An overview on the antileukemic potential of D-homo-aza- and respective 17β-acetamido-steroidal alkylating esters

Investigational New Drugs

Volumn 21, Issue 1, 2003, Pages 47-54

  Camoutsis, Charalambos ^a   Trafalis, Dimitrios T P ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Acetamido steroidal esters; Acute toxicity; Alkylators; Homo aza steroids; Human leukemia cell lines; L1210 lymphoid leukemia; P388 lymphocytic leukemia

Indexed keywords

17BETA ACETAMIDOSTEROIDAL ALKYLATING ESTER DERIVATIVE; ALKYLATING AGENT; ANTILEUKEMIC AGENT; CHLORAMBUCIL; CHLORMETHINE; CYCLOPHOSPHAMIDE; DEXTRO HOMOAZASTEROIDAL ALKYLATING ESTER DERIVATIVE; MELPHALAN; MITOMYCIN C; THIOTEPA; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LD 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; AZASTEROIDS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ESTERS; FEMALE; HUMANS; INJECTIONS, INTRAPERITONEAL; LETHAL DOSE 50; LEUKEMIA, EXPERIMENTAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; STRUCTURE-ACTIVITY RELATIONSHIP; SURVIVAL RATE;

EID: 0037677425     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022964225715     Document Type: Review

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