Biol. 35, 183-195.
8. Hoege, C., B. Pfander, GL. Moldovan, G. Pyrowolakis, and S. Jentsch. 2002. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419, 135-141.
9. Huang, H., A. Kahana, D.E. Gottschling, L. Prakash, and S.W. Liebman. 1997. The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae. Mol. Cell. Biol. 17, 6693-6699.
10. Ito, H., Y. Fukada, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
11. Jacinto, E., B. Guo, K.T. Arndt, T. Schmelzle, and M.N. Hall. 2001. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Mol. Cell. 8, 1017-1026.
12. Jang, Y.-K., E. Kafer, and S.-K. Chae. 2001. Effects of uvsJ, a rad6 homolog, on mutagenesis in Aspergillus nidulans. Asilomar Fungal Genetics Conference. Abstract No. 377.
13. Kafer, E. 1977. Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv. Genet. 19, 33-131.
14. Kafer, E., and O. Mayor. 1986. Genetic analysis of DNA repair in Aspergillus: evidence for differrent types of MMS sensitive hyper-rec mutants. Mutat. Res. 161, 119-134.
15. Kafer, E., and G.S. May. 1998. Toward repair pathways in Aspergillus nidulans. In: J.A. Nickoloff, and M.F. Hoekstra, Editors, DNA Damage and Repair, Humana Press, Totowa. 477-502.
16. Lawrence, C.W, and R. Christensen. 1976. UV-mutagenesis in radiation-sensitive strains of yeast. Genetics. 82, 207-232.
17. Matunis, M.J. 2002. On the road to repair. PCNA encounters SUMO and ubiquitin modifications. Mol. Cell. 10, 441-442.
18. Morrison, A., E.J. Miller, and L. Prakash. 1988. Domain structure and functional analysis of the carboxyl-terminal polyacidic sequence of the RAD6 protein of Saccharomyces cerevisiae. Mol. Cell. Biol. 8, 1179-1185.
19. Robzyk, K., J. Recht, and M.A. Osley. 2000. Rad6-dependent ubiquitination of histone H2B in yeast. Science 287, 501-504.
20. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1992. Molecular Cloning: A Laboratory Manual, 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
21. Sun, Z.W., and C.D. Allis. 2002. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418, 104-108.
22. Sung, P., S. Prakash, and L. Prakash. 1990. Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions. Proc. Natl. Acad. Sci. U.S.A. 87, 2695-2699.