Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface

Biochemical Pharmacology

Volumn 66, Issue 1, 2003, Pages 43-50

  Conran, Nicola ^a,c   Gambero, Alessandra ^b   Ferreira, Heloisa H A ^b   Antunes, Edson ^a   De Nucci, Gilberto ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b USF   (Brazil)

^c NONE   (Brazil)

Author keywords

Adhesion molecules; Cytoskeleton; Mac 1; Neutrophil; Nitric oxide synthase inhibitors; VLA 4

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ALPHA4 INTEGRIN; BETA1 INTEGRIN; BETA2 INTEGRIN; CD11B ANTIGEN; DIHYDROCHALASIN B; FIBRONECTIN; ICRF 44; INTEGRIN; MAC 1 INTEGRIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HP2 1; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NOCODAZOLE; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MODULATION; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SERUM;

EID: 0037667908     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00243-0     Document Type: Article

References (53)

1. Ley K., Tedder T.F., Kansas G.S. L-Selectin can mediate leukocyte rolling in untreated mesenteric vesicles in vivo independently of E- or P-selectin. Blood. 82:1993;1632-1638.
2. Moore K.L., Patel K.D., Brehl R.E., Johnson D.A., Lichenstein H.S., Cummings R.D., Bainton D.F., Mcever R.P. P-Selectin glycoprotein mediates rolling of human neutrophils on P-selectin. J. Cell Biol. 128:1995;661-671.
3. Issekutz A.C., Issekutz T.B. The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of PMN leukocytes to inflammatory reactions in the rat. Immunology. 76:1992;655-661.
4. Alon R., Kassner P.P., Carr M.W., Finger E.B., Hemler M.E., Springer T.A. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J. Cell Biol. 128:1995;1243-1253.
5. Issekutz A.C., Issekutz T.B. Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and VLA-4 integrin mechanisms. J. Exp. Med. 181:1995;1197-1203.
6. Doerschuk C.M., Winn R.K., Coxson H.O., Harlan J.M. CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J. Immunol. 144:1990;2327-2333.
7. Issekutz A.C., Issekutz T.B. A major portion of polymorphonuclear leukocyte and T lymphocyte migration to arthritic joints in the rat is via LFA-1/Mac-1-independent mechanisms. Clin. Immunol. Immunopathol. 67:1993;257-263.
8. Burns J.A., Issekutz T.B., Yagita H., Issekutz A.C. The alpha 4 beta 1 (very late antigen (VLA)-4, CD49d/CD29 and alpha 5 beta 1 (VLA-5, CD49e/CD29) integrins mediate beta 2 (CD11/CD18) integrin-independent neutrophil recruitment to endotoxin-induced lung inflammation. J. Immunol. 166:2001;4644-4649.
9. 1-dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigration. FASEB J. 9:1995;1103-1111.
10. 1-integrin under flow conditions. Blood. 89:1997;3837-3846.
11. 1 integrin, VLA-4 on human neutrophils can contribute to neutrophil migration through connective tissue fibroblast barriers. Immunology. 90:1997;448-454.
12. Shang T., Yednock T., Issekutz A.C. Alpha9beta1 integrin is expressed on human neutrophils and contributes to neutrophil migration through human lung and synovial fibroblast barriers. J. Leukoc. Biol. 66:1999;809-816.
13. Belenky S.N., Robbins R.A., Rennard S.I., Gossman G.L., Nelson K.J., Rubinstein I. Inhibitors of nitric oxide attenuate neutrophil chemotaxis in vitro. J. Lab. Clin. Med. 122:1993;388-394.
