Transformations of testosterone and related steroids in Absidia glauca culture

Journal of Basic Microbiology

Volumn 43, Issue 2, 2003, Pages 113-120

  Huszcza, Ewa ^a   Dmochowska Gladysz, Jadwiga ^a  

^a WROC AW UNIVERSITY OF ENVIRONMENTAL AND LIFE SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ABSIDIA; BIOTRANSFORMATION; TESTOSTERONE;

ABSIDIA; ABSIDIA GLAUCA; FUNGI;

EID: 0037680425     PISSN: 0233111X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jobm.200390011     Document Type: Article

References (19)

1. APPLEZWEIG, N., 1962, Modified steroids hormones. In: Steroid Drugs, pp. 87-123. McGraw-Hill Book Company New York.
2. BRZEZOWSKA, E., DMOCHOWSKA-DLADYSZ, J. and KOLEK, T., 1996. Biotransformation XXXIX. Metabolism of testosterone, androstendione, progesterone and testosterone derivatives in Absidia coerulea culture. J. Steroid Biochem. Molec. Biol., 57, 357-362.
3. CHARNEY, W. and HWRZOG, H. L., 1967. In: Microbial Transformation of Steroids, pp. 269-273. Academic Press, New York and London.
4. CLEGG, A. S., JONES, E. R. H., MEAKINS, G. D. and PINHEY, J. T., 1970. The preparation of 1β, 11α-dihydroxy-steroids by microbiological hydroxylation. Chem. Commun., 1029.
5. GRIFFITHS, D. A., BEST, D. J. and JEZEQUEL, S. G., 1991. The screening of selected microorganisms for use as models of mammalian drug metabolism. Appl. Microbiol. Biotechnol., 35, 373-381.
6. HANSON, J. R., NASIR, H. and PARVEZ, A., 1996. The hydroxylation of testosterone and some relatives by Cephalosporium aphidicola. Phytochemistry, 42, 411-415.
7. HOLLAND, H. L. and DIAKOW, P. R. P., 1978. The mechanism of the microbial hydroxylation of steroids. Part 4, The C-6β hydroxylation of androst-4-ene-3,17-dione and related compounds by Rhizopus arrhizus ATCC 11145. Can. J. Chem., 56, 694-702.
8. HOLLAND, H. L., 1999. Recent advances in applied and mechanistic aspects of enzymatic hydroxylation of steroids by whole-cell biocatalysts. Steroids, 64, 178-186.
9. JONES, E. R. H., 1973. The microbiological hydroxylation of steroids and related compounds. Pure Appl. Chem., 32, 39-52.
10. 1H NMR spectra of the steroid hormones, their hydroxylated derivatives, and related compounds. J. Chem. Perkin Trans., 2, 1567-1594.
11. 4,9(10)-19-norsteroid drug. Bioorg. Med. Chem., 7, 2329-2341.
12. MAHATO, S. B., BANERJEE, S. and PODDER, S., 1989. Steroid transformations by microorganisms - III. Phytochemistry, 28, 7-40.
13. SCHUBERT, K., SCHLEGEL, J., GROH, H., ROSE, G. and HÖRHOLD, C., 1972. Hörhold, Stoffwechsel von Steroidpharmaka VII. Struktur-Stoffwechsel-Bezichungen bei der mikrobiellen Hydrierung unterschiedlich substituierter Testosteronderivate. Endokrinologie, 59, 99-114.
14. SEDLACZEK, L., 1988. Biotransformations of steroids. CRC Crit. Rev. Biotechnol., 7, 187-236.
15. SHIRASAKA, M., OZAKI, M. and SUGAWARA, S., 1961. Microbiological transformation of steriod compounds. J. Gen. Appl. Microbiol., 7, 341-352
16. SMITH, R. V. and ROSAZZA, J. P., 1975. Microbial models of mammalian metabolism. J. Pharm. Sci., 64, 1737-1759.
17. TRUCKENBRODT, G., LANGBEIN, G., AUWEILER, J. and HENKEL H., 1991. Manufacture of pregnanes with Absidia. East Ger. Patent 292, 675.
18. WANG, J., CHEN, C., LI, B. LI, ZHANG, J. and YU, Y., 1998. Production of hydrocortisone from cortexolone-21-acetate by immobilized Absidia orchidis in cosolvent-containing media. Enzyme Microb. Technol., 22, 368-373.
19. ZHOU, W. S. and YIN, Z. H., 1980. Hydroxylation of 16-dehydroprogesterone by Absidia orchidis. Hua Hsueh Hsueh Pao, 38, 467-474.