The dual pathway electrophysiology of the atrioventricular conduction: A new look at an old phenomenon

Minerva Cardioangiologica

Volumn 51, Issue 1, 2003, Pages 1-14

  Mazgalev, T N ^a   Zhang, Y ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Atrioventricular node, physiology; Electrophysiology; Tachycardia Atrioventricular nodal reentry

Indexed keywords

ATRIOVENTRICULAR CONDUCTION; ELECTROGRAPHY; ELECTROPHYSIOLOGY; EXPERIMENTATION; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM FIBRILLATION; HEART CONDUCTION; HIS BUNDLE POTENTIAL; NERVE POTENTIAL; REVIEW;

ANIMALS; ATRIAL FIBRILLATION; ATRIOVENTRICULAR NODE; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; HEART CONDUCTION SYSTEM; HUMANS;

EID: 0037651193     PISSN: 00264725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (40)

1. Mazgalev TN, Ho SY, Anderson RH. Anatomic-electrophysiological correlations concerning the pathways for atrioventricular conduction. Circulation 2001;103:2660-7.
2. Kent AFS. Researches on the structure and function of the mammalian heart. J Physiol 1893;14:233-54.
3. Mines GR. On circulating excitations in heart muscles and their possible relation to tachycardia and fibrillation. J Trans Soc Can 1914;4:43-50.
4. His W jr. Die Tatigkeit des embryonalen Herzens und deren Bedeutung fur die Lehre von der Herzbewegung beim Erwachsenen. Arbeiten aus der Medizinischen Klinik zu Leipzig 1893;1:14-49.
5. Tawara S. Das Reizleitungssystem des Saugetierherzens. Eine anatomisch-histologische Studie uber das Atrioventrikularbundel und die Purkinjeschen Faden. Jena: Gustav Fischer; 1906.
6. Koch W. Weiter Mitteilungen uber den Sinusknoten des Herzens. Verh Dtsch Ges Pathol 1909;13:85-92.
7. Thorel C. Uber den Aufbau des Sinusknotens und seine Verbindung mit der Cava superior und den Wenckenbachschen Bundel. Munch Med Woch 1910;57:183-90.
8. Aschoff L. Referat uber die Herzstorungen in ihren Bezeihungen zu den spezifischen Muskelsystem des Herzens. Verh Dtsch Ges Pathol 1910;14:3-35.
9. Monckeberg JG. Beitrage zur normalen und pathologischen Anatomie des Herzens. Verh Dtsch Ges Pathol 1910;14:64-71.
10. Sanchez-Quintana D, Davies DW, Ho SY, Oslizlok P, Anderson RH. Architecture of the atrial musculature in and around the triangle of Koch: its potential relevance to atrioventricular nodal reentry. J Cardiovasc Electrophysiol 1997;8:1396-407.
11. Hocini M, Loh P, Ho SY, Sanchez-Quintana D, Thibault B, de Bakker JM et al. Anisotropic conduction in the triangle of Koch of mammalian hearts: electrophysiologic and anatomic correlations. J Am Coll Cardiol 1998;31:629-36.
12. Racker DK. Atrioventricular node and input pathways: a correlated gross anatomical and histological study of the canine atrioventricular junctional region. Anat Rec 1989;224:336-54.
13. Racker DK, Kadish AH. Proximal atrioventricular bundle, atrioventricular node, and distal atrioventricular bundle are distinct anatomic structures with unique histological characteristics and innervation. Circulation 2000;101:1049-59.
14. Waki K, Kim JS, Becker AE. Morphology of the human atrioventricular node is age-dependent: a feature of potential clinical significance. J Cardiovasc Electrophysiol 2000;11:1144-51.
15. Zhang Y, Bharati S, Mowrey KA, Zhuang S, Tchou PJ, Mazgalev TN. His electrogram alternans reveal dual-wavefront inputs into and longitudinal dissociation within the bundle of his. Circulation 2001;104:832-8.
16. Paes de Carvalho A, de Almeida DF. Spread of activity through the atrioventricular node. Circ Res 1960;8:801-9.
17. Meijler FL, Janse MJ. Morphology and electrophysiology of the mammalian atrioventricular node. Physiol Rev 1988;68:608-47.
18. Bharati S, Lev M. Anatomy of the normal conduction system, disease-related changes, and their relationship to arrhythmogenesis. In: Podrid PJ, Kowey P, editors. Cardiac arrhythmias: mechanisms, diagnosis, and management. Baltimore, MD: Williams & Wilkins; 1995. p.1-15.
19. Anderson RH, Ho SY. The architecture of the sinus node, the atrioventricular conduction axis, and the internodal atrial myocardium. J Cardiovasc Electrophysiol 1998;9:1233-48.
