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Volumn 46, Issue 7, 2003, Pages 645-659
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Synthesis and evaluation of 5,7-dichloro-4-(3-{4-[4-(2-[18F]fluoroethyl)-piperazin-1-yl]- phenyl}-ureido)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivo
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Author keywords
18F fluoroalkylation; Glutamate; Glycine binding site; NMDA receptor
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Indexed keywords
BINDING ENERGY;
BINDING SITES;
BONE;
CARBOXYLIC ACIDS;
DIAGNOSIS;
ESTERS;
LIGANDS;
NEURODEGENERATIVE DISEASES;
POSITRON EMISSION TOMOGRAPHY;
18F-FLUOROALKYLATION;
BINDING-SITES;
BIODISTRIBUTIONS;
FLUOROALKYLATION;
GLUTAMATE;
GLYCINE BINDING SITE;
IN-VIVO;
METHYL ESTERS;
NMDA RECEPTOR;
TETRAHYDROQUINOLINES;
AMINO ACIDS;
3 (2 CARBOXY 2 PHENYLETHENYL) 4,6 DICHLORO 1H INDOLE 2 CARBOXYLIC ACID;
5,7 DICHLORO 4 [3 (4 PIPERAZIN 1 YLPHENYL)UREIDO] 1,2,3,4 TETRAHYDROQUINOLINE 2 CARBOXYLIC ACID;
5,7 DICHLORO 4 [3 [4 [4 (2 FLUOROETHYL)PIPERAZIN 1 YL]PHENYL]UREIDO] 1,2,3,4 TETRAHYDROQUINOLINE 2 CARBOXYLIC ACID F 18;
CARBOXYLIC ACID DERIVATIVE;
ESTER;
FLUORINE DERIVATIVE;
FLUOROETHYLTOSYLATE F 18;
GLUTAMIC ACID;
LIGAND;
N METHYL DEXTRO ASPARTIC ACID RECEPTOR;
N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL TISSUE;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
BRAIN CORTEX;
CONTROLLED STUDY;
DIAGNOSTIC TEST;
DRUG BONE LEVEL;
DRUG BRAIN LEVEL;
DRUG DETERMINATION;
DRUG DISTRIBUTION;
DRUG LIVER LEVEL;
DRUG RECEPTOR BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG UPTAKE;
IN VITRO STUDY;
IN VIVO STUDY;
ISOTOPE LABELING;
LIPOPHILICITY;
NEUROTRANSMISSION;
NONHUMAN;
POSITRON EMISSION TOMOGRAPHY;
RAT;
SUS SCROFA;
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EID: 0037787767
PISSN: 03624803
EISSN: None
Source Type: Journal
DOI: 10.1002/jlcr.682 Document Type: Article |
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Times cited : (15)
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References (18)
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