메뉴 건너뛰기




Volumn 9, Issue SUPPL. 1, 2003, Pages 94-100

Pharmacokinetics of factor VIII and factor IX

Author keywords

Factor IX; Factor VIII; Haemophilia; Pharmacokinetics

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 CONCENTRATE; BLOOD CLOTTING FACTOR 9 COMPLEX; BLOOD CLOTTING FACTOR 9 CONCENTRATE; CHROMOGENIC SUBSTRATE; PRECONATIVE HT; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9; RIBOSOME DNA;

EID: 0037764676     PISSN: 13518216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2516.9.s1.8.x     Document Type: Article
Times cited : (38)

References (40)
  • 1
    • 0021246317 scopus 로고
    • Calculations of factor VIII in vivo recovery and half life
    • Kjellman H. Calculations of factor VIII in vivo recovery and half life. Scand J Haematol 1984; 33 (Suppl. 40): 165-84.
    • (1984) Scand. J. Haematol. , vol.33 , Issue.SUPPL. 40 , pp. 165-184
    • Kjellman, H.1
  • 2
    • 0020806564 scopus 로고
    • Pharmacokinetics of factor VIII. C. Appropriateness of the one-compartment model for estimating clearance
    • Matucci M, Longo G, Morfini M et al. Pharmacokinetics of factor VIII. C. Appropriateness of the one-compartment model for estimating clearance. Il Farmaco 1983; 38: 306-11.
    • (1983) Il Farmaco , vol.38 , pp. 306-311
    • Matucci, M.1    Longo, G.2    Morfini, M.3
  • 3
    • 0021970348 scopus 로고
    • Kinetic evaluation of four factor VIII concentrates by model-independent methods
    • Matucci M, Messori A, Donati-Cori G et al. Kinetic evaluation of four factor VIII concentrates by model-independent methods. Scand J Haematol 1985; 34: 22-8.
    • (1985) Scand. J. Haematol. , vol.34 , pp. 22-28
    • Matucci, M.1    Messori, A.2    Donati-Cori, G.3
  • 4
    • 0022885644 scopus 로고
    • Pharmacokinetics of a new heat-treated concentrate of factor VIII estimated by model-independent methods
    • Longo G, Matucci M, Messori A, Morfini M, Rossi-Ferrini P. Pharmacokinetics of a new heat-treated concentrate of factor VIII estimated by model-independent methods. Thromb Res 1986; 42: 471-6.
    • (1986) Thromb. Res. , vol.42 , pp. 471-476
    • Longo, G.1    Matucci, M.2    Messori, A.3    Morfini, M.4    Rossi-Ferrini, P.5
  • 5
    • 0022407897 scopus 로고
    • Comparison of two pharmacokinetic techniques for individualizing factor VIII dosage in haemophilia patients
    • Morfini M, Grasela TH, Longo G et al. Comparison of two pharmacokinetic techniques for individualizing factor VIII dosage in haemophilia patients. Haematologica 1985; 70: 454-6.
    • (1985) Haematologica , vol.70 , pp. 454-456
    • Morfini, M.1    Grasela, T.H.2    Longo, G.3
  • 7
    • 0024273204 scopus 로고
    • Multi-variate analysis of factors governing the pharmacokinetics of exogenous factor VIII in haemophiliacs
    • Messori A, Longo G, Morfini M et al. Multi-variate analysis of factors governing the pharmacokinetics of exogenous factor VIII in haemophiliacs. Eur J Clin Pharmacol 1988; 35: 663-8.
    • (1988) Eur. J. Clin. Pharmacol. , vol.35 , pp. 663-668
    • Messori, A.1    Longo, G.2    Morfini, M.3
  • 8
    • 0026609355 scopus 로고
    • Pharmacokinetics of factor VIII in humans. Obtaining clinically relevant data from comparative studies
    • Bjorkman S, Carlsson M, Berntorp E, Stenberg P. Pharmacokinetics of factor VIII in humans. Obtaining clinically relevant data from comparative studies. Clin Pharmacokinet 1992; 22: 385-95.
    • (1992) Clin. Pharmacokinet. , vol.22 , pp. 385-395
    • Bjorkman, S.1    Carlsson, M.2    Berntorp, E.3    Stenberg, P.4
  • 10
    • 0028365342 scopus 로고
    • Pharmacokinetics of factor IX in patients with haemophilia B. Methodological aspects and physiological interpretation
    • Bjorkman S, Carlsson M, Berntorp E. Pharmacokinetics of factor IX in patients with haemophilia B. Methodological aspects and physiological interpretation. Eur J Clin Pharmacol 1994; 46: 325-32.
    • (1994) Eur. J. Clin. Pharmacol. , vol.46 , pp. 325-332
