Full-thickness human foreskin transplantation onto nude rats as an in vivo model of acute human wound healing

Plastic and Reconstructive Surgery

Volumn 111, Issue 6, 2003, Pages 1988-1997

  Petratos, Peter B ^b   Chen, Jie ^b   Soslow, Robert A ^b   Bleustein, Clifford B ^b   Felsen, Diane ^b   Poppas, Dix P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASEMENT MEMBRANE; CIRCUMCISION; CONTROLLED STUDY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GRANULATION TISSUE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; NONHUMAN; NUDE MOUSE; PREPUCE; PRIORITY JOURNAL; RAT; SKIN TRANSPLANTATION; SPLIT THICKNESS SKIN GRAFT; WOUND HEALING; XENOGRAFT; ANIMAL; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; INJURY; MALE; METABOLISM; NUDE RAT; PATHOLOGY; PENIS; PHYSIOLOGY; SKIN;

BLOOD CLOTTING FACTOR 8; CYCLINE;

ANIMALS; FACTOR VIII; GRAFT SURVIVAL; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MODELS, ANIMAL; PENIS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, NUDE; SKIN; SKIN TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS; WOUND HEALING;

EID: 0037739661     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000056831.87062.4B     Document Type: Article

References (24)

1. Singer, A. J., and Clark, R. A. F. Cutaneous wound healing. N. Engl. J. Med. 341: 738, 1999.
2. Manning, D. D., Reed, N. D., and Shaffer, C. F. Maintenance of skin xenografts of widely divergent phylogenetic origin of congenitally athymic (nude) mice. J. Exp. Med. 138: 488, 1973.
3. Rygaard, J. Skin grafts in nude mice: 3. Fate of grafts from man and donors of other taxonomic classes. Acta Pathol. Microbiol. Scand. [A] 82: 105, 1974.
4. Demarchez, M., Sengel, P., and Prunieras, M. Wound healing of human skin transplanted onto the nude mouse: I. An immunohistological study of the reepithelialization process. Dev. Biol. 113: 90, 1986.
5. Demarchez, M., Hartmann, D. J., Herbage, D., Ville, G., and Prunieras, M. Wound healing of human skin transplanted onto the nude mouse: II. An immunological study and ultrastructural study of the epidermal basement membrane zone reconstruction and connective tissue reorganization. Dev. Biol. 121: 119, 1987.
6. Demarchez, M., Hartman, D. J., and Prunieras, M. An immunohistological study of the revascularization process in human skin transplanted onto the nude mouse. Transplantation 43: 896, 1987.
7. Gilhar, A., Wojciechowski, Z. J., Piepkorn, M. W., Spangrude, G. J., Roberts, L. K., and Krueger, G. G. Description of and treatment to inhibit the rejection of human split-thickness skin grafts by congenitally athymic (nude) rats. Exp. Cell Biol. 54: 263, 1986.
8. Wojciechowski, Z., Pershing, L. K., Huether, S., et al. An experimental skin sandwich flap on an independent vascular supply for the study of percutaneous adsorption. J. Invest. Dermatol. 88: 439, 1987.
9. Briggaman, R. A. Localisation of the defect in skin diseases analyzed in the human skin graft-nude mouse model. Curr. Probl. Dermatol. 10: 115, 1980.
10. Vos, J. G., Kreeftenberg, J. G., Kruijt, B. C., Kruizinga, W., and Steerenberg, P. The athymic nude rat: II. Immunological characteristics. Clin. Immunol. Immunopathol. 15: 229, 1980.
11. Brungger, A., Hubler, M., and Rohr, H. P. Human skin grafts on athymic nude rats: An experimental model for dermatological research. Exp. Cell Biol. 52: 122, 1984.
12. Polo, M., Kim, Y-J., Kucukcelebi, A., Hayward, P. G., Ko, F., and Robson, M. C. An in vivo model of human proliferative scar. J. Surg. Res. 74: 187, 1998.
13. Wang, X., Smith, P., Pu, L. L. Q., Kim, Y. J., Ko, F., and Robson, M. C. Exogenous transforming growth factor β2 modulates collagen I and collagen III synthesis in proliferative scar xenografts in nude rats. J. Surg. Res. 87: 194, 1999.
14. Bleustein, C. B., Walker, C. N., Felsen, D., and Poppas, D. P. Semi-solid albumin solder improved mechanical properties for laser tissue welding. Lasers Surg. Med. 27: 140, 2000.
15. Miyajima, A., Chen, J., Lawrence, C., et al. Antibody to transforming growth factor-β ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int. 58: 2301, 2000.
16. Weidner, N., Semple, J. P., Welch, W. R., and Folkman, J. Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma. N. Engl. J. Med. 324: 1, 1991.
17. Massicotte, J. M., Stewart, R. B., and Poppas, D. P. Effects of endogenous absorption in human albumin solder for acute laser wound closure. Lasers Surg. Med. 23: 18, 1998.
18. Lorenz, H. P., Longaker, M. T., Perkocha, L. A., Jennings, R. W., Harrison, M. R., and Adzick, N. S. Scarless wound repair: A human fetal skin model. Development 114: 253, 1992.
19. Jelaska, A., and Korn, J. H. Anti-Fas induces apoptosis and proliferation in human dermal fibroblasts: Differences between foreskin and adult fibroblasts. J. Cell Physiol. 175: 19, 1998.
20. Harries, R. H., Rogers, B. G., Leitch, I. O., and Robson, M. C. An in vivo model for epithelialization kinetics in human skin. Aust. N. Z. J. Surg. 65: 600, 1995.
21. Jimenez, P. A., and Rampy, M. A. Keritinocyte growth factor-2 accelerates wound healing in incisional wounds. J. Surg. Res. 81: 238, 1999.
22. Berger, A. C., Feldman, A. L., Gnant, M. F., et al. The angiogenesis inhibitor, endostatin, does not affect murine cutaneous wound healing. J. Surg. Res. 91: 26, 2000.
23. Odland, G., and Ross, R. Human wound repair: I. Epidermal regeneration. J. Cell Biol. 39: 135, 1968.
24. Ross, R., and Odland, G. Human wound repair: II. Inflammatory cells, epithelial-mesenchymal interrelations, and fibrogenesis. J. Cell Biol. 39: 152, 1968.