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Volumn 23, Issue 2, 2003, Pages 395-411

Prenatal screening for Down syndrome: Current and future methods

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN;

EID: 0037772456     PISSN: 02722712     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-2712(03)00025-8     Document Type: Review
Times cited : (8)

References (59)
  • 1
    • 0038230327 scopus 로고    scopus 로고
    • Neural tube defects
    • Wald N, Leck I, editors, Oxford, UK: Oxford University Press
    • Wald N. Neural tube defects. In: Wald N, Leck I, editors, Antenatal and neonatal screening. 2nd edition, Oxford, UK: Oxford University Press; 2000. p. 61-84.
    • (2000) Antenatal and Neonatal Screening. 2nd Edition , pp. 61-84
    • Wald, N.1
  • 3
    • 0037554917 scopus 로고    scopus 로고
    • Preface to the second edition
    • Wald N, Leck I, editors. Oxford, UK: Oxford University Press
    • Wald N. Preface to the second edition. In: Wald N, Leck I, editors. Antenatal and neonatal screening. 2nd edition. Oxford, UK: Oxford University Press; 2000. p. xi-xii.
    • (2000) Antenatal and Neonatal Screening. 2nd Edition
    • Wald, N.1
  • 5
    • 0032424855 scopus 로고    scopus 로고
    • Natural history of Down's syndrome: A brief review for those involved in antenatal screening
    • Noble J. Natural history of Down's syndrome: a brief review for those involved in antenatal screening. J Med Screen 1998;5:172-7.
    • (1998) J Med Screen , vol.5 , pp. 172-177
    • Noble, J.1
  • 6
    • 0000197470 scopus 로고    scopus 로고
    • Down's syndrome
    • Wald N, Leck I, editors. Oxford, UK: Oxford University Press
    • Wald N. Down's syndrome. In: Wald N, Leck I, editors. Antenatal and neonatal screening. 2nd edition. Oxford, UK: Oxford University Press; 2000. p. 85-115.
    • (2000) Antenatal and Neonatal Screening. 2nd Edition , pp. 85-115
    • Wald, N.1
  • 7
    • 84951507059 scopus 로고
    • The relative effects of paternal and maternal age in mongolism
    • Penrose LS. The relative effects of paternal and maternal age in mongolism. J Genet 1933;27:219-24.
    • (1933) J Genet , vol.27 , pp. 219-224
    • Penrose, L.S.1
  • 9
    • 0038569078 scopus 로고
    • The detection of neural-tube defects by screening maternal blood
    • Boue A, editor. France: INSERM
    • Wald NJ. The detection of neural-tube defects by screening maternal blood. In: Boue A, editor. Prenatal diagnosis. France: INSERM; 1976. p. 227-38.
    • (1976) Prenatal Diagnosis , pp. 227-238
    • Wald, N.J.1
  • 10
    • 0021247504 scopus 로고
    • An association between low maternal serum alpha-fetoprotein and fetal chromosome abnormalities
    • Merkatz IR, Nitowsky HM, Macri JN, et al. An association between low maternal serum alpha-fetoprotein and fetal chromosome abnormalities. Am J Obstet Gynecol 1984;148:886-94.
    • (1984) Am J Obstet Gynecol , vol.148 , pp. 886-894
    • Merkatz, I.R.1    Nitowsky, H.M.2    Macri, J.N.3
  • 11
    • 0021248894 scopus 로고
    • Maternal serum alpha-fetoprotein measurement. A screening test for Down syndrome
    • Cuckle HS, Wald NJ, Lindenbaum RH. Maternal serum alpha-fetoprotein measurement. A screening test for Down syndrome. Lancet 1984;i:926-9.
    • (1984) Lancet , vol.1 , pp. 926-929
    • Cuckle, H.S.1    Wald, N.J.2    Lindenbaum, R.H.3
  • 12
    • 0024605347 scopus 로고
    • Combining maternal serum α feto-protein measurements and age to screen Down's syndrome in pregnant women under age 35
    • New England Regional Genetics Group Prenatal Collaborative Study of Down's Syndrome Screening. Combining maternal serum α feto-protein measurements and age to screen Down's syndrome in pregnant women under age 35. Am J Obstet Gynecol 1989;160:575-81.