    • Bjorkman, S.1    Carlsson, M.2    Berntorp, E.3
  • 11
    • 0025847974 scopus 로고
    • The design and analysis of half-life and recovery studies for factor VIII and factor IX
    • Morfini M, Lee M, Messori A. The design and analysis of half-life and recovery studies for factor VIII and factor IX. Thromb Haemost 1991; 66: 384-6.
    • (1991) Thromb. Haemost. , vol.66 , pp. 384-386
    • Morfini, M.1    Lee, M.2    Messori, A.3
  • 12
    • 27744581791 scopus 로고    scopus 로고
    • The design and analysis of pharmacokinetic studies of coagulation factors
    • Factor VIII/IX SSC-ISTH recommendations at
    • Lee M, Morfini M, Schulman S, Ingerslev J. The design and analysis of pharmacokinetic studies of coagulation factors. Factor VIII/IX SSC-ISTH recommendations at http://www.med.unc.edu/isth/fviiipharmaco.htm.
    • Lee, M.1    Morfini, M.2    Schulman, S.3    Ingerslev, J.4
  • 13
    • 13844295682 scopus 로고    scopus 로고
    • Guidance on the Clinical Investigation of Human Plasma Derived Factor VIII and IX Products
    • Committee for Proprietary Medicinal Products. London: CPMP, 19 October
    • Committee for Proprietary Medicinal Products. Guidance on the Clinical Investigation of Human Plasma Derived Factor VIII and IX Products. London: CPMP, 19 October 2000.
    • (2000)
  • 14
    • 0026882719 scopus 로고
    • A pharmacokinetic program for least-squares and Bayesian analysis of repeated-dose pharmacokinetic curves
    • Messori A, Bosi A, Guidi S et al. A pharmacokinetic program for least-squares and Bayesian analysis of repeated-dose pharmacokinetic curves. Comp Meth Progr Biomed 1992; 38: 27-35.
    • (1992) Comp. Meth. Progr. Biomed. , vol.38 , pp. 27-35
    • Messori, A.1    Bosi, A.2    Guidi, S.3
  • 15
    • 0017570239 scopus 로고
    • Characteristics of various factor VIII concentrates used in treatment of haemophilia A
    • Nilsson IM, Hedner U. Characteristics of various factor VIII concentrates used in treatment of haemophilia A. Br J Haematol 1977; 37: 543-57.
    • (1977) Br. J. Haematol. , vol.37 , pp. 543-557
    • Nilsson, I.M.1    Hedner, U.2
  • 16
    • 0028894930 scopus 로고
    • In vivo recovery of factor VIII following transfusion: A survey of recent data and publications to assess the influence of standards uses for potency assignment
    • Prowse CV. In vivo recovery of factor VIII following transfusion: a survey of recent data and publications to assess the influence of standards uses for potency assignment. Thromb Haemost 1995; 74: 1191-6.
    • (1995) Thromb. Haemost. , vol.74 , pp. 1191-1196
    • Prowse, C.V.1
  • 17
    • 0026736639 scopus 로고
    • Pharmacokinetics of two pasteurized factor VIII concentrates by different and multicentre assays of factor VIII activity
    • Messori A, Morfini M, Blomback M et al. Pharmacokinetics of two pasteurized factor VIII concentrates by different and multicentre assays of factor VIII activity. Thromb Res 1992; 65: 699-708.
    • (1992) Thromb. Res. , vol.65 , pp. 699-708
    • Messori, A.1    Morfini, M.2    Blomback, M.3
  • 18
    • 0025644310 scopus 로고
    • Human recombinant DNA-derived antihemophilic factor (factor VIII) in the treatment of haemophilia A
    • Recombinant Factor VIII Study Group
    • Schwartz RS, Abildgaard CF, Aledort LM et al. Human recombinant DNA-derived antihemophilic factor (factor VIII) in the treatment of haemophilia A. Recombinant Factor VIII Study Group. N Engl J Med 1990; 323: 1800-5.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1800-1805
    • Schwartz, R.S.1    Abildgaard, C.F.2    Aledort, L.M.3
  • 19
    • 0030942094 scopus 로고    scopus 로고
    • A multicenter study of recombinant factor VIII (Recombinate) in previously treated patients with hemophilia A
    • The Recombinate Previously Treated Patient Study Group
    • White GC, Courter S, Bray GL, Lee M, Gomperts ED. A multicenter study of recombinant factor VIII (Recombinate) in previously treated patients with hemophilia A. The Recombinate Previously Treated Patient Study Group. Thromb Haemost 1997; 77: 660-7.
