Apolipoprotein A-II: Active or passive role in familial combined hyperlipidemia

Circulation Research

Volumn 92, Issue 11, 2003, Pages 1179-1181

  Aouizerat, Bradley E ^a   Kane, John P ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apolipoprotein A II; Familial combined hyperlipidemia; High density lipoproteins; Hypertriglyceridemia; Triglycerides

Indexed keywords

APOLIPOPROTEIN A2; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN; TRIACYLGLYCEROL;

ATHEROGENESIS; CHOLESTEROL TRANSPORT; EDITORIAL; FAMILIAL HYPERLIPEMIA; GENETIC LINKAGE; HUMAN; HYPERTRIGLYCERIDEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; ANIMAL; BLOOD; GENETIC PREDISPOSITION; GENETICS; METABOLIC SYNDROME X; MOUSE; NOTE; PHYSIOLOGY;

ANIMALS; APOLIPOPROTEIN A-II; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERLIPIDEMIA, FAMILIAL COMBINED; LIPOPROTEINS; LIPOPROTEINS, HDL; METABOLIC SYNDROME X; MICE; TRIGLYCERIDES;

EID: 0037704220     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000078362.26826.40     Document Type: Editorial

References (20)

1. Nikkila EA, Aro A. Family study of serum lipids and lipoproteins in coronary heart-disease. Lancet. 1973;1:954-959.
2. Rose HG, Kranz P, Weinstock M, Juliano J, Haft JI. Inheritance of combined hyperlipoproteinemia: evidence for a new lipoprotein phenotype. Am J Med. 1973;54:148-160.
3. Goldstein JL, Schrott HG, Hazzard WR, Bierman EL, Motulsky AG. Hyperlipidemia in coronary heart disease, II: genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J Clin Invest. 1973;52:1544-1568.
4. Kane JP, Havel RJ. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In: Scriver CR, Sly WS, Childs B, Beaudet AL, Valle D, Kinzler KW, Vogelstein B, eds. The Metabolic and Molecular Bases of Inherited Disease. 8th ed. New York, NY: McGraw-Hill/Medical Publishing Division; 2001:2717-2752.
5. Williams RR, Hopkins PN, Hunt SC, Schumacher MC, Elbein SC, Wilson DE, Stults BM, Wu LL, Hasstedt SJ, Lalouel JM. Familial dyslipidaemic hypertension and other multiple metabolic syndromes. Ann Med. 1992;24:469-475.
6. Castro Cabezas M, de Bruin TW, de Valk HW, Shoulders CC, Jansen H, Erkelens DW. Impaired fatty acid metabolism in familial combined hyperlipidemia: a mechanism associating hepatic apolipoprotein B overproduction and insulin resistance. J Clin Invest. 1993;92:160-168.
7. Demacker PN, Veerkamp MJ, Bredie SJ, Marcovina SM, de Graaf J, Stalenhoef AF. Comparison of the measurement of lipids and lipoproteins versus assay of apolipoprotein B for estimation of coronary heart disease risk: a study in familial combined hyperlipidemia. Atherosclerosis. 2000;153:483-490.
8. Allayee H, Castellani LW, Cantor RM, de Bruin TWA, Lusis AJ. Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia. Circ Res. 2003;92:1262-1267.
9. Castellani LW, Navab M, Van Lenten BJ, Hedrick CC, Hama SY, Goto AM, Fogelman AM, Lusis AJ. Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. J Clin Invest. 1997;100:464-474.
10. Boisfer E, Stengel D, Pastier D, Laplaud PM, Dousset N, Ninio E, Kalopissis AD. Antioxidant properties of HDL in transgenic mice overexpressing human apolipoprotein A-II. J Lipid Res. 2002;43:732-741.
11. Allayee H, Dominguez KM, Aouizerat BE, Krauss RM, Rotter JI, Lu J, Cantor RM, de Bruin TW, Lusis AJ. Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J Lipid Res. 2000;41:245-252.
12. Rainwater DL, Mitchell BD, Mahaney MC, Haffner SM. Genetic relationship between measures of HDL phenotypes and insulin concentrations. Arterioscler Thromb Vasc Biol. 1997;17:3414-3419.
13. Colhoun HM, Taskinen MR, Otvos JD, Van Den Berg P, O'Connor J, Van Tol A. Relationship of phospholipid transfer protein activity to HDL and apolipoprotein B-containing lipoproteins in subjects with and without type 1 diabetes. Diabetes. 2002;51:3300-3305.
14. Bouly M, Masson D, Gross B, Jiang XC, Fievet C, Castro G, Tall AR, Fruchart JC, Staels B, Lagrost L, Luc G. Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrate. J Biol Chem. 2001;276:25841-25847.
15. Watts GF, Barrett PH, Ji J, Serone AP, Chan DC, Croft KD, Loehrer F, Johnson AG. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. Diabetes. 2003;52:803-811.
16. van der Kallen CJ, Cantor RM, van Greevenbroek MM, Geurts JM, Bouwman FG, Aouizerat BE, Allayee H, Buurman WA, Lusis AJ, Rotter JI, de Bruin TW. Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily IA. Int J Obes Relat Metab Disord. 2000;24:1381-1391.
17. Aouizerat BE, Allayee H, Cantor RM, Davis RC, Lanning CD, Wen PZ, Dallinga-Thie GM, de Bruin TW, Rotter JI, Lusis AJ. A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. Am J Hum Genet. 1999;65:397-412.
18. Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat Genet. 2002;30:110-116.
19. Pajukanta P, Bodnar JS, Sallinen R, Chu M, Airaksinen T, Xiao Q, Castellani LW, Sheth SS, Wessman M, Palotie A, Sinsheimer JS, Demant P, Lusis AJ, Peltonen L. Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL. Mamm Genome. 2001;12:238-245.
20. Aouizerat BE, Allayee H, Bodnar J, Krass KL, Peltonen L, de Bruin TW, Rotter JI, Lusis AJ. Novel genes for familial combined hyperlipidemia. Curr Opin Lipidol. 1999;10:113-122.