20. Zeng W, Mazgalev T, Munk AA, Shrier A, Jalife J. Dual atrioventricular nodal pathways revisited: on the cellular mechanism of discontinuous atrioventricular nodal recovery and the gap phenomenon. In: Zipes DP, Jalife J, editors. Cardiac electrophysiology: from cell to bedside. Philadelphia: WB Saunders Co; 1995.p.314-25.
21. Moe GK, Preston JB, Burlington H. Physiologic evidence for a dual A-V transmission system. Circ Res 1956;4:357-75.
22. Mendez C, Moe GK. Demonstration of a dual A-V nodal conduction system in the isolated rabbit heart. Circ Res 1966;19:378-93.
23. McGuire MA, Lau KC, Johnson DC, Richards DA, Uther JB, Ross DL. Patients with two types of atrioventricular junctional (AV nodal) tachycardia. Evidence that a common pathway tissue is not present above the reentrant circuit. Circulation 1991;83:1232-46.
24. Schuilenburg RM, Durrer D. Atrial echo beats in the human heart elicited by induced atrial premature beats. Circulation 1968;37:680-93.
25. Denes P, Wu D, Dhingra R, Amat-y-Leon F, Wyndham C, Rosen KM. Dual atrioventricular nodal pathways. A common electrophysiological response. Br Heart J 1975;37:1069-76.
26. Jackman WM, Beckman KJ, McClelland JH, Wang X. Friday KJ, Roman CA et al. Treatment of supraventricular tachycardia due to atrioventricular nodal reentry by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med 1992;327:313-8.
27. Haissaguerre M, Gaita F, Fischer B, Commenges D, Montserrat P, d'Ivernois C et al. Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 1992;85:2162-75.
28. Billette J, Janse MJ, van Capelle FJ, Anderson RH, Touboul P, Durrer D. Cycle-length-dependent properties of AV nodal activation in rabbit hearts. Am J Physiol 1976;231:1129-39.
29. Markowitz SM, Stein KM, Mittal S, Lerman BB. Dual atrionodal physiology in the human heart. In: Mazgalev TN, Tchou PJ, editors. Atrial-AV nodal electrophysiology: a view from the millennium. Armonk, New York: Futura Publishing Company; 2000.p.353-70.
30. Tai CT, Chen SA, Chiang CE, Lee SH, Wen ZC, Chiou CW et al. Complex electrophysiological characteristics in atrioventricular nodal reentrant tachycardia with continuous atrioventricular node function curves. Circulation 1997;95:2541-7.
31. Sheahan RG, Klein GJ, Yee R, Le Feuvre CA, Krahn AD. Atrioventricular node reentry with "smooth" AV node function curves: a different arrhythmia substrate? Circulation 1996;93:969-72.
32. Janse MJ. Influence of the direction of the atrial wave front on A-V nodal transmission in isolated hearts of rabbits. Circ Res 1969;25:439-49.
33. Spach MS, Lieberman M, Scott JG, Barr RC, Johnson EA, Kootsey JM. Excitation sequences of the atrial septum and the AV node in isolated hearts of the dog and rabbit. Circ Res 1971;29:156-72.
34. McGuire MA, de Bakker JM, Vermeulen JT, Opthof T, Becker AE, Janse MJ. Origin and significance of double potentials near the atrioventricular node. Correlation of extracellular potentials, intracellular potentials, and histology. Circulation 1994;89:2351-60.
35. Rosembaum DS, Jalife J. Optical mapping of cardiac excitation and arrhythmias. Armonk, New York: Futura Publishing Company; 2001.
36. Mazgalev TN, Efimov IR. Optical mapping of impulse propagation in the atrioventricular node. In: Rosenbaum DS, Jalife J, editors. Optical mapping of cardiac excitation and arrhythmias. Armonk, New Yourk: Futura Publishing Company; 2001.p.157-76.
37. Wu J, Wu J, Olgin J, Miller JM, Zipes DP. Mechanisms underlying the reentrant circuit of atrioventricular nodal reentrant tachycardia in isolated canine atrioventricular nodal preparation using optical mapping. Circ Res 2001;88:1189-95.
38. Maury P, Raczka F, Piot C, Davy JM. QRS and cycle length alternans during paroxysmal supraventricular tachycardia: what is the mechanism? J Cardiovasc Electrophysiol 2002;13:92-3.
39. Skanes AC, Krahn AD, Yee R, Klein GJ. AV nodal modification for ventricular rate control of atrial fibrillation. In: Mazgalev TN, Tchou PJ, editors. Atrial-AV nodal electrophysiology: a view from the millennium. Armonk, New York: Futura Publishing Company; 2000.p.447-65.
40. Zhang Y, Mowrey KA, Bharati S, Mazgalev TN. A novel index reveals dual pathway conduction during atrial fibrillation [abstract]. J Am Coll Cardiol 2002;39:123A.