Abnormal regulation of DNA methyltransferase expression in cloned mouse embryos

Biology of Reproduction

Volumn 69, Issue 1, 2003, Pages 146-153

  Chung, Young Gie ^a   Ratnam, Sarayu ^b   Chaillet, J Richard ^b,c   Latham, Keith E ^a,d  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d FOX CHASE CANCER CENTER   (United States)

Author keywords

Developmental biology; Early development; Embryo; Gene regulation

Indexed keywords

DNA (CYTOSINE 5) METHYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL NUCLEUS TRANSPLANTATION; CELLULAR DISTRIBUTION; CLONING; CONTROLLED STUDY; CYTOPLASM; DEVELOPMENTAL BIOLOGY; DEVELOPMENTAL DISORDER; DNA METHYLATION; EMBRYO; EMBRYO DEVELOPMENT; GENE CONTROL; NONHUMAN; OOCYTE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SOMATIC CELL;

ANIMALS; BLASTOCYST; CELL NUCLEUS; CLEAVAGE STAGE, OVUM; CLONING, ORGANISM; CYTOPLASM; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MORULA; MOSAICISM; NUCLEAR TRANSFER TECHNIQUES; PREGNANCY;

ANIMALIA; MAMMALIA;

EID: 0037775594     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.014076     Document Type: Article

References (28)

1. Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM III, Yanagimachi R, Jaenisch R. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complememation. Proc Natl Acad Sci U S A 2001; 98:6209-6214.
2. Tamashiro KL, Wakayama T, Blanchard RJ, Blanchard DC, Yanagimachi R. Postnatal growth and behavioral development of mice cloned from adult cumulus cells. Biol Reprod 2000; 63:328-334.
3. Tanaka S, Oda M, Toyoshima Y, Wakayama T, Tanaka M, Yoshida N, Hattori N, Ohgane J, Yanagimachi R, Shiota K. Placentomegaly in cloned mouse concepti caused by expansion of the spongiotrophoblast layer. Biol Reprod 2001; 65:1813-1821.
4. Renard JP, Chastant S, Chesne P, Richard C, Marchal J, Cordonnier N, Chavatte P, Vignon X. Lymphoid hypoplasia and somatic cloning. Lancet 1999; 353:1489-1491.
5. Chung YG, Mann MR, Bartolomei MS, Latham KE. Nuclear-cytoplasmic "tug-of-war" during cloning: effects of somatic cell nuclei on culture medium preferences of preimplantation cloned mouse embryos. Biol Reprod 2002; 66:1178-1184.
6. Boiani M, Eckardt S, Scholer HR, McLaughlin KJ. Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev 2002; 16:1209-1219.
7. Humpherys D, Eggan K, Akutsu H, Hochedlinger K, Rideout WM III, Biniszkiewicz D, Yanagimachi R, Jaenisch R. Epigenetic instability in ES cells and cloned mice. Science 2001; 293:95-97.
8. Ohgane J, Wakayama T, Kogo Y, Senda S, Hattori N, Tanaka S, Yanagimachi R, Shiota K. DNA methylation variation in cloned mice. Genesis 2001; 30:45-50.
9. Kang YK, Koo DB, Park JS, Choi YH, Chung AS, Lee KK, Han YM. Aberrant methylation of donor genome in cloned bovine embryos. Nat Genet 2001; 28:173-177.
10. Kang YK, Koo DB, Park JS, Choi YH, Kim HN, Chang WK, Lee KK, Han YM. Typical demethylation events in cloned pig embryos. Clues on species-specific differences in epigenetic reprogramming of a cloned donor genome. J Biol Chem 2001; 276:39980-39984.
11. Kang YK, Koo DB, Park JS, Choi YH, Lee KK, Han YM. Influence of oocyte nuclei on demethylation of donor genome in cloned bovine embryos. FEBS Lett 2001; 499:55-58.
12. Bourc'his D, Le Bourhis D, Patin D, Niveleau A, Comizzoli P, Renard J, Viegas-Pequignot E. Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos. Curr Biol 2001; 11:1542-1546.
13. Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001; 293:1089-1093.
14. Dean W, Santos F, Stojkovic M, Zakhartchenko V, Walter J, Wolf E, Reik W. Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc Natl Acad Sci U S A 2001; 98:13734-13738.
15. Ratnam S, Mertineit C, Ding F, Howell CY, Clarke HJ, Bestor TH, Chaillet JR, Trasler JM. Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and pre-implantation development. Dev Biol 2002; 245:304-314.
16. Howell CY, Bestor TH, Ding F, Latham KE, Mertineit C, Trasler JM, Chaillet JR. Genomic imprinting disrupted by a maternal effect mutation in the Dnmtl gene. Cell 2001; 104:829-838.
17. Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 1993; 366:362-365.
18. Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992 69:915-926.
19. Carlson LL, Page AW, Bestor TH. Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting. Genes Dev 1992; 6:2536-2541.
20. Mertineit C, Yoder JA, Taketo T, Laird DW, Trasler JM, Bestor TH. Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development 1998; 125:889-897.
21. Wakayama T, Perry ACF, Zuccotti M, Johnson KR, Yanagimachi R. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998; 394:369-374.
22. Wakayama T, Yanagimachi R. Effect of cytokinesis inhibitors, DMSO and the timing of oocyte activation on mouse cloning using cumulus cell nuclei. Reproduction 2001; 122:49-60.
23. Latham KE. Mechanisms and control of embryonic genome activation in mammalian embryos. Int Rev Cytol 1999; 19:71-124.
24. Kubiak JZ, Prather RS, Maul GG, Schatten G. Cytoplasmic modification of the nuclear lamina during pronuclear-like transformation of mouse blastomere nuclei. Mech Dev 1991; 35:103-111.
25. Szollosi D, Czolowska R, Soltynska MS, Tarkowski AK. Remodeling of thymocyte nuclei in activated mouse oocytes: an ultrastructural study. Eur J Cell Biol 1986; 42:140-151.
26. Czolowska R, Modlinski JA, Tarkowski AK. Behaviour of thymocyte nuclei in non-activated and activated mouse oocytes. J Cell Sci 1984; 69:19-34.
27. Park KW, Lai L, Cheong HT, Cabot R, Sun QY, Wu G, Rucker EB, Durtsch D, Bonk A, Samuel M, Rieke A, Day BN, Murphy CN, Carter DB, Prather RS. Mosaic gene expression in nuclear transfer-derived embryos and the production of cloned transgenic pigs from ear-derived fibroblasts. Biol Reprod 2002; 66:1001-1005.
28. Ding F, Chaillet JR. In vivo stabilization of the Dnmt1 (cytosine-5)methyltransferase protein. Proc Natl Acad Sci U S A 2002; 99:14861-14866.