    • (1989) Am J Obstet Gynecol , vol.160 , pp. 575-581
  • 13
    • 0031395671 scopus 로고    scopus 로고
    • Antenatal screening for Down's syndrome
    • Wald NJ, Kennard A, Hackshaw A, et al. Antenatal screening for Down's syndrome. J Med Screen 1997;4:181-246.
    • (1997) J Med Screen , vol.4 , pp. 181-246
    • Wald, N.J.1    Kennard, A.2    Hackshaw, A.3
  • 14
    • 0023801407 scopus 로고
    • Low second trimester maternal serum unconjugated estriol in pregnancies with Down's syndrome
    • Canick J, Knight GJ, Palomaki GE, et al. Low second trimester maternal serum unconjugated estriol in pregnancies with Down's syndrome. Br J Obstet Gynaecol 1988;95:330-3.
    • (1988) Br J Obstet Gynaecol , vol.95 , pp. 330-333
    • Canick, J.1    Knight, G.J.2    Palomaki, G.E.3
  • 15
    • 0023805058 scopus 로고
    • Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndrome
    • Wald NJ, Cuckle HS, Densem JW, et al. Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndrome. Br J Obstet Gynaecol 1988;95:334-41.
    • (1988) Br J Obstet Gynaecol , vol.95 , pp. 334-341
    • Wald, N.J.1    Cuckle, H.S.2    Densem, J.W.3
  • 16
    • 0023639762 scopus 로고
    • Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities
    • Bogart M, Pandian MR, Jones OW. Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities. Prenat Diagn 1987;7:623-30.
    • (1987) Prenat Diagn , vol.7 , pp. 623-630
    • Bogart, M.1    Pandian, M.R.2    Jones, O.W.3
  • 17
    • 0023726523 scopus 로고
    • Maternal serum screening for Down's syndrome in early pregnancy
    • Wald NJ, Cuckle HS, Densem JW, et al. Maternal serum screening for Down's syndrome in early pregnancy. BMJ 1988;297:883-97.
    • (1988) BMJ , vol.297 , pp. 883-897
    • Wald, N.J.1    Cuckle, H.S.2    Densem, J.W.3
  • 18
    • 0025145184 scopus 로고
    • Maternal serum Down syndrome screening: Free beta-protein is a more effective marker than human chorionic gonadotropin
    • Macri JN, Kasturi RV, Krantz DA, et al. Maternal serum Down syndrome screening: free beta-protein is a more effective marker than human chorionic gonadotropin. Am J Obstet Gynecol 1990;163:1248-53.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 1248-1253
    • Macri, J.N.1    Kasturi, R.V.2    Krantz, D.A.3
  • 20
    • 0029869141 scopus 로고    scopus 로고
    • Dimeric inhibin-A as a marker for Down's syndrome in early pregnancy
    • Aitken DA, Wallace EM, Crossley JA, et al. Dimeric inhibin-A as a marker for Down's syndrome in early pregnancy. N Engl J Med 1996;334:1231-6.
    • (1996) N Engl J Med , vol.334 , pp. 1231-1236
    • Aitken, D.A.1    Wallace, E.M.2    Crossley, J.A.3
  • 21
    • 0031911764 scopus 로고    scopus 로고
    • hCG and the free β-subunit as screening tests for Down syndrome
    • Knight GJ, Palomaki GE, Neveux L, et al. hCG and the free β-subunit as screening tests for Down syndrome. Prenat Diagn 1998;18:235-46.
    • (1998) Prenat Diagn , vol.18 , pp. 235-246
    • Knight, G.J.1    Palomaki, G.E.2    Neveux, L.3
  • 22
    • 0033851451 scopus 로고    scopus 로고
    • Assay precision of serum α fetoprotein in antenatal screening for neural tube defects and Down's syndrome
    • Wald NJ, Hackshaw AK, George LM. Assay precision of serum α fetoprotein in antenatal screening for neural tube defects and Down's syndrome. J Med Screen 2000;7:74-7.
