Method of birth alters interferon-gamma and interleukin-12 production by cord blood mononuclear cells

Pediatric Allergy and Immunology

Volumn 14, Issue 2, 2003, Pages 106-111

  Brown, Mark A ^a,b   Rad, Parmis Y ^a,b   Halonen, Marilyn J ^a,b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cesarean section; Cord blood mononuclear cells; Cytokines; Labor

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ;

ARTICLE; CELL FUNCTION; CELL ISOLATION; CESAREAN SECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELIVERY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; LABOR; MONONUCLEAR CELL; PRIORITY JOURNAL; UMBILICAL CORD BLOOD; VAGINAL DELIVERY;

DELIVERY, OBSTETRIC; FEMALE; FETAL BLOOD; HUMANS; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; LEUKOCYTES, MONONUCLEAR;

EID: 0037677606     PISSN: 09056157     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3038.2003.00015.x     Document Type: Article

References (18)

1. TRIVEDI HN, HAYGLASS KT, GANUR V, et al. Analysis of neonatal T cell and antigen presenting functions. Human Immunol 1997: 57: 69-79.
2. SAUTIS B, FILLET G, BEGUIN Y. Comparative cytokine production by in vitro stimulated mononucleated cells from cord blood and adult blood. Exp Hematol 1997: 25: 103-8.
3. QIAN JX, LEE SM, SUEN Y, et al. Decreased interleukin-15 from activated cord versus adult peripheral blood mononuclear cells and the effect of interleukin15 in upregulating antitumor immune activity and cytokine production in cord blood. Blood 1997: 90: 3106-17.
4. CHALMERS IMH, JANOSSY G, CONTRERAS M, NAVARETTE C. Intracellular cytokine profile of cord and adult blood lymphocytes. Blood 1998: 92: 11-8.
5. PILLAY V, SAVAGE N, LABURN H. Circulating cytokine concentrations and cytokine production by monocytes from newborn babies and adults. Pediatr Res 1994: 428: 197-201.
6. SCHIBLER KR, LIECHTY KW, WHITE WL, et al. Defective production of interleukin-6 by monocytes: a possible mechanism underlying several host defense deficiencies of neonates. Pediatr Res 1992: 31: 18-21.
7. DOMINGUEZ E, MADRIGAL JA, LAYRISSE Z, et al. Fetal natural killer cell function is suppressed. Immunology 1998: 94: 109-14.
8. BERGER M. Complement deficiency and neutrophil dysfunction as risk factors for bacterial infection in newborns and the role of granulocyte transfusion in therapy. Rev Infect Dis 1990: 12: S401-S409.
9. TANG ML, KEMP AS, THORBURN J, HILL DJ. Reduced interferon-γ secretion in neonates and subsequent atopy. Lancet 1994: 344: 983-5.
10. HALONEN M, MARTINEZ FD. A deficient capacity to produce interferon-gamma: is it a risk for asthma and allergies? Clin Exp Allergy 1997: 27: 1234-6.
11. FRAZIER JP, KOHL S, PICKERING LK, LOO L-S. The effect of route of delivery on neonatal natural killer cytotoxicity and antibody-dependent cellular cytotoxicity in herpes simplex virus infected cells. Pediatr Res 1982: 16: 558-60.
12. PITTARD WB, MILLER K, SORENSEN RU. Normal lymphocyte responses to mitogens in term and premature neonates following normal and abnormal intrauterine growth. Clin Immunol Immunopathol 1984: 30: 178-87.
13. PITTARD WB, MILLER KM, SORENSEN RU. Perinatal influences on in vitro neonatal B lymphocyte differentiation in human neonates. Pediatr Res 1985: 19: 655-8.
14. PITTARD WB, SCHLEICH DM, GEDDES KM, SORENSEN RU. Newborn lymphocyte subpopulations: the influence of labor. Am J Obstet Gynecol 1989: 160: 151-4.
15. SCOTT ME, KUBIN M, KOHL S. High level interleukin-12 production, but diminished interferon-γ production, by cord blood mononuclear cells. Pediatr Res 1997: 41: 547-53.
16. LEE SM, SUEN Y, CHANG L, et al. Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferon-γ, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cells. Blood 1996: 88: 945-54.
17. CHAN SH, PERUSSIA B, GUPTA JW, et al. Induction of interferon-γ production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med 1991: 173: 869-79.
18. JOKIC M, GUILLOIS B, CAUQUELIN B, et al. Fetal distress increases interleukin-6 and interleukin-8 and decreases tumour necrosis factor-α cord blood levels in noninfected full-term neonates. Br J Obstet Gynaecol 2000: 107: 420-5.