메뉴 건너뛰기




Volumn 17, Issue 2, 2003, Pages 86-91

Effects of benzo[a]pyrene on tissue activities of metabolizing enzymes and antioxidant system in normal and protein-malnourished rats

Author keywords

Antioxidants; Benzo a pyrene; Metabolising enzymes; Protein malnutrition; Rat

Indexed keywords

ANTIOXIDANT; BENZO[A]PYRENE; CARCINOGEN; CYTOCHROME P450 1A1; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDE; LIVER ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SUPEROXIDE DISMUTASE;

EID: 0037648978     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.10064     Document Type: Article
Times cited : (9)

References (39)
  • 2
    • 0028380120 scopus 로고
    • Influence of combined deficiency of fat and vitamin A on benzo(a)pyrene-induced lung carcinogenesis in rats
    • Khanduja KL, Koul IB, Sehgal S. Influence of combined deficiency of fat and vitamin A on benzo(a)pyrene-induced lung carcinogenesis in rats. Indian J Exp Biol 1994;32(2):124-127.
    • (1994) Indian J. Exp. Biol. , vol.32 , Issue.2 , pp. 124-127
    • Khanduja, K.L.1    Koul, I.B.2    Sehgal, S.3
  • 3
    • 0029948537 scopus 로고    scopus 로고
    • Effect of dietary restriction on benzo[a]pyrene metabolic activation and pulmonary BaP-DNA adduct formation in mouse
    • Chen W, Zhou Y, Nichols J, Chung KT, Hart RW, Chou MW. Effect of dietary restriction on benzo[a]pyrene metabolic activation and pulmonary BaP-DNA adduct formation in mouse. Drug Chem Toxicol 1996;19(1/2):21-39.
    • (1996) Drug Chem. Toxicol. , vol.19 , Issue.1-2 , pp. 21-39
    • Chen, W.1    Zhou, Y.2    Nichols, J.3    Chung, K.T.4    Hart, R.W.5    Chou, M.W.6
  • 4
    • 0025784027 scopus 로고
    • Cytochrome P450 multiplicity of isoforms, substrates, catalytic and regulatory mechanisms
    • Porter TD, Coon MJ. Cytochrome P450 multiplicity of isoforms, substrates, catalytic and regulatory mechanisms. J Biol Chem 1991;266:13469-13472.
    • (1991) J. Biol. Chem. , vol.266 , pp. 13469-13472
    • Porter, T.D.1    Coon, M.J.2
  • 5
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450s
    • Gonzalez FJ. The molecular biology of cytochrome P450s. Pharmacol Rev 1988;40:243-288.
    • (1988) Pharmacol. Rev. , vol.40 , pp. 243-288
    • Gonzalez, F.J.1
  • 6
    • 0025895757 scopus 로고
    • Reactions and significance of cytochrome P450 enzymes
    • Guengerich FP. Reactions and significance of cytochrome P450 enzymes. J Biol Chem 1991;260:10019-10022.
    • (1991) J. Biol. Chem. , vol.260 , pp. 10019-10022
    • Guengerich, F.P.1
  • 7
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzalez FJ, Gelboin HV. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Met Rev 1994;26(1/2):165-183.
    • (1994) Drug Met. Rev. , vol.26 , Issue.1-2 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 8
    • 0019142866 scopus 로고
    • Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity
    • Benson AM, Hunkeler MJ, Talalay P. Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 1980;77(9):5216-5220.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , Issue.9 , pp. 5216-5220
    • Benson, A.M.1    Hunkeler, M.J.2    Talalay, P.3
  • 9
    • 0035209568 scopus 로고    scopus 로고
    • The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism
    • Fisher MB, Paine MF, Strelovitz TJ, Wrighton SA. The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism. Drug Metab Rev 2001;33(3/4):273-297.
    • (2001) Drug Metab. Rev. , vol.33 , Issue.3-4 , pp. 273-297
    • Fisher, M.B.1    Paine, M.F.2    Strelovitz, T.J.3    Wrighton, S.A.4
  • 10
    • 0030598391 scopus 로고    scopus 로고
    • Effect of bitter melon (Momordica charantia) fruit juice on the hepatic cytochrome P450-dependent monooxygenases and glutathione S-transferases in streptozotocin-induced diabetic rats
    • Raza H, Ahmed I, Lakhani MS, Sharma AK, Pallot D, Montague W. Effect of bitter melon (Momordica charantia) fruit juice on the hepatic cytochrome P450-dependent monooxygenases and glutathione S-transferases in streptozotocin-induced diabetic rats. Biochem Pharmacol 1996;52:1639-1642.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1639-1642
    • Raza, H.1    Ahmed, I.2    Lakhani, M.S.3    Sharma, A.K.4    Pallot, D.5    Montague, W.6
