Effects of genetic polymorphisms in metabolic enzymes on the relationships between 8-hydroxydeoxyguanosine levels in human leukocytes and urinary 1-hydroxypyrene and 2-naphthol concentrations

Journal of Occupational Health

Volumn 45, Issue 3, 2003, Pages 160-167

  Kim, Yong Dae ^a   Lee, Chul Ho ^a   Nan, Hong Mei ^a   Kang, Jong Won ^a   Kim, Heon ^a  

^a Chungbuk National University College of Medicine   (South Korea)

Author keywords

1 hydroxypyrene; 2 naphthol; 8 hydroxydeoxyguanosine; Metabolic enzyme; Polymorphism

Indexed keywords

1 HYDROXYPYRENE; 2 NAPHTHOL; 8 HYDROXYDEOXYGUANOSINE; ACYLTRANSFERASE; ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; ENZYME; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A6; GLUTATHIONE TRANSFERASE M1; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CIGARETTE SMOKING; CORRELATION ANALYSIS; ENVIRONMENTAL EXPOSURE; GENETIC POLYMORPHISM; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEUKOCYTE; MALE; METABOLISM; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; URINALYSIS; URINE LEVEL; WILD TYPE;

ARYLAMINE N-ACETYLTRANSFERASE; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2E1; GENOTYPE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GUANINE; HUMANS; LEUKOCYTES; MALE; NAPHTHOLS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PYRENES; REGRESSION ANALYSIS; SMOKING;

EID: 0037787809     PISSN: 13419145     EISSN: None     Source Type: Journal    
DOI: 10.1539/joh.45.160     Document Type: Article

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