    • (2000) J Med Screen , vol.7 , pp. 74-77
    • Wald, N.J.1    Hackshaw, A.K.2    George, L.M.3
  • 23
    • 0031030481 scopus 로고    scopus 로고
    • Chorionic villus sampling and amniocentesis for prenatal diagnosis
    • Stranc LC, Evans JA, Hamerton JL. Chorionic villus sampling and amniocentesis for prenatal diagnosis. Lancet 1997;349:711-4.
    • (1997) Lancet , vol.349 , pp. 711-714
    • Stranc, L.C.1    Evans, J.A.2    Hamerton, J.L.3
  • 24
    • 0027495486 scopus 로고
    • Serum alpha-fetoprotein and neural tube defects in the first trimester of pregnancy
    • Wald NJ, Hackshaw A, Stone R, et al. Serum alpha-fetoprotein and neural tube defects in the first trimester of pregnancy. Prenat Diagn 1993;13:1047-50.
    • (1993) Prenat Diagn , vol.13 , pp. 1047-1050
    • Wald, N.J.1    Hackshaw, A.2    Stone, R.3
  • 25
    • 0032730674 scopus 로고    scopus 로고
    • First trimester screening for aneuploidy: Serum biochemical markers
    • Canick JA, Kellner LH. First trimester screening for aneuploidy: serum biochemical markers. Semin Perinat 1999;23:359-68.
    • (1999) Semin Perinat , vol.23 , pp. 359-368
    • Canick, J.A.1    Kellner, L.H.2
  • 26
    • 0030883821 scopus 로고    scopus 로고
    • Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome
    • Wald NJ, Hackshaw AK. Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome. Prenat Diagn 1997;17:821-30.
    • (1997) Prenat Diagn , vol.17 , pp. 821-830
    • Wald, N.J.1    Hackshaw, A.K.2
  • 27
    • 0026748639 scopus 로고
    • Free β-hCG as a first trimester marker for fetal trisomy
    • Spencer K, Macri JN, Aitken DA, Connor JM. Free β-hCG as a first trimester marker for fetal trisomy. Lancet 1992;339:1480.
    • (1992) Lancet , vol.339 , pp. 1480
    • Spencer, K.1    Macri, J.N.2    Aitken, D.A.3    Connor, J.M.4
  • 28
    • 0027483421 scopus 로고
    • Low maternal serum levels of PAPP-A in the first trimester in association with abnormal fetal karyotype
    • Brambati B, Macintosh MCM, Teisner B. Low maternal serum levels of PAPP-A in the first trimester in association with abnormal fetal karyotype. Br J Obstet Gynaecol 1993;100:324-6.
    • (1993) Br J Obstet Gynaecol , vol.100 , pp. 324-326
    • Brambati, B.1    Macintosh, M.C.M.2    Teisner, B.3
  • 29
    • 0025165471 scopus 로고
    • Nuchal fluid accumulation in trisomy 21 detected by vaginosonography in first trimester
    • Szabo J, Gellen J. Nuchal fluid accumulation in trisomy 21 detected by vaginosonography in first trimester. Lancet 1990;336:1133.
    • (1990) Lancet , vol.336 , pp. 1133
    • Szabo, J.1    Gellen, J.2
  • 30
    • 0026562612 scopus 로고
    • Fetal nuchal translucency: Ultrasound screening for chromosomal defects in first trimester of pregnancy
    • Nicolaides KH, Azar G, Byrne D, et al. Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy. BMJ 1992;304:867-9.
    • (1992) BMJ , vol.304 , pp. 867-869
    • Nicolaides, K.H.1    Azar, G.2    Byrne, D.3
  • 31
    • 0038229773 scopus 로고    scopus 로고
    • Ultrasound in obstetrics and gynecology: An imaging revolution
    • D'Alton ME. Ultrasound in obstetrics and gynecology: an imaging revolution. Contemp Obstet Gynecol 1998;43:67-84.
    • (1998) Contemp Obstet Gynecol , vol.43 , pp. 67-84
    • D'Alton, M.E.1
  • 33
    • 0029792138 scopus 로고    scopus 로고
    • Nuchal translucency cannot be used as a screening test for chromosome abnormalities in the first trimester of pregnancy in a routine ultrasound practice
    • Kornman LH, Morssink LP, Beekhuis JR, et al. Nuchal translucency cannot be used as a screening test for chromosome abnormalities in the first trimester of pregnancy in a routine ultrasound practice. Prenat Diagn 1996;16:797-806.
