메뉴 건너뛰기




Volumn 77, Issue 5, 2003, Pages 1112-1118

Twenty-four-hour plasma tryptophan concentrations and ratios are below normal in obese subjects and are not normalized by substantial weight reduction

Author keywords

Insulin; Large neutral amino acids; Obesity; Plasma tryptophan; Serotonin; Very low energy diet; Weight loss

Indexed keywords

INSULIN; PHENYLALANINE; TRYPTOPHAN; TYROSINE; AMINO ACID; SEROTONIN;

EID: 0037797304     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/77.5.1112     Document Type: Article
Times cited : (65)

References (41)
  • 1
    • 0023264541 scopus 로고
    • Neuropharmacology of drugs affecting food intake
    • Sugrue MF. Neuropharmacology of drugs affecting food intake. Pharmacol Ther 1987;32:145-82.
    • (1987) Pharmacol Ther , vol.32 , pp. 145-182
    • Sugrue, M.F.1
  • 2
    • 0033914588 scopus 로고    scopus 로고
    • Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats
    • Vickers SP, Benwell KR, Porter RH, Bickerdike MJ, Kennett GA, Dourish CT. Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats. Br J Pharmacol 2000;130:1305-14.
    • (2000) Br J Pharmacol , vol.130 , pp. 1305-1314
    • Vickers, S.P.1    Benwell, K.R.2    Porter, R.H.3    Bickerdike, M.J.4    Kennett, G.A.5    Dourish, C.T.6
  • 3
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • Sze JY, Victor M, Loer C, Shi Y, Ruvkun G. Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 2000;403:560-4.
    • (2000) Nature , vol.403 , pp. 560-564
    • Sze, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvkun, G.5
  • 4
    • 0032962859 scopus 로고    scopus 로고
    • Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice
    • (Berl)
    • Vickers SP, Clifton PG, Dourish CT, Tecott LH. Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice. Psychopharmacology (Berl) 1999;143:309-14.
    • (1999) Psychopharmacology , vol.143 , pp. 309-314
    • Vickers, S.P.1    Clifton, P.G.2    Dourish, C.T.3    Tecott, L.H.4
  • 5
    • 0021712027 scopus 로고
    • Serotonin and appetite
    • Blundell JE. Serotonin and appetite. Neuropharmacology 1984;23:1537-51.
    • (1984) Neuropharmacology , vol.23 , pp. 1537-1551
    • Blundell, J.E.1
  • 6
    • 0022476591 scopus 로고
    • Serotoninergic mechanisms in human feeding: The pharmacological evidence
    • Silverstone T, Goodall E. Serotoninergic mechanisms in human feeding: the pharmacological evidence. Appetite 1986;7(suppl):85-97.
    • (1986) Appetite , vol.7 , Issue.SUPPL. , pp. 85-97
    • Silverstone, T.1    Goodall, E.2
  • 7
    • 0015526241 scopus 로고
    • Brain serotonin content: Physiological regulation by plasma neutral amino acids
    • Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science 1972;178:414-6.
    • (1972) Science , vol.178 , pp. 414-416
    • Fernstrom, J.D.1    Wurtman, R.J.2
  • 8
    • 0016715315 scopus 로고
    • Kinetic analysis of blood-brain barrier transport of amino acids
    • Pardridge WM, Oldendorf WH. Kinetic analysis of blood-brain barrier transport of amino acids. Biochim Biophys Acta 1975;401:128-36.
    • (1975) Biochim Biophys Acta , vol.401 , pp. 128-136
    • Pardridge, W.M.1    Oldendorf, W.H.2
  • 9
    • 0025012242 scopus 로고
    • Aromatic amino acids and monoamine synthesis in the central nervous system: Influence of the diet
    • Fernstrom JD. Aromatic amino acids and monoamine synthesis in the central nervous system: influence of the diet. J Nutr Biochem 1990;1:508-17.
    • (1990) J Nutr Biochem , vol.1 , pp. 508-517
    • Fernstrom, J.D.1
  • 10
    • 0028852487 scopus 로고
    • Brain tryptophan concentrations and serotonin synthesis remain responsive to food consumption after the ingestion of sequential meals