    • (1997) Thromb. Haemost. , vol.77 , pp. 660-667
    • White, G.C.1    Courter, S.2    Bray, G.L.3    Lee, M.4    Gomperts, E.D.5
  • 20
    • 0031059825 scopus 로고    scopus 로고
    • Recombinant, b-domain deleted Factor VIII (r-VIII SQ): Pharmacokinetics and initial safety aspects in hemophilia A patients
    • Fijnvandraat K, Berntorp E, ten Cate JW et al. Recombinant, b-domain deleted Factor VIII (r-VIII SQ): Pharmacokinetics and initial safety aspects in hemophilia A patients. Thromb Haemost 1997; 77: 298-302.
    • (1997) Thromb. Haemost. , vol.77 , pp. 298-302
    • Fijnvandraat, K.1    Berntorp, E.2    ten Cate, J.W.3
  • 21
    • 0028907225 scopus 로고
    • Comparison of the recovery and half-life of a high-purity factor IX concentrate with those of a factor IX complex concentrate
    • Factor IX Study Group
    • Poon MC, Aledort LM, Anderle K, Kunschak M, Morfini M. Comparison of the recovery and half-life of a high-purity factor IX concentrate with those of a factor IX complex concentrate. Factor IX Study Group. Transfusion 1995; 35: 319-23.
    • (1995) Transfusion , vol.35 , pp. 319-323
    • Poon, M.C.1    Aledort, L.M.2    Anderle, K.3    Kunschak, M.4    Morfini, M.5
  • 22
    • 0027326445 scopus 로고
    • Pharmacokinetics, thrombogenicity and safety of a double-treated prothrombin complex concentrate
    • Messori A, Nilsson IM, Rossi Ferrini P. Pharmacokinetics, thrombogenicity and safety of a double-treated prothrombin complex concentrate. Thromb Res 1993; 71: 175-84.
    • (1993) Thromb. Res. , vol.71 , pp. 175-184
    • Messori, A.1    Nilsson, I.M.2    Rossi Ferrini, P.3
  • 24
    • 0025822381 scopus 로고
    • Comparative evaluation of the pharmacokinetics of three monoclonal factor VIII concentrates
    • Morfini M, Mannucci PM, Longo G, Cinotti S, Messori A. Comparative evaluation of the pharmacokinetics of three monoclonal factor VIII concentrates. Thromb Res 1991; 61: 285-90.
    • (1991) Thromb. Res. , vol.61 , pp. 285-290
    • Morfini, M.1    Mannucci, P.M.2    Longo, G.3    Cinotti, S.4    Messori, A.5
  • 25
    • 0037649416 scopus 로고    scopus 로고
    • Single dose pharmacokinetic evaluation of ReFacto, B-domain-deleted recombinant factor VIII, using one-stage and chromogenic assays: Comparison between plasma and concentrate laboratory standards
    • Abstract at the 42nd Annual Meeting of the ASH, December 1-5, 2000: San Francisco, CA
    • Morfini M, Cinotti S, Paladino E, Mannucci PM, Bellatreccia A, Bianchi C. Single dose pharmacokinetic evaluation of ReFacto, B-domain-deleted recombinant factor VIII, using one-stage and chromogenic assays: comparison between plasma and concentrate laboratory standards. Abstract at the 42nd Annual Meeting of the ASH, December 1-5, 2000: San Francisco, CA. Blood 2000; 96: 490.
    • (2000) Blood , vol.96 , pp. 490
    • Morfini, M.1    Cinotti, S.2    Paladino, E.3    Mannucci, P.M.4    Bellatreccia, A.5    Bianchi, C.6
  • 26
    • 0024549302 scopus 로고
    • Evaluation of factor VIII pharmacokinetics in hemophilia A subjects undergoing surgery and description of a nomogram for dosing calculations
    • Longo G, Messori A, Morfini M et al. Evaluation of factor VIII pharmacokinetics in hemophilia A subjects undergoing surgery and description of a nomogram for dosing calculations. Am J Hematol 1989; 30: 140-9.
    • (1989) Am. J. Hematol. , vol.30 , pp. 140-149
    • Longo, G.1    Messori, A.2    Morfini, M.3
  • 29
    • 0021978511 scopus 로고
    • A calculator program for clinical application of the Bayesian method of predicting plasma drug levels
    • Ruffo S, Messori A, Grasela TH et al. A calculator program for clinical application of the Bayesian method of predicting plasma drug levels. Comput Programs Biomed 1985; 19: 167-77.
    • (1985) Comput. Programs Biomed. , vol.19 , pp. 167-177