  • 12
    • 0027517749 scopus 로고
    • Effects of riboflavin deficiency and riboflavin administration on carcinogen-DNA binding
    • Pangrekar J, Krishnaswamy K, Jagdeesan. Effects of riboflavin deficiency and riboflavin administration on carcinogen-DNA binding. Food Chem Toxicol 1993;31(10):745-750.
    • (1993) Food Chem. Toxicol. , vol.31 , Issue.10 , pp. 745-750
    • Pangrekar, J.1    Krishnaswamy, K.2    Jagdeesan, A.3
  • 13
    • 0016722995 scopus 로고
    • Experimental protein and energy deficiencies in rat
    • Anthony LE, Edozine JC. Experimental protein and energy deficiencies in rat. J Nutr 1975;105:631-648.
    • (1975) J. Nutr. , vol.105 , pp. 631-648
    • Anthony, L.E.1    Edozine, J.C.2
  • 14
    • 0020324474 scopus 로고
    • Developmental alteration of hepatic UDP-glucuronosyltransferase and sulphotransferase towards aldosterone and 4-nitrophenol in Wistar rats
    • Matsui M, Watanabe HK. Developmental alteration of hepatic UDP-glucuronosyltransferase and sulphotransferase towards aldosterone and 4-nitrophenol in Wistar rats. Biochem J 1982;204:441-447.
    • (1982) Biochem. J. , vol.204 , pp. 441-447
    • Matsui, M.1    Watanabe, H.K.2
  • 16
    • 0016333916 scopus 로고
    • Ethoxyresorufin: Direct fluorimetric assay of a microsomal O-dealkylation, which is preferentially inducible by 3-methylcholanthrene
    • Burke MD, Mayer RT. Ethoxyresorufin: Direct fluorimetric assay of a microsomal O-dealkylation, which is preferentially inducible by 3-methylcholanthrene. Drug Metab Dispos 1974;2(6):583-588.
    • (1974) Drug Metab. Dispos. , vol.2 , Issue.6 , pp. 583-588
    • Burke, M.D.1    Mayer, R.T.2
  • 18
    • 0016275313 scopus 로고
    • Glutathione S-transferase, the first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferase, the first enzymatic step in mercapturic acid formation. J Biol Chem 1974;249:7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 19
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E, Durom O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1963;61:882-888.
    • (1963) J. Lab. Clin. Med. , vol.61 , pp. 882-888
    • Beutler, E.1    Durom, O.2    Kelly, B.M.3
  • 20
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 21
    • 0021288839 scopus 로고
    • Spectrophotometric detection of lipid conjugated dienes
    • Recknagel RO, Glende Jr EA. Spectrophotometric detection of lipid conjugated dienes. Methods Enzymol 1984;105:331-337.
    • (1984) Methods Enzymol. , vol.105 , pp. 331-337
    • Recknagel, R.O.1    Glende E.A., Jr.2
  • 22
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autooxidation of pyrogallol and convenient assay for superoxide dismutase
    • Marklund SL, Marklund G. Involvement of the superoxide anion radical in the autooxidation of pyrogallol and convenient assay for superoxide dismutase. Eur J Biopchem 1974;47:469-474.
    • (1974) Eur. J. Biopchem. , vol.47 , pp. 469-474
    • Marklund, S.L.1    Marklund, G.2
  • 23
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 1999;91:1194-1210.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 24
    • 0017618911 scopus 로고
    • Drug metabolism under pathological and abnormal physiological states in animals and man
    • Kato R. Drug metabolism under pathological and abnormal physiological states in animals and man. Xenobiotica 1977;7(1/2):25-92.
    • (1977) Xenobiotica , vol.7 , Issue.1-2 , pp. 25-92
    • Kato, R.1
  • 25
    • 0023470769 scopus 로고
    • Effect of protein-calorie malnutrition on drug metabolising enzymes in rat liver
    • Narang AP. Effect of protein-calorie malnutrition on drug metabolising enzymes in rat liver. Indian J Physiol Pharmacol 1987;31(3):170-177.
    • (1987) Indian J. Physiol. Pharmacol. , vol.31 , Issue.3 , pp. 170-177
    • Narang, A.P.1
  • 27
    • 0030054707 scopus 로고    scopus 로고
    • Effect of dietary protein restriction on liver transcription factors
    • Marten NW, Sladek FM, Straus DS. Effect of dietary protein restriction on liver transcription factors. Biochem J 1996;317(Part 2):361-370.
    • (1996) Biochem. J. , vol.317 , Issue.PART 2 , pp. 361-370
    • Marten, N.W.1    Sladek, F.M.2    Straus, D.S.3
  • 28
    • 0029978949 scopus 로고    scopus 로고
