Unintentional pediatric overdose of propafenone [5]

Annals of Pharmacotherapy

Volumn 37, Issue 7-8, 2003, Pages 1147-1148

  Molia, Aurélie C ^a   Tholon, Jean Pierre ^b   Lamiable, Denis L ^a   Trenque, Thierry C ^a  

^a REIMS UNIVERSITY HOSPITAL   (France)

^b Pediatric Department   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROPAFENONE;

BRADYCARDIA; CARDIOTOXICITY; CASE REPORT; CHILDHOOD DISEASE; CONCENTRATION RESPONSE; CYANOSIS; DOSE RESPONSE; DRUG OVERDOSE; ELECTROCARDIOGRAM; HEART ARREST; HEART ARRHYTHMIA; HUMAN; HYPOTENSION; LETTER; MALE; NAUSEA; PRESCHOOL CHILD; PRIORITY JOURNAL; QT INTERVAL; SEIZURE; SHOCK; VOMITING;

EID: 0037781953     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1C479     Document Type: Letter

References (6)

1. Winek CL, Wahba WW, Winek CL Jr, Balzer TW. Drug and chemical blood-level data 2001. Forensic Sci Int 2001;122:107-23.
2. Musto B, D'Onofrio A, Cavallaro C, Musto A. Electrophysiological effects and clinical efficacy of propafenone in children with recurrent paroxysmal supraventricular tachycardia. Circulation 1988;78:863-9.
3. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
4. McHugh TP, Perina DG. Propafenone ingestion. Ann Emerg Med 1987;16:437-40.
5. Köppel C, Oberdisse U, Heinemeyer G. Clinical course and outcome in class IC antiarrhythmic overdose. J Tox Clin Toxicol 1990;28:433-44.
6. Fonck K, Haenebalcke C, Hemeryck A, Belpaire F, Jordaens L, Calle P, et al. ECG changes and plasma concentrations of propafenone and its metabolites in a case of severe poisoning. J Tox Clin Toxicol 1998;36:247-51.