Bioactive peptidic analogues and cyclostereoisomers of the minimal antinociceptive histogranin fragment-(7-10)

Journal of Medicinal Chemistry

Volumn 46, Issue 14, 2003, Pages 3094-3101

  Le, Hoang Thanh ^a   Lemaire, Irma B ^a   Gilbert, Annie Kim ^b   Jolicoeur, François ^b   Lemaire, Simon ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINOCICEPTIVE AGENT; CYCLO(GLYCYL 4 CHLOROPHENYLALANYLTYROSYL DEXTRO ARGININE); CYCLO(GLYCYLALANYLTYROSYL DEXTRO ARGININE); DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; FREUND ADJUVANT; HISTOGRANIN[7-10]; NALOXONE; OPIATE ANTAGONIST; PEPTIDE DERIVATIVE; RACLOPRIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BRAIN MEMBRANE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYCLIZATION; DRUG EFFICACY; DRUG POTENCY; HYPERALGESIA; INFLAMMATION; LIPOPHILICITY; MOTOR ACTIVITY; MOUSE; NONHUMAN; RAT; STEREOISOMERISM; TAIL FLICK TEST; WRITHING TEST;

ANALGESICS; ANIMALS; BRAIN; MALE; MICE; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; PEPTIDES, CYCLIC; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037784002     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0300734     Document Type: Article

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