    • Influence of diet and nutritional status on drug metabolism
    • Walter-Sack I, Klotz U. Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet 1996;31(1):47-64.
    • (1996) Clin. Pharmacokinet. , vol.31 , Issue.1 , pp. 47-64
    • Walter-Sack, I.1    Klotz, U.2
  • 29
    • 0028967274 scopus 로고
    • Effect of long term iron deficiency on the activities of hepatic and extrahepatic drug metabolising enzymes in Fischer rats
    • Rao NJ, Jagadeesan V. Effect of long term iron deficiency on the activities of hepatic and extrahepatic drug metabolising enzymes in Fischer rats. Comp Biochem Physiol B Biochem Mol Biol 1995;110(1):167-173.
    • (1995) Comp. Biochem. Physiol. B. Biochem. Mol. Biol. , vol.110 , Issue.1 , pp. 167-173
    • Rao, N.J.1    Jagadeesan, V.2
  • 30
    • 0024724961 scopus 로고
    • Study of activating and conjugating enzymes of drug metabolism in zinc deficiency
    • Jagadeesan V. Study of activating and conjugating enzymes of drug metabolism in zinc deficiency. Indian J Exp Biol 1989;27(9):799-801.
    • (1989) Indian J. Exp. Biol. , vol.27 , Issue.9 , pp. 799-801
    • Jagadeesan, V.1
  • 32
    • 0031586757 scopus 로고    scopus 로고
    • Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene
    • Kim KB, Lee BM. Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene. Cancer Lett 1997;113(1/2):205-212.
    • (1997) Cancer Lett. , vol.113 , Issue.1-2 , pp. 205-212
    • Kim, K.B.1    Lee, B.M.2
  • 33
    • 0028324459 scopus 로고
    • Cytochrome P450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: Opportunities and limitations
    • Yang CS, Smith TJ, Hong JY. Cytochrome P450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: Opportunities and limitations. Cancer Res 1994;54:1982-1986.
    • (1994) Cancer Res. , vol.54 , pp. 1982-1986
    • Yang, C.S.1    Smith, T.J.2    Hong, J.Y.3
  • 34
    • 0035018226 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo
    • Thapliyal R, Maru GB. Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol 2001;39:541-547.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 541-547
    • Thapliyal, R.1    Maru, G.B.2
  • 35
    • 0028040226 scopus 로고
    • Drug metabolising enzymes in ligand-modulated transcription
    • Nebert DW. Drug metabolising enzymes in ligand-modulated transcription. Biochem Pharmacol 1994;47(1): 25-37.
    • (1994) Biochem. Pharmacol. , vol.47 , Issue.1 , pp. 25-37
    • Nebert, D.W.1
  • 36
    • 0036204296 scopus 로고    scopus 로고
    • Glucuronidation: An important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues
    • Zheng Z, Fang JL, Lazarus P. Glucuronidation: An important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. Drug Metab Dispos 2002;30(4):397-403.
    • (2002) Drug Metab. Dispos. , vol.30 , Issue.4 , pp. 397-403
    • Zheng, Z.1    Fang, J.L.2    Lazarus, P.3
  • 37
    • 0035913673 scopus 로고    scopus 로고
    • Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk
    • Zheng Z, Park JY, Guillemette C, Schantz SP, Lazarus P. Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk. J Natl Cancer Inst 2001;93:39-46.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 39-46
    • Zheng, Z.1    Park, J.Y.2    Guillemette, C.3    Schantz, S.P.4    Lazarus, P.5
  • 38
    • 0025871840 scopus 로고
    • Roles of UDP-glucuronosyltransferases in chemical carcinogenesis
    • Bock KW. Roles of UDP-glucuronosyltransferases in chemical carcinogenesis. Crit Rev Biochem Mol Biol 1991;26:129-150.
    • (1991) Crit. Rev. Biochem. Mol. Biol. , vol.26 , pp. 129-150
    • Bock, K.W.1
  • 39
    • 0033835229 scopus 로고    scopus 로고
    • Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase, and microsomal epoxide hydrolase by 1,7-phenanthroline: Comparison with oltipraz, tert-butyl-4-hydroxyanisole and tert-butylhydroquinone
    • Lamb JG, Franklin MR. Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase, and microsomal epoxide hydrolase by 1,7-phenanthroline: Comparison with oltipraz, tert-butyl-4-hydroxyanisole and tert-butylhydroquinone. Drug Metab Dispos 2000;28(9):1018-1023.
    • (2000) Drug Metab. Dispos. , vol.28 , Issue.9 , pp. 1018-1023
    • Lamb, J.G.1    Franklin, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.