    • (1996) Prenat Diagn , vol.16 , pp. 797-806
    • Kornman, L.H.1    Morssink, L.P.2    Beekhuis, J.R.3
  • 34
    • 0032833266 scopus 로고    scopus 로고
    • Effect of study design on the association between nuchal translucency measurement and Down syndrome
    • Mol BWJ, Lijmer JG, van der Meulen J, et al. Effect of study design on the association between nuchal translucency measurement and Down syndrome. Obstet Gynecol 1999;94:864-9.
    • (1999) Obstet Gynecol , vol.94 , pp. 864-869
    • Mol, B.W.J.1    Lijmer, J.G.2    Van der Meulen, J.3
  • 35
    • 0032473926 scopus 로고    scopus 로고
    • Screening of maternal serum for fetal Down's syndrome in the first trimester
    • Haddow JE, Palomaki GE, Knight GJ, et al. Screening of maternal serum for fetal Down's syndrome in the first trimester. N Engl J Med 1998;338:955-61.
    • (1998) N Engl J Med , vol.338 , pp. 955-961
    • Haddow, J.E.1    Palomaki, G.E.2    Knight, G.J.3
  • 36
    • 0032753392 scopus 로고    scopus 로고
    • First trimester screening for aneuploidy: Nuchal translucency sonography
    • Stewart TL, Malone FD. First trimester screening for aneuploidy: nuchal translucency sonography. Semin Perinat 1999;23:369-81.
    • (1999) Semin Perinat , vol.23 , pp. 369-381
    • Stewart, T.L.1    Malone, F.D.2
  • 39
    • 0034075495 scopus 로고    scopus 로고
    • Participation in maternal serum screening following screen positive results in a previous pregnancy
    • Rausch DN, Lambert-Messerlian GM, Canick JA. Participation in maternal serum screening following screen positive results in a previous pregnancy. J Med Screen 2000;7:4-6.
    • (2000) J Med Screen , vol.7 , pp. 4-6
    • Rausch, D.N.1    Lambert-Messerlian, G.M.2    Canick, J.A.3
  • 40
    • 0033549839 scopus 로고    scopus 로고
    • Integrated screening for Down's syndrome based on tests performed during the first and second trimesters
    • Wald NJ, Watt HC, Hackshaw AK. Integrated screening for Down's syndrome based on tests performed during the first and second trimesters. N Engl J Med 1999;341:461-7.
    • (1999) N Engl J Med , vol.341 , pp. 461-467
    • Wald, N.J.1    Watt, H.C.2    Hackshaw, A.K.3
  • 41
    • 0020696212 scopus 로고
    • Chromosomal abnormality rates at amniocentesis and in live-born infants
    • Hook EB, Cross PK, Schreinemachers DM. Chromosomal abnormality rates at amniocentesis and in live-born infants. JAMA 1983;249:2034-8.
    • (1983) JAMA , vol.249 , pp. 2034-2038
    • Hook, E.B.1    Cross, P.K.2    Schreinemachers, D.M.3
  • 42
    • 0024817810 scopus 로고
    • The natural history of cytogenetically abnormal fetuses detected at midtrimester amniocentesis which are not terminated electively: New data and estimates of the excess and relative risk of later fetal death associated with 47, + 21 and some other abnormal karyotypes
    • Hook EB, Topol BB, Cross PK, The natural history of cytogenetically abnormal fetuses detected at midtrimester amniocentesis which are not terminated electively: new data and estimates of the excess and relative risk of later fetal death associated with 47, + 21 and some other abnormal karyotypes. Am J Hum Genet 1989;45:855-61.
    • (1989) Am J Hum Genet , vol.45 , pp. 855-861
    • Hook, E.B.1    Topol, B.B.2    Cross, P.K.3
  • 43
    • 0029076149 scopus 로고
    • Risk-based screening for trisomy 18 using alpha-fetoprotein, unconjugated estriol, and human chorionic gonadotropin
    • Palomaki GE, Haddow JE, Knight GE, et al. Risk-based screening for trisomy 18 using alpha-fetoprotein, unconjugated estriol, and human chorionic gonadotropin. Prenat Diagn 1995;15:713-23.
