Pharmacokinetics of a nicotine polacrilex lozenge

Nicotine and Tobacco Research

Volumn 5, Issue 5, 2003, Pages 635-644

  Choi, Jae H ^a   Dresler, Carolyn M ^a   Norton, Michele R ^a   Strahs, Kenneth R ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CYCLODEXTRIN NICOTINE; NICORETTE GUM; NICORETTE MICROTAB; NICOTINE; NICOTINE DERIVATIVE; NICOTINE GUM; NICOTINE TARTRATE; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG LABELING; DRUG SAFETY; HEADACHE; HUMAN; LOZENGE; MASTICATION; NAUSEA; NORMAL HUMAN; PALLOR; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SMOKING; SMOKING CESSATION; SWALLOWING; SWEAT GLAND DISEASE; TACHYCARDIA; VERTIGO;

ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; CENTRAL NERVOUS SYSTEM STIMULANTS; CHEWING GUM; CROSS-OVER STUDIES; FEMALE; HUMANS; ION EXCHANGE RESINS; MALE; NICOTINE; POLYMETHACRYLIC ACIDS; POLYVINYLS; SMOKING CESSATION; TOBACCO USE DISORDER;

EID: 0037760692     PISSN: 14622203     EISSN: None     Source Type: Journal    
DOI: 10.1080/1462220031000158690     Document Type: Article

References (6)

1. Benowitz, N. L., Jacob, P. III, & Savanapridi, C. (1987). Determinants of nicotine intake while chewing nicotine polacrilex gum Clinical Pharmacology and Therapeutics, 41, 467-473.
2. Fiore, M. C., Bailey, W. C., Cohen, S. J., Dorfman, S. F., Goldstein, M. G., & Gritz, E. R., et al. (2000). Clinical practice guideline: Treating tobacco use and dependence. Rockville, MD: U.S. Department of Health and Human Services, Public Health Service.
3. Molander, L., & Lunell, E. (2001). Pharmacokinetic investigation of a nicotine sublingual tablet European Journal of Clinical Pharmacology, 56, 813-819.
4. Nemeth-Coslett, R., Benowitz, N. L., Robinson, N., & Henningfield, J. E. (1988). Nicotine gum: Chew rate, subjective effects and plasma nicotine Pharmacology Biochemistry and Behavior, 29, 747-751.
5. Shiffman, S., Dresler, C. M., Hajek, P., Gilburt, S. J. A., Targett, D. A., & Strahs, K. R (2002). Efficacy of a nicotine lozenge for smoking cessation Archives of Internal Medicine, 162, 1267-1276.
6. World Medical Association. (1996). Declaration of Helsinki. 48th World Medical Assembly. Somerset West, Republic of South Africa. Accessed April 21, 2003, from http://www.wma.net/e/policy/17-c_e.html.