14. Moilanen E., Vuorinen H., Kankaanranta H., Metsa-Ketela T., Vapaatalo H. Inhibition by nitric oxide-donors of human PMN leucocyte functions. Br. J. Pharmacol. 109:1993;852-858.
15. Wanikiat P., Woodward D.F., Armstrong R.A. Investigation into the role of nitric oxide and cGMP in both the activation and inhibition of human neutrophils. Br. J. Pharmacol. 122:1997;1135-1145.
16. G-monomethyl-L-arginine: a role for cyclic GMP. Blood. 74:1989;1885-1887.
17. Kosonen O., Kankaanranta H., Malo-Ranta U., Moilanen E. Nitric-oxide releasing compounds inhibit neutrophil adhesion to endothelial cells. Eur. J. Pharmacol. 382:1999;111-117.
18. Kosonen O., Kankaanranta H., Uotila J., Moilanen E. Inhibition by nitric oxide-releasing compounds of E-selectin expression in and neutrophil adhesion to human endothelial cells. Eur. J. Pharmacol. 394:2000;149-156.
19. Kubes P., Suzuki M., Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. U.S.A. 88:1991;4651-4655.
20. Wagner J.G., Roth R.A. Neutrophil migration mechanisms with an emphasis on the pulmonary vasculature. Pharmacol. Rev. 52:2000;349-374.
21. Bradley P.P., Priebat D.A., Christensen R.D., Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:1982;206-209.
22. Lefer D.J., Jones S.P., Girod W.G., Baines A., Grisham M.B., Cockerell A.S., Huang P.L., Scalia R. Leukocyte-endothelial cell interactions in nitric oxide synthase deficient mice. Am. J. Physiol. 276:1999;H1943-H1950.
23. Sanz M.J., Hickey M.J., Jonhston B., McCafferty D.M., Raharjo E., Huang P.L., Kubes P. Neuronal nitric oxide synthase (NOS) regulates leukocyte-endothelial cell interactions in endothelial NOS deficient mice. Br. J. Pharmacol. 134:2001;305-312.
24. Thomazzi S.M., Ferreira H.H., Conran N., de Nucci G., Antunes E. Role of nitric oxide on in vitro human eosinophil migration. Biochem. Pharmacol. 62:2001;1417-1421.
25. Ferreira H.H.A., Medeiros M.V., Lima C.S.P., Flores C.A., Sannomiya P., Antunnes E., de Nucci G. Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis. Eur. J. Pharmacol. 310:1996;201-207.
26. Lee S.K., Kim J.H., Yang W.S., Kim S.B., Park S.K., Park J.S. Exogenous nitric oxide inhibits VCAM-1 expression in human peritoneal mesothelial cells. Role of cyclic GMP and NF-kappaB. Nephron. 90:2002;447-454.
27. De Caterina R., Libby P., Peng H.B., Thannickal V.J., Rajavashisth T.B., Gimbrone M.A. Jr., Shin W.S., Liao J.K. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96:1995;60-68.
28. Pigott R, Power C. The adhesion molecule fact book. London: Academic Press; 1993.
29. 1-mediated function. J. Cell Biol. 138:1997;1437-1447.
30. Feigelson S.W., Grabovsky V., Winter E., Chen L.L., Pepinsky R.B., Yednock T., Yablonski D., Lobb R., Alon R. The Src kinase p56 (Ick) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin. J. Biol. Chem. 276:2001;13891-13901.
31. Monteiro H.P., Gruia-Gray J., Peranovich T.M., de Oliveira L.C., Stern A. Nitric oxide stimulates tyrosine kinase phosphorylation of focal adhesion kinase, Src kinase and mitogen-activated protein kinases in murine fibroblasts. Free Radic. Biol. Med. 28:2000;174-182.
32. 2 integrin. J. Biol. Chem. 271:1996;18211-18216.
33. Rochon Y.P., Kavanagh T.J., Harlan J.M. Analysis of integrin (CD11b/CD18) movement during neutrophil adhesion and migration on endothelial cells. J. Microsc. 197:2000;15-24.
34. Ley K. Molecular mechanisms of leukocyte recruitment in the inflammatory process. Cardiovasc. Res. 32:1996;733-742.
