Organization of the human FK506-binding immunophilin FKBP52 protein gene (FKBP4)

Genomics

Volumn 81, Issue 6, 2003, Pages 640-643

  Scammell, Jonathan G ^a   Hubler, Tina R ^a   Denny, Wesley B ^a   Valentine, Donna L ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Exons; FK506; Genes, reporter; Immunophilin; Introns; Luciferase; Promoter; Transcription factors

Indexed keywords

AMINO ACID; CYSTEINYLALANYLALANYLTHREONINE; HEAT SHOCK PROTEIN; IMMUNOPHILIN; LUCIFERASE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; TACROLIMUS; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CELL STRAIN; CELL STRAIN COS7; CELL STRAIN MCF 7; DNA FLANKING REGION; DNA VECTOR; DRUG BINDING; EXON; GENE ACTIVITY; GENE CONSTRUCT; GENE DELETION; GENE SEQUENCE; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC CONSERVATION; GENETIC ORGANIZATION; GENOMICS; HUMAN; HUMAN GENOME; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN MOTIF; REPORTER GENE; SEQUENCE ANALYSIS; SPECIES COMPARISON; STRUCTURE ANALYSIS;

ORYCTOLAGUS CUNICULUS;

EID: 0037686296     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0888-7543(03)00090-9     Document Type: Article

References (31)

1. Tai P.K., Faber L.E. Isolation of dissimilar components of the 8.5S nonactivated uterine progestin receptor. Can. J. Biochem. Cell. Biol. 63:1985;41-49.
2. Lebeau M.C., et al. P59, an hsp 90-binding protein. Cloning and sequencing of its cDNA and preparation of a peptide-directed polyclonal antibody, J. Biol. Chem. 267:1992;4281-4284.
3. Peattie D.A., et al. Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. Proc. Natl. Acad. Sci. USA. 89:1992;10974-10978.
4. Schmitt J., Pohl J., Stunnenberg H.G. Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor. Gene. 132:1993;267-271.
5. Nair S.C., et al. Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor. Mol. Cell. Biol. 17:1997;594-603.
6. Tai P.K., et al. A 59-kilodalton protein associated with progestin, estrogen, androgen, and glucocorticoid receptors. Biochemistry. 25:1986;5269-5275.
7. Pratt W.B., Toft D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18:1997;306-360.
8. Radanyi C., Chambraud B., Baulieu E.E. The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain. Proc. Natl. Acad. Sci. USA. 91:1994;11197-111201.
9. Galigniana M.D., Radanyi C., Renoir J.M., Housley P.R., Pratt W.B. Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. J. Biol. Chem. 276:2001;14884-14889.
10. Reynolds P.D., Ruan Y., Smith D.F., Scammell J.G. Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. J. Clin. Endocrinol. Metab. 84:1999;663-669.
11. Scammell J.G., Denny W.B., Valentine D.L., Smith D.F. Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates. Gen. Comp. Endocrinol. 124:2001;152-165. doi:10.1006/gcen.2001.7696.
12. Mamane Y., Sharma S., Petropoulos L., Lin R., Hiscott J. Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52. Immunity. 12:2000;129-140.
13. Guo Y., et al. Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex. J. Biol. Chem. 276:2001;45791-45799.
14. Railson J.E., Lawrence K., Buddle J.C., Pennica D., Latchman D.S. Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect. J. Mol. Cell. Cardiol. 33:2001;1209-1221.
15. Gold B.G., Densmore V., Shou W., Matzuk M.M., Gordon H.S. Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. J. Pharmacol. Exp. Ther. 289:1999;1202-1210.
16. Qing K., et al. Adeno-associated virus type 2-mediated gene transfer role of cellular FKBP52 protein in transgene expression . J. Virol. 75:2001;8968-8976.
17. Goel M., Garcia R., Estacion M., Schilling W.P. Regulation of Drosophila TRPL channels by immunophilin FKBP59. J. Biol. Chem. 276:2001;38762-38773.
18. Bermingham N.A., et al. The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12. Mamm. Genome. 9:1998;268.
19. Patterson C.E., Gao J., Rooney A.P., Davis E.C. Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family. Genomics. 79:2002;881-889. doi:10.1006/geno.2002.6777.
20. Mount S.M. A catalogue of splice junction sequences. Nucleic Acids Res. 10:1982;459-472.
21. Yokoi H., et al. The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene. Genomics. 35:1996;448-455.
22. Ward B.K., Mark P.J., Ingram D.M., Minchin R.F., Ratajczak T. Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer. Breast Cancer Res. Treat. 58:1999;267-280.
23. Heinemeyer T., et al. Databases on transcriptional regulation TRANSFAC, TRRD and COMPEL . Nucleic Acids Res. 26:1998;362-367.
24. Philipsen S., Suske G. A tale of three fingers the family of mammalian Sp/XKLF transcription factors . Nucleic Acids Res. 27:1999;2991-3000.
25. Kroeger P.E., Morimoto R.I. Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity. Mol. Cell. Biol. 14:1994;7592-7603.
26. Sarge K.D., Park-Sarge O.K., Kirby J.D., Mayo K.E., Morimoto R.I. Expression of heat shock factor 2 in mouse testis potential role as a regulator of heat-shock protein gene expression during spermatogenesis . Biol. Reprod. 50:1994;1334-1343.
27. Mark P.J., et al. Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock. Cell Stress Chaperones. 6:2001;59-70.
28. Blackwell T.K., et al. Binding of myc proteins to canonical and noncanonical DNA sequences. Mol. Cell. Biol. 13:1993;5216-5224.
29. Coller H.A., et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc. Natl. Acad. Sci. USA. 97:2000;3260-3265.
30. T.R. Hubler, et al., The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness, Endocrinology (in press).
31. Kumar P., Ward B.K., Minchin R.F., Ratajczak T. Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for GA-binding protein (GABP). Cell Stress Chaperones. 6:2001;78-91.