Ischemic preconditioning is not cardioprotective in senescent human myocardium

Annals of Thoracic Surgery

Volumn 76, Issue 1, 2003, Pages 105-111

  Bartling, Babett ^a   Friedrich, Ivar ^a   Silber, Rolf E ^a   Simm, Andreas ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEAT SHOCK PROTEIN 70;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DISEASE SIMULATION; HEART INFARCTION PREVENTION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RIGHT ATRIUM; HUMAN; HUMAN TISSUE; ISCHEMIC HEART DISEASE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REOXYGENATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; STATISTICAL SIGNIFICANCE;

ADULT; AGE FACTORS; AGED; AGING; BASE SEQUENCE; CORONARY DISEASE; CULTURE TECHNIQUES; ELASTICITY; FEMALE; HEART ARREST, INDUCED; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PROBABILITY; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RNA, MESSENGER;

EID: 0037662205     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(03)00186-3     Document Type: Article

References (31)

1. Reynen K, Bachmann K. Coronary arteriography in elderly patients: risk, therapeutic consequences and long-term follow-up. Coron Artery Dis 1997;8:657-66.
2. Hirose H, Amano A, Yoshida S, Takahashi A, Nagano N, Kohmoto T. Coronary artery bypass grafting in the elderly. Chest 2000;117:1262-70.
3. Goldberg RJ, Gore JM, Gurwitz JH, et al. The impact of age on the incidence and prognosis of initial acute myocardial infarction: the Worcester Heart Attack Study. Am Heart J 1989;117:543-9.
4. Mariani J, Ou R, Bailey M, et al. Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J Thorac Cardiovasc Surg 2000;120:660-7.
5. Cohen MV, Liu GS, Downey JM. Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits. Circulation 1991;84:341-9.
6. Walker DM, Walker JM, Pugsley WB, Pattison CW, Yellon DM. Preconditioning in isolated superfused human muscle. J Mol Cell Cardiol 1995;27:1349-57.
7. Kelion AD, Webb TP, Gardner MA, Ormerod OJ, Banning AP. The warm-up effect protects against ischemic left ventricular dysfunction in patients with angina. J Am Coll Cardiol 2001;37:705-10.
8. Kloner RA, Shook T, Przyklenk K, et al. Previous angina alters in-hospital outcome in TIMI 4. A clinical correlate to preconditioning? Circulation 1995;91:37-45.
9. Lu EX, Chen SX, Yuan MD, et al. Preconditioning improves myocardial preservation in patients undergoing open heart operations. Ann Thorac Surg 1997;64:1320-4.
10. Abete P, Ferrara N, Cioppa A, et al. Preconditioning does not prevent postischemic dysfunction in aging heart. J Am Coll Cardiol 1996;27:1777-86.
11. Abete P, Ferrara N, Cacciatore F, et al. Angina-induced protection against myocardial infarction in adult and elderly patients: a loss of preconditioning mechanism in the aging heart? J Am Coll Cardiol 1997;30:947-54.
12. Napoli C, Liguori A, Cacciatore F, Rengo F, Ambrosio G, Abete P. "Warm-up" phenomenon detected by electrocardiographic ambulatory monitoring in adult and older patients. J Am Geriatr Soc 1999;47:1114-7.
13. Knowlton A, Brecher P, Apstein C. Rapid expression of heat shock proteins in the rabbit after brief cardiac ischemia. J Clin Invest 1991;87:139-47.
14. Ghosh S, Standen NB, Galinanes M. Preconditioning the human myocardium by simulated ischemia: studies on the early and delayed protection. Cardiovasc Res 2000;45:339-50.
15. Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P. Regional ischemic preconditioning protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 1993;87:893-9.
16. Tomai F, Crea F, Chiariello L, Gioffre PA. Ischemic preconditioning in humans: models, mediators, and clinical relevance. Circulation 1999;100:559-63.
17. Tani M, Suganuma Y, Hasegawa H, et al. Changes in ischemic tolerance and effects of ischemic preconditioning in middle-aged rat hearts. Circulation 1997;95:2559-66.
18. Longobardi G, Abete P, Ferrara N, et al. "Warm-up" phenomenon in adult and elderly patients with coronary artery disease: further evidence of the loss of "ischemic preconditioning" in the aging heart. J Gerontol A Biol Sci Med Sci 2000;55:M124-9.
19. Wu ZK, Tarkka MR, Pehkonen E, et al. Beneficial effects of ischemic preconditioning on right ventricular function after coronary artery bypass grafting. Ann Thorac Surg 2000;70:1551-7.
20. Mild T, Miura T, Tsuchida A, et al. Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation. Circulation 2000;102:458-63.
21. Suematsu Y, Ohtsuka T, Horimoto H, et al. Long-term treatment with nipradilol, a nitric oxide-releasing beta-adrenergic blocker, enhances postischemic recovery and limits infarct size. Ann Thorac Surg 2002;73:173-9.
22. Nakano A, Liu GS, Heusch G, Downey JM, Cohen MV. Exogenous nitric oxide can trigger a preconditioned state through a free radical mechanism, but endogenous nitric oxide is not a trigger of classical ischemic preconditioning. J Mol Cell Cardiol 2000;32:1159-67.
23. Ghosh S, Standen NB, Galinianes M. Failure to precondition pathological human myocardium. J Am Coll Cardiol 2001;37:711-718.
24. Tomai F, De Paulis R, Penta de Peppo A, et al. Beneficial impact of isoflurane during coronary bypass surgery on troponin I release. G Ital Cardiol 1999;29:1007-14.
25. Cohen MV, Yang XM, Downey JM. Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning. Circ Res 1994;74:998-1004.
26. Yellon DM, Dana A. The preconditioning phenomenon. Circ Res 2000;87:543-50.
27. Benjamin IJ, McMillan DR. Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease. Circ Res 1998;83:117-32.
28. Heads R, Latchman D, Yellon DM. Differential stress protein expression during early ischemic preconditioning in the rabbit heart and its relationship to adenosine receptor function. J Mol Cell Cardiol 1995;27:2133-48.
29. Zhong H, Simons JW. Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia. Biochem Biophys Res Comm 1999;259:523-6.
30. Van Nieuwenhoven FA, Martin X, Heijnen VVT, Conrnelussen RN, Snoeckx LHEH. HSP70-mediated acceleration of transcriptional recovery after stress is independent of ribosomal RNA synthesis. Eur J Cell Biol 2001;80:586-92.
31. Hamilton KL, Powers SK, Sugiura T, et al. Short-term exercise training can improve myocardial tolerance to I/R without elevation in heat shock proteins. Am J Physiol 2001;281:H1346-52.