Expression of Cox-2, Tie-2 and glycodelin by megakaryocytes in patients with chronic myeloid leukaemia and polycythaemia vera

British Journal of Haematology

Volumn 121, Issue 3, 2003, Pages 497-499

  Zetterberg, Eva ^a   Lundberg, Lars Göran ^b   Palmblad, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

Chronic myeloid leukaemia; Cox 2; Glycodelin; Polycythaemia vera; Tie 2

Indexed keywords

ANGIOPOIETIN RECEPTOR; BIOLOGICAL MARKER; CYCLOOXYGENASE 2; PLACENTA PROTEIN 14; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; BONE MARROW BIOPSY; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; MEGAKARYOCYTE; MEGAKARYOPOIESIS; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CYCLOOXYGENASE 2; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; LEUKEMIA, MYELOID, CHRONIC; MEGAKARYOCYTES; MEMBRANE PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; POLYCYTHEMIA VERA; PREGNANCY PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-2;

EID: 0037677920     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04289.x     Document Type: Article

References (9)

1. Davis, S., Aldrich, T.H., Jones, P.F., Acheson, A., Compton, D.L., Jain, V., Ryan, T.E., Bruno, J., Radziejewski, C., Maisonpierre, P.C. & Yancopoulos, G.D. (1996) Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell. 87, 1161-1169.
2. Kamarainen, M., Miettinen, M., Seppala, M., von Boguslawsky, K., Benassi, M.S., Bohling, T. & Andersson, L.C. (1998) Epithelial expression of glycodelin in biphasic synovial sarcomas. Internal Journal of Cancer, 76, 487-490.
3. Lundberg, L.G., Lerner, R., Sundelin, P., Rogers, R., Folkman, J. & Palmblad, J. (2000) Bone marrow in polycythemia vera, chronic myelocytic leukemia, and myelofibrosis has an increased vascularity. American Journal of Pathology, 157, 15-19.
4. Masferrer, J.L., Leahy, K.M., Koki, A.T., Zweifel, B.S., Settle, S.L., Woerner, B.M., Edwards, D.A., Flickinger, A.G., Moore, R.J. & Seibert, K. (2000) Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Research, 60, 1306-1311.
5. Morrow, D.M., Xiong, N., Getty, R.R., Ratajczak, M.Z., Morgan, D., Seppala, M., Riittinen, L., Gewirtz, A.M. & Tykocinski, M.L. (1994) Hematopoietic placental protein 14. An immuno-suppressive factor in cells of the megakaryocytic lineage. American Journal of Pathology, 145, 1485-1495.
6. Reusch, P., Barleon, B., Weindel, K., Martiny-Baron, G., Godde, A., Siemeister, G. & Marine, D. (2001) Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood. Angiogenesis. 4, 123-131.
7. Rocca, B., Secchiero, P., Ciabattoni, G., Ranelletti, F.O., Catani, L., Guidotti, L., Melloni, E., Maggiano, N., Zauli, G. & Patrono, C. (2002) Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets. Proceedings of the National Academy of Sciences of the United States of America. 99, 7634-7639.
8. Sato, T.N., Qin, Y., Kozak, C.A. & Audus, K.L. (1993) Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system. Proceedings of the National Academy of Sciences of the United States of America, 90, 9355-9358.
9. Song, M., Ramaswamy, S., Ramachandran, S., Flowers, L.C., Horowitz, I.R., Rock, J.A. & Parthasarathy, S. (2001) Angiogenic role for glycodelin in tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 98, 9265-9270.