    • Fernstrom MH, Fernstrom JD. Brain tryptophan concentrations and serotonin synthesis remain responsive to food consumption after the ingestion of sequential meals. Am J Clin Nutr 1995;61:312-9.
    • (1995) Am J Clin Nutr , vol.61 , pp. 312-319
    • Fernstrom, M.H.1    Fernstrom, J.D.2
  • 11
    • 0023904645 scopus 로고
    • Plasma amino acids and insulin levels in obesity: Response to carbohydrate intake and tryptophan supplements
    • Caballero B, Finer N, Wurtman RJ. Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. Metabolism 1988;37:672-6.
    • (1988) Metabolism , vol.37 , pp. 672-676
    • Caballero, B.1    Finer, N.2    Wurtman, R.J.3
  • 12
    • 0022366113 scopus 로고
    • Evidence for diminished brain 5-hydroxytryptamine biosynthesis in obese diabetic and non-diabetic humans
    • Ashley DV, Fleury MO, Golay A, Maeder E, Leathwood PD. Evidence for diminished brain 5-hydroxytryptamine biosynthesis in obese diabetic and non-diabetic humans. Am J Clin Nutr 1985;42:1240-5.
    • (1985) Am J Clin Nutr , vol.42 , pp. 1240-1245
    • Ashley, D.V.1    Fleury, M.O.2    Golay, A.3    Maeder, E.4    Leathwood, P.D.5
  • 15
    • 0033629395 scopus 로고    scopus 로고
    • Long-term maintenance of weight loss: Current status
    • Jeffery RW, Drewnowski A, Epstein LH, et al. Long-term maintenance of weight loss: current status. Health Psychol 2000;19:5-16.
    • (2000) Health Psychol , vol.19 , pp. 5-16
    • Jeffery, R.W.1    Drewnowski, A.2    Epstein, L.H.3
  • 16
    • 0020662893 scopus 로고
    • Effect of experimental diabetes on the levels of aromatic and branched-chain amino acids in rat blood and brain
    • Crandall EA, Fernstrom JD. Effect of experimental diabetes on the levels of aromatic and branched-chain amino acids in rat blood and brain. Diabetes 1983;32:222-30.
    • (1983) Diabetes , vol.32 , pp. 222-230
    • Crandall, E.A.1    Fernstrom, J.D.2
  • 17
    • 0027952744 scopus 로고
    • The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects
    • Rice DE, Flakoll PJ, May MM, Hill JO, Abumrad NN. The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects. Metabolism 1994;43:211-6.
    • (1994) Metabolism , vol.43 , pp. 211-216
    • Rice, D.E.1    Flakoll, P.J.2    May, M.M.3    Hill, J.O.4    Abumrad, N.N.5
  • 18
    • 0029924108 scopus 로고    scopus 로고
    • Insulin and hyperaminoacidemia regulate by a different mechanism leucine turnover and oxidation in obesity
    • Luzi L, Castellino P, DeFronzo RA. Insulin and hyperaminoacidemia regulate by a different mechanism leucine turnover and oxidation in obesity. Am J Physiol 1996;270:E273-81.
    • (1996) Am J Physiol , vol.270
    • Luzi, L.1    Castellino, P.2    DeFronzo, R.A.3
  • 19
    • 0019435550 scopus 로고
    • Normal valine disposal in obese subjects with impaired glucose disposal: Evidence for selective insulin resistance
    • Glass AR, Bongiovanni R, Smith CE, Boehm TM. Normal valine disposal in obese subjects with impaired glucose disposal: evidence for selective insulin resistance. Metabolism 1981;30:578-82.
    • (1981) Metabolism , vol.30 , pp. 578-582
    • Glass, A.R.1    Bongiovanni, R.2    Smith, C.E.3    Boehm, T.M.4
  • 20
    • 0026003658 scopus 로고
    • Differential effects of insulin resistance on leucine and glucose kinetics in obesity
    • Caballero B, Wurtman RJ. Differential effects of insulin resistance on leucine and glucose kinetics in obesity. Metabolism 1991;40:51-8.
    • (1991) Metabolism , vol.40 , pp. 51-58
    • Caballero, B.1    Wurtman, R.J.2
  • 21
    • 0028315970 scopus 로고
    • Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin-dependent diabetes
    • Pijl H, Potter van Loon BJ, Toornvliet AC, et al. Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin-dependent diabetes. Metabolism 1994;43:640-6.
    • (1994) Metabolism , vol.43 , pp. 640-646
    • Pijl, H.1    Potter Van Loon, B.J.2    Toornvliet, A.C.3
  • 22
    • 0028953083 scopus 로고
    • Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
    • Rasmussen MH, Hvidberg A, Juul A, et al. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects. J Clin Endocrinol Metab 1995;80:1407-15.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1407-1415
    • Rasmussen, M.H.1    Hvidberg, A.2    Juul, A.3
  • 23
    • 0023634780 scopus 로고
    • Formula diet plus free additional food choice up to 103 kcal (4.2 MJ) compared with an isoenergetic conventional diet in the treatment of obesity
    • Hey H, Petersen HD, Andersen T, Quaade F. Formula diet plus free additional food choice up to 103 kcal (4.2 MJ) compared with an isoenergetic conventional diet in the treatment of obesity. Clin Nutr 1986;6:195-9.
    • (1986) Clin Nutr , vol.6 , pp. 195-199
    • Hey, H.1    Petersen, H.D.2    Andersen, T.3    Quaade, F.4
  • 24
    • 10244278601 scopus 로고    scopus 로고
    • Anthropometric indices of obesity and regional distribution of fat depots
    • Bjorntorp P, ed. Chichester, United Kingdom: John Wiley
    • Han TS, Lean MEJ. Anthropometric indices of obesity and regional distribution of fat depots. In: Bjorntorp P, ed. International textbook of obesity. Chichester, United Kingdom: John Wiley, 2001:51-65.
    • (2001) International Textbook of Obesity , pp. 51-65
    • Han, T.S.1    Lean, M.E.J.2
  • 25
    • 0014035240 scopus 로고
    • Determination of tryptophan in plasma, liver and urine
    • Denckla WD, Dewey HK. Determination of tryptophan in plasma, liver and urine. J Lab Clin Med 1967;69:160-9.
    • (1967) J Lab Clin Med , vol.69 , pp. 160-169
    • Denckla, W.D.1    Dewey, H.K.2
  • 26
    • 0015122452 scopus 로고
    • Light - A source of error in the fluorometric determination of tryptophan
    • Lehmann J. Light - A source of error in the fluorometric determination of tryptophan. Scand J Clin Lab Invest 1971;28:49-55.
    • (1971) Scand J Clin Lab Invest , vol.28 , pp. 49-55
    • Lehmann, J.1
  • 27
    • 0016168683 scopus 로고
    • Error in the determination of tryptophan by the method of Denckla and Dewey. a revised procedure
    • Bloxam DL, Warren WH. Error in the determination of tryptophan by the method of Denckla and Dewey. A revised procedure. Anal Biochem 1974;60:621-5.
    • (1974) Anal Biochem , vol.60 , pp. 621-625
    • Bloxam, D.L.1    Warren, W.H.2
  • 29
    • 0026374634 scopus 로고
    • Body fat in the adult Danish population aged 35-65 years: An epidemiological study
    • Heitmann BL. Body fat in the adult Danish population aged 35-65 years: an epidemiological study. Int J Obes 1991;15:535-45.
    • (1991) Int J Obes , vol.15 , pp. 535-545
    • Heitmann, B.L.1
  • 30
    • 0018687475 scopus 로고
    • Diurnal variations in plasma concentrations of tryptophan, tyrosine, and other neutral amino acids: Effect of dietary protein intake
    • Fernstrom JD, Wurtman RJ, Hammarstrom Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma concentrations of tryptophan, tyrosine, and other neutral amino acids: effect of dietary protein intake. Am J Clin Nutr 1979;32:1912-22.
    • (1979) Am J Clin Nutr , vol.32 , pp. 1912-1922
    • Fernstrom, J.D.1    Wurtman, R.J.2    Hammarstrom Wiklund, B.3    Rand, W.M.4    Munro, H.N.5    Davidson, C.S.6
  • 31
    • 0024948545 scopus 로고
