Engineering of A3 adenosine and P2Y nucleotide receptors and their ligands

Drug Development Research

Volumn 58, Issue 4, 2003, Pages 330-339

  Jacobson, Kenneth A ^a   Kim, Hak Sung ^a   Ravi, Gnana ^a   Kim, Soo Kyung ^a   Lee, Kyeong ^a   Chen, Aishe ^a   Chen, Wangzhong ^a   Kim, Seong Gon ^a   Barak, Dov ^a,b   Liang, Bruce T ^c   Gao, Zhan Guo ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

ARs; G protein coupled receptors; Nucleosides; Nucleotides; Purines; Structure activity relationships

Indexed keywords

2 CHLORO 6 N (3 IODOBENZYL) 5' N METHYLCARBAMOYLADENOSINE; 6 N CYCLOPENTYLADENOSINE; 9 CHLORO 2 (2 FURYL) 5 PHENYLACETYLAMINO 1,2,4 TRIAZOLO[1,5 C]QUINAZOLINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE DIPHOSPHATE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; BICYCLO COMPOUND; G PROTEIN COUPLED RECEPTOR; LIGAND; MRS 1740; MRS 1741; MRS 1743; MRS 1760; MRS 1898; MRS 2297; MRS 2298; MRS 2340; MRS 2341; MRS 2365; NUCLEOSIDE; NUCLEOTIDE; PURINE DERIVATIVE; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; RECEPTOR SUBTYPE; RHODOPSIN; RIBOSE; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; CELL STRAIN HL 60; CHO CELL; CONFERENCE PAPER; CONFORMATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; GENE TRANSFER; GENETIC ENGINEERING; HEART PROTECTION; HUMAN; HUMAN CELL; NONHUMAN; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0037712870     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10168     Document Type: Conference Paper

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