    • Ruffo, S.1    Messori, A.2    Grasela, T.H.3
  • 30
    • 0018075263 scopus 로고
    • Discrepancies between one-stage and two-stage assay of Factor VIII. C
    • Kirkwood TBL, Barrowcliffe TW. Discrepancies between one-stage and two-stage assay of Factor VIII. C. Br J Haematol 1978; 40: 333-8.
    • (1978) Br. J. Haematol. , vol.40 , pp. 333-338
    • Kirkwood, T.B.L.1    Barrowcliffe, T.W.2
  • 32
    • 0027208124 scopus 로고
    • The behaviour of different factor VIII concentrates in a chromogenic factor X-activating system
    • Kemball-Cook G, Tubbs JE, Dawson NJ, Barrowcliffe TW. The behaviour of different factor VIII concentrates in a chromogenic factor X-activating system. Br J Haematol 1993; 84: 273-8.
    • (1993) Br. J. Haematol. , vol.84 , pp. 273-278
    • Kemball-Cook, G.1    Tubbs, J.E.2    Dawson, N.J.3    Barrowcliffe, T.W.4
  • 33
    • 0014504587 scopus 로고
    • Activated coagulation factors. In vivo and in-vitro studies
    • Niemetz J, Nossel HL. Activated coagulation factors. In vivo and in-vitro studies. Br J Haematol 1969; 16: 337-51.
    • (1969) Br. J. Haematol. , vol.16 , pp. 337-351
    • Niemetz, J.1    Nossel, H.L.2
  • 34
    • 0028332388 scopus 로고
    • Potency and in vivo recovery of high purity factor VIII concentrates
    • Mikaelsson M, Oswaldsson U, Nilsson IM. Potency and in vivo recovery of high purity factor VIII concentrates. Thromb Haemost 1994; 72: 160-1.
    • (1994) Thromb. Haemost. , vol.72 , pp. 160-161
    • Mikaelsson, M.1    Oswaldsson, U.2    Nilsson, I.M.3
  • 36
    • 0031828437 scopus 로고    scopus 로고
    • Discrepancies in potency assessment of recombinant FVIII concentrates
    • Barrowcliffe TW, Raut S, Hubbard R. Discrepancies in potency assessment of recombinant FVIII concentrates. Haemophilia 1998; 4: 634-40.
    • (1998) Haemophilia , vol.4 , pp. 634-640
    • Barrowcliffe, T.W.1    Raut, S.2    Hubbard, R.3
  • 37
    • 0031878077 scopus 로고    scopus 로고
    • Influence of phospholipids on the assessment of factor VIII activity
    • Mikaelsson M, Oswaldsson U, Sandberg H. Influence of phospholipids on the assessment of factor VIII activity. Haemophilia 1998; 4: 646-50.
    • (1998) Haemophilia , vol.4 , pp. 646-650
    • Mikaelsson, M.1    Oswaldsson, U.2    Sandberg, H.3
  • 38
    • 0032751069 scopus 로고    scopus 로고
    • Pharmacokinetics of recombinant factor VIIII (Recombinate) using one-stage clotting and chromogenic factor VIII assay
    • Lee C, Owens D, Bray G et al. Pharmacokinetics of recombinant factor VIIII (Recombinate) using one-stage clotting and chromogenic factor VIII assay. Thromb Haemost 1999; 82: 1644-7.
    • (1999) Thromb. Haemost. , vol.82 , pp. 1644-1647
    • Lee, C.1    Owens, D.2    Bray, G.3
  • 39
    • 0031857499 scopus 로고    scopus 로고
    • In vivo recovery with products of very high purity-assay discrepancies
    • Lusher JM, Hillman-Wiseman C, Hurst D. In vivo recovery with products of very high purity-assay discrepancies. Haemophilia 1998; 4: 641-5.
    • (1998) Haemophilia , vol.4 , pp. 641-645
    • Lusher, J.M.1    Hillman-Wiseman, C.2    Hurst, D.3
  • 40
    • 0037987194 scopus 로고    scopus 로고
    • Results of a collaborative Nordic field Study (RASPUTIN) on determination of recombinant B-domain deleted Factor VIII in Plasma employing a (Refacto) concentrate standard
    • and the Nordic ReFacto Study Group. Abstract P2576 at XVIII Congress of ISTH, July 6-12, 2001: Paris. July
    • Ingerslev J, Oswaldsson U, Renlund S, Mikaelsson M and the Nordic ReFacto Study Group. Results of a collaborative Nordic field Study (RASPUTIN) on determination of recombinant B-domain deleted Factor VIII in Plasma employing a (Refacto) concentrate standard. Abstract P2576 at XVIII Congress of ISTH, July 6-12, 2001: Paris. Thromb Haemost (Suppl.) July 2001.
    • (2001) Thromb. Haemost. , Issue.SUPPL.
    • Ingerslev, J.1    Oswaldsson, U.2    Renlund, S.3    Mikaelsson, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.