    • (1995) Prenat Diagn , vol.15 , pp. 713-723
    • Palomaki, G.E.1    Haddow, J.E.2    Knight, G.E.3
  • 44
    • 0025103971 scopus 로고
    • Prenatal screening for trisomy 18 in the second trimester
    • Canick JA, Palomaki GE, Osathanondh R. Prenatal screening for trisomy 18 in the second trimester, Prenat Diagn 1990;10:546-7.
    • (1990) Prenat Diagn , vol.10 , pp. 546-547
    • Canick, J.A.1    Palomaki, G.E.2    Osathanondh, R.3
  • 45
    • 0036796080 scopus 로고    scopus 로고
    • A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A
    • Spencer K, Nicolaides KH. A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A. Prenat Diagn 2002;22:877-9.
    • (2002) Prenat Diagn , vol.22 , pp. 877-879
    • Spencer, K.1    Nicolaides, K.H.2
  • 46
    • 0026644416 scopus 로고
    • Multiple-marker screening in pregnancies with hydropic and nonhydropic Turner syndrome
    • Saller DN Jr, Canick JA, Schwartz S, et al. Multiple-marker screening in pregnancies with hydropic and nonhydropic Turner syndrome. Am J Obstet Gynecol 1992;167:1021-4.
    • (1992) Am J Obstet Gynecol , vol.167 , pp. 1021-1024
    • Saller D.N., Jr.1    Canick, J.A.2    Schwartz, S.3
  • 47
    • 0031736734 scopus 로고    scopus 로고
    • Second trimester maternal serum and inhibin A levels in fetal trisomy 18 and Turner syndrome with and without hydrops
    • Lambert-Messerlian GM, Saller DN, Tumber MB, et al. Second trimester maternal serum and inhibin A levels in fetal trisomy 18 and Turner syndrome with and without hydrops. Prenat Diagn 1998;18:1061-7.
    • (1998) Prenat Diagn , vol.18 , pp. 1061-1067
    • Lambert-Messerlian, G.M.1    Saller, D.N.2    Tumber, M.B.3
  • 48
    • 0034855250 scopus 로고    scopus 로고
    • Second trimester maternal serum analytes in triploid pregnancies: Correlation with phenotype and sex chromosome complement
    • Benn PA, Gainey A, Ingardia CJ, et al. Second trimester maternal serum analytes in triploid pregnancies: correlation with phenotype and sex chromosome complement. Prenat Diagn 2001;21:680-6.
    • (2001) Prenat Diagn , vol.21 , pp. 680-686
    • Benn, P.A.1    Gainey, A.2    Ingardia, C.J.3
  • 49
    • 0026750518 scopus 로고
    • Maternal serum hCG levels in triploidy: Variability and need to consider molar tissue
    • Oyer CE, Canick JA. Maternal serum hCG levels in triploidy: variability and need to consider molar tissue. Prenat Diagn 1992;12:627-9.
    • (1992) Prenat Diagn , vol.12 , pp. 627-629
    • Oyer, C.E.1    Canick, J.A.2
  • 50
    • 0345035259 scopus 로고    scopus 로고
    • Second-trimester maternal serum analyte levels associated with fetal trisomy 13
    • Saller DN Jr, Canick JA, Blitzer MG, et al. Second-trimester maternal serum analyte levels associated with fetal trisomy 13. Prenat Diagn 1999;19:813-6.
    • (1999) Prenat Diagn , vol.19 , pp. 813-816
    • Saller D.N., Jr.1    Canick, J.A.2    Blitzer, M.G.3
  • 51
    • 0032710295 scopus 로고    scopus 로고
    • Screening for trisomy 18 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation
    • Spencer K, Noble P, Chan C, Nicolaides K. Screening for trisomy 18 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation. Prenat Diagn 1999;19:1035-42.
    • (1999) Prenat Diagn , vol.19 , pp. 1035-1042
    • Spencer, K.1    Noble, P.2    Chan, C.3    Nicolaides, K.4
  • 52
    • 0034073499 scopus 로고    scopus 로고
    • Screening for trisomy 13 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation
    • Spencer K, Ong C, Skentou, Liao AW, Nicolaides KH. Screening for trisomy 13 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation. Prenat Diagn 2000;20:411-6.
    • (2000) Prenat Diagn , vol.20 , pp. 411-416
    • Spencer, K.1    Ong, C.2    Skentou3    Liao, A.W.4    Nicolaides, K.H.5
  • 53
    • 0034041082 scopus 로고    scopus 로고
    • Screening for triploidy by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation
    • Spencer K, Liao AW, Skentou H, Cicero S, Nicolaides KH. Screening for triploidy by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation, Prenat Diagn 2000;20:495-9.
    • (2000) Prenat Diagn , vol.20 , pp. 495-499
    • Spencer, K.1    Liao, A.W.2    Skentou, H.3    Cicero, S.4    Nicolaides, K.H.5
  • 54
    • 0000727177 scopus 로고
    • Defective cholesterol biosynthesis associated with the Smith Lemli Opitz syndrome
    • Tint GS, Irons M, Elias ER, et al. Defective cholesterol biosynthesis associated with the Smith Lemli Opitz syndrome. N Engl J Med 1994;30:107-13.
    • (1994) N Engl J Med , vol.30 , pp. 107-113
    • Tint, G.S.1    Irons, M.2    Elias, E.R.3
  • 55
    • 0033590680 scopus 로고    scopus 로고
    • Levels of unconjugated estriol and other maternal serum markers in pregnancies with Smith-Lemli-Opitz (SLO) syndrome fetuses
    • Bradley LA, Palomaki GE, Knight GJ, et al. Levels of unconjugated estriol and other maternal serum markers in pregnancies with Smith-Lemli-Opitz (SLO) syndrome fetuses. Am J Med Genet 1999;82:355-8.
    • (1999) Am J Med Genet , vol.82 , pp. 355-358
    • Bradley, L.A.1    Palomaki, G.E.2    Knight, G.J.3
  • 56
    • 0036227784 scopus 로고    scopus 로고
    • Assigning risk for Smith-Lemli-Opitz syndrome as part of 2nd trimester screening for Down's syndrome
    • Palomaki GE, Bradley LA, Knight GJ, Craig WY, Haddow JE. Assigning risk for Smith-Lemli-Opitz syndrome as part of 2nd trimester screening for Down's syndrome. J Med Screen 2002;9:43-4.
    • (2002) J Med Screen , vol.9 , pp. 43-44
    • Palomaki, G.E.1    Bradley, L.A.2    Knight, G.J.3    Craig, W.Y.4    Haddow, J.E.5
  • 57
    • 70449245071 scopus 로고
    • Etude des chromosomes somatiques de neuf enfants mongoliens
    • Lejeune J, Gautier M, Turpin R. Etude des chromosomes somatiques de neuf enfants mongoliens. CR Acad Sci Paris 1959;248:1721-2.
    • (1959) CR Acad Sci Paris , vol.248 , pp. 1721-1722
    • Lejeune, J.1    Gautier, M.2    Turpin, R.3
  • 58
    • 85045797401 scopus 로고    scopus 로고
    • First and second trimester antenatal screening for Down's syndrome: Results of the Serum, Urine and Ultrasound Screening Study (SURUSS)
    • Wald NJ, Rodeck C, Hackshaw AK, Walters J, Chitty L, Mackinson AM. First and second trimester antenatal screening for Down's syndrome: results of the Serum, Urine and Ultrasound Screening Study (SURUSS). Health Technol Assess 2003;7(11).
    • (2003) Health Technol Assess , vol.7 , Issue.11
    • Wald, N.J.1    Rodeck, C.2    Hackshaw, A.K.3    Walters, J.4    Chitty, L.5    Mackinson, A.M.6
  • 59
    • 0035904786 scopus 로고    scopus 로고
    • Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: An observational study
    • Cicero S, Curcio P, Papageorghiou A, Sonek J, Nicolaides K. Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study. Lancet 2001;358:1665-7.
    • (2001) Lancet , vol.358 , pp. 1665-1667
    • Cicero, S.1    Curcio, P.2    Papageorghiou, A.3    Sonek, J.4    Nicolaides, K.5


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