35. Hofman P., d'Andrea L., Guzman E., Selva E., Le Negrate G., Far D.F., Lemichez E., Boquet P., Rossi B. Neutrophil F-actin but not microtubule functionally regulate transepithelial migration induced by interleukin-8 across a cultured intestinal epithelial monolayer. Eur. Cytokine Netw. 10:1999;227-236.
36. Zhou X., Li J., Kucik D.F. The microtubule cytoskeleton participates in control of beta 2 integrin avidity. J. Biol. Chem. 276:2001;44762-44769.
37. Anderson S.I., Hotchin N.A., Nash G.B. Role of the cytoskeleton in rapid activation of CD11b/CD18 function and its subsequent downregulation in neutrophils. J. Cell Sci. 113:2000;2737-2745.
38. Frenkel S.R., Clancy R.M., Ricci J.L., Di Cesare P.E., Rediske J.J., Abramson S.B. Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly. Arthritis Rheum. 39:1996;1905-1912.
39. Govers R., Bevers L., de Bree P., Rabelink T.J. Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts. Biochem. J. 361:2002;193-201.
40. Webb J.L., Polak J.M., Evans T.J. Effect of adhesion on inducible nitric oxide (iNOS) production in purified human neutrophils. Clin. Exp. Immunol. 123:2001;42-48.
41. Wallerath T., Gath I., Aulitzky W.E., Pollock J.S., Kleinert H., Forstermann U. Identification of the NOS synthase isoforms expressed in human neutrophil granulocytes, megakaryocytes and platelets. Thromb. Haemost. 77:1997;163-167.
42. Salvemini D., de Nucci G., Gryglewski R.J., Vane J.R. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc. Natl. Acad. Sci. U.S.A. 86:1989;6328-6332.
43. Goode H.F., Webster N.R., Howdle P.D., Walker B.E. Nitric oxide production by human peripheral blood polymorphonuclear leucocytes. Clin. Sci. 86:1994;411-415.
44. Babu B.R., Griffith O.W. Design of isoform-selective inhibitors of nitric oxide synthase. Curr. Opin. Chem. Biol. 2:1998;491-500.
45. Giraldelo C.M., Zappellini A., Muscara M.N., De luca I.M., Hyslop S., Cirino G., Zatz R., De Nucci G., Antunes E. Effect of arginine analogues on rat hind paw oedema and mast cell activation in vitro. Eur. J. Pharmacol. 257:1994;87-93.
46. Conran N., Ferreira H.H.A., Lorand-Metze I., Thomazzi S.M., Antunes E., de Nucci G. Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface. Br. J. Pharmacol. 134:2001;632-638.
47. Wegener J.W., Closs E.I., Forstermann U., Nawrath H. Failure of 1H-[1,2,4] oxadiazolo quinoxalin-1-one (ODQ) to inhibit soluble guanylyl cyclase in rat ventricular cardiomyocytes. Br. J. Pharmacol. 127:1999;693-700.
48. Niu X.-F., Smith W., Kubes P. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils. Circ. Res. 74:1994;1133-1140.
49. 2-integrins and their cellular ligands. Eur. J. Biochem. 245:1997;215-232.
50. Okayama N., Coe L., Itoh M., Alexander J.S. Exogenous nitric oxide increases neutrophil adhesion to cultured human endothelial monolayers through a protein kinase G dependent mechanism. Inflammation. 23:1999;37-50.
51. Ischiropaulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch. Biochem. Biophys. 356:1998;1-11.
52. Kausalya S., Nath J. Interactive role of nitric oxide and superoxide anion in neutrophil-mediated endothelial cell injury. J. Leukoc. Biol. 64:1998;185-191.
53. Fraticelli A., Serrano C.V. Jr., Bochner B.S., Capogrossi M.C., Zweier J.L. Hydrogen peroxide and superoxide modulate leukocyte adhesion molecule expression and leukocyte endothelial adhesion. Biochim. Biophys. Acta. 1310:1996;251-259.