    • Diurnal rhythm in absolute and relative concentrations of large neutral amino acids in human plasma
    • Eriksson T, Voog L, Walinder J, Eriksson TE. Diurnal rhythm in absolute and relative concentrations of large neutral amino acids in human plasma. J Psychiatr Res 1989;23:241-9.
    • (1989) J Psychiatr Res , vol.23 , pp. 241-249
    • Eriksson, T.1    Voog, L.2    Walinder, J.3    Eriksson, T.E.4
  • 32
    • 0014429847 scopus 로고
    • Daily rhythms in the concentrations of various amino acids in human plasma
    • Wurtman RJ, Rose CM, Chou C, Larin FF. Daily rhythms in the concentrations of various amino acids in human plasma. N Engl J Med 1968;279:171-5.
    • (1968) N Engl J Med , vol.279 , pp. 171-175
    • Wurtman, R.J.1    Rose, C.M.2    Chou, C.3    Larin, F.F.4
  • 33
    • 0018755338 scopus 로고
    • Factors affecting plasma amino acid concentrations in control subjects
    • Milsom JP, Morgan MY, Sherlock S. Factors affecting plasma amino acid concentrations in control subjects. Metabolism 1979;28:313-9.
    • (1979) Metabolism , vol.28 , pp. 313-319
    • Milsom, J.P.1    Morgan, M.Y.2    Sherlock, S.3
  • 34
    • 0020609686 scopus 로고
    • The treatment of obesity by carbohydrate deprivation suppresses plasma tryptophan and its ratio to other large neutral amino acids
    • Heraief E, Burckhardt P, Mauron C, Wurtman JJ, Wurtman RJ. The treatment of obesity by carbohydrate deprivation suppresses plasma tryptophan and its ratio to other large neutral amino acids. J Neural Transm 1983;57:187-95.
    • (1983) J Neural Transm , vol.57 , pp. 187-195
    • Heraief, E.1    Burckhardt, P.2    Mauron, C.3    Wurtman, J.J.4    Wurtman, R.J.5
  • 35
    • 0027227938 scopus 로고
    • Evidence for brain serotonin-mediated control of carbohydrate consumption in normal weight and obese humans
    • Pijl H, Koppeschaar HPF, Cohen AF, et al. Evidence for brain serotonin-mediated control of carbohydrate consumption in normal weight and obese humans. Int J Obes Relat Metab Disord 1993;17:513-20.
    • (1993) Int J Obes Relat Metab Disord , vol.17 , pp. 513-520
    • Pijl, H.1    Koppeschaar, H.P.F.2    Cohen, A.F.3
  • 36
    • 0030034197 scopus 로고    scopus 로고
    • Long-term effect of dexfenfluramine on amino acid profiles and food selection in obese patients during weight loss
    • Breum L, Moller SE, Andersen T, Astrup A. Long-term effect of dexfenfluramine on amino acid profiles and food selection in obese patients during weight loss. Int J Obes Relat Metab Disord 1996;20:147-53.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 147-153
    • Breum, L.1    Moller, S.E.2    Andersen, T.3    Astrup, A.4
  • 37
    • 0018717910 scopus 로고
    • Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: Effect of dietary protein
    • Fernstrom JD, Wurtman RJ, Hammarstrom Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein. Am J Clin Nutr 1979;32:1923-33.
    • (1979) Am J Clin Nutr , vol.32 , pp. 1923-1933
    • Fernstrom, J.D.1    Wurtman, R.J.2    Hammarstrom Wiklund, B.3    Rand, W.M.4    Munro, H.N.5    Davidson, C.S.6
  • 38
    • 0021968646 scopus 로고
    • The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes
    • Salter M, Pogson CI. The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes. Biochem J 1985;229:499-504.
    • (1985) Biochem J , vol.229 , pp. 499-504
    • Salter, M.1    Pogson, C.I.2
  • 40
  • 41
    • 0025613807 scopus 로고
    • Serotonin and appetite
    • Curzon G. Serotonin and appetite. Ann N Y Acad Sci 1990;600:521-30.
    • (1990) Ann N Y Acad Sci , vol.600 , pp. 521-